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Check Thyroid and Adrenal hormones. Your HPTA is likely messed up.

Could be from Test lowering Cortisol via a reduction in ACTH. This happened to me.

Opioids totally crashed my Adrenals. This is a known consequence that doesn’t get enough attention in my opinion. Maybe get ACTH, Cortisol, DHEA checked if you haven’t already. TRT is tough on guys with weak adrenal function. Good luck.

It absolutely does make sense. Not sure what you are unable to understand.

Seems like a really low dose. If you are just starting with thyroid meds, then low and slow is the way to go. Good Luck AGD!

175 mcg of T4 has helped me lose some weight. T3 has the somewhat paradoxical effect of fat gain with me. Apparently this is not uncommon. T3 can increase hepatic gluconeogenesis and increase insulin. T3 can also drive aromatase and result in an increase in estrogen.