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Thinking about TRT and could use some guidance
The following article was cited: https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02039 Finasteride, a 5-alpha reductase (5α-R) inhibitor, is a widely used drug for treating androgen-dependent conditions. However, its use is associated with sexual, psychological, and physical complaints...- Seagal
- Post #26
- Forum: Testosterone Basics & Questions
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The holy Grail of nutritional research regarding red meat consumption and lack of evidence of harm.
What about dessert?- Seagal
- Post #3
- Forum: Nutrition and Supplements
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Wild ride! Went from 120mg > 100mg > 80mg > 90mg. T is higher at 90mg 3x a week than 100mg 2x a week
They should not misinform and mislead people.- Seagal
- Post #14
- Forum: Testosterone Side Effect Management
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Thinking about TRT and could use some guidance
Can you take about 4 weeks vacation or long-term cut your work hours in half? Can you take 2 months pause of fin? I guess your idea is that TRT gives that boost that would balance out your work stress. Maybe it would help (short term). Only opinions here, nobody can know for sure what's the...- Seagal
- Post #19
- Forum: Testosterone Basics & Questions
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Tight or knotted muscles from TRT?
Did you try magnesium supplements?- Seagal
- Post #2
- Forum: Testosterone Basics & Questions
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Wild ride! Went from 120mg > 100mg > 80mg > 90mg. T is higher at 90mg 3x a week than 100mg 2x a week
Yes. Your body will adjust. Maybe later you can tolerate more T and maybe it would give more benefits then.- Seagal
- Post #9
- Forum: Testosterone Side Effect Management
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Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis
Have recently added Q10 (mitochondria energy) and Rhodiola Rosea (dopamine).- Seagal
- Post #5
- Forum: Mental Health
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DHT Cream Plus Testosterone Propionate = Major Libido Boost
Did anybody try dopamine nootropics? They usually have a short halftime, thus supposedly no interference with sleep. Rhodiola rosea, modafinil?- Seagal
- Post #440
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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DHT Cream Plus Testosterone Propionate = Major Libido Boost
HGH makes me tired. Some use it before bedtime for better sleep.- Seagal
- Post #439
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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Boswellia the "best" supplement for pain management in knee osteoarthritis
Funny And probably no placebo effect with horses I took it 3 times per day. I think it reduced inflammation.- Seagal
- Post #4
- Forum: Pain Management Research
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Boswellia the "best" supplement for pain management in knee osteoarthritis
It helped me with knee pain.- Seagal
- Post #2
- Forum: Pain Management Research
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Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis
What supplements have helped you?- Seagal
- Post #2
- Forum: Mental Health
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Comparative efficacy and tolerability of nutraceuticals for depressive disorder: A systematic review and network meta-analysis
https://www.cambridge.org/core/journals/psychological-medicine/article/comparative-efficacy-and-tolerability-of-nutraceuticals-for-depressive-disorder-a-systematic-review-and-network-metaanalysis/5799A126D0B5677764562824C452D545 Abstract Background Nutraceuticals have been taken as an...- Seagal
- Thread
- depression nutraceuticals supplements
- Replies: 5
- Forum: Mental Health
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HCT and blood donation
Imo your hct was still good. I do not recommend you do blood donation to reduce your hct. Did you have any symptoms possibly related to hct?- Seagal
- Post #2
- Forum: Testosterone Side Effect Management
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Wild ride! Went from 120mg > 100mg > 80mg > 90mg. T is higher at 90mg 3x a week than 100mg 2x a week
IMO you have a very good absorption with SC injections. Imo your shbg looked better with 80mg. Could do 3x/w SC to achieve a higher trough level. That would get you closer to your magic number... You should include hct in your labs!- Seagal
- Post #4
- Forum: Testosterone Side Effect Management
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Inject hCG IM for better results?
https://pmc.ncbi.nlm.nih.gov/articles/PMC6676071/ Figure 1- Seagal
- Post #11
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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Inject hCG IM for better results?
So true. Had here discussions about androgel T level dropping to the end of the day. One member here kept on posting studies that show that levels are stable. Finally evidence accumulated and serum tests showed differently. It wasn't only me... That 10-20% 'outliers' often get 'averaged out' in...- Seagal
- Post #9
- Forum: When TRT Is Not Enough (ED, Libido, & More)
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TRT in Canada if borderline Testosterone and Prolactin?
Estrogen does increase prolactin and elevated estrogen can move balance towards less dopamine. @LookingForAnswers- Seagal
- Post #7
- Forum: Blood Test Discussion
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7.5mgs daily labs
Could be bit higher or bit lower. If you want to know for sure you would need to take blood several times the day to get an estimate of the daily variation. It might differ slightly from day to day. It really doesn't matter. I'm afraid the question was initially asked with malign intend stemming...- Seagal
- Post #19
- Forum: Blood Test Discussion
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7.5mgs daily labs
I noticed the timing too and thought about it. In my experience the SQ gives a delayed and flattened response. No idea when there would be a minor peak during the 24h window. Maybe we can agree that next time he measures before the injection. I really don't expect any relevant difference. Don't...- Seagal
- Post #15
- Forum: Blood Test Discussion
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7.5mgs daily labs
It's SQ and daily. Would be nice to have a 24h graph of T level in general but that's not the purpose here.- Seagal
- Post #13
- Forum: Blood Test Discussion
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TRT in Canada if borderline Testosterone and Prolactin?
You are right about your prolactin being only slightly above range. Also opinions vary about T optimization. Imo the information about your nutrition might be crucial. I recommend you try cyclic keto including 1-2 days per week where you eat 'normal' reloading on carbs. Did you get a test for...- Seagal
- Post #4
- Forum: Blood Test Discussion
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7.5mgs daily labs
Good starting dose and good starting level achieved, good absorption with SQ. You could wait few more weeks and let things settle, you might start feeling better on that dose/level. Imo an increase of about 10mg per week would be a good choice.- Seagal
- Post #2
- Forum: Blood Test Discussion
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Thyroid Labs for Dixiewrecked
No, never got the RT3 from my GP. I meant your mental symptoms. It felt like the benefits of the morning 6ug T3 phased out or I got used to it. Maybe I will try again. Partial cold shower in the morning after my normal shower has had positive effects. Eating a small breakfast instead of only...- Seagal
- Post #20
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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Updated Labs - Help Please
If that's the goal, I would need about 250mg TU per week. One SQ injection at glute region. No problem. Oral or topical requires even much more T and money. That's not the point here, right? I thought only the sudden lower E2 is the problem. Now that I understand your intention, it makes sense...- Seagal
- Post #31
- Forum: Blood Test Discussion
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Updated Labs - Help Please
Could just inject more SQ if it's not enough. I don't think that SQ is generally wrong or inferior.- Seagal
- Post #29
- Forum: Blood Test Discussion
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Updated Labs - Help Please
It's strange that your e2 is suddenly at the low end. IMO it's not necessary to inject ed when injecting SQ. I would go with eod SQ. What's going on with your wbcc and bilirubin?- Seagal
- Post #24
- Forum: Blood Test Discussion
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Thyroid Labs for Dixiewrecked
I felt like elevated e2 had these effects on me. I know, not the whole E2 discussion again. Just wanted to mention it to you. Adding a bit T3 in the morning helped for a while. I think the whole hype that TSH should be below 2.0 is nonsense.- Seagal
- Post #18
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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TRT in Canada if borderline Testosterone and Prolactin?
High prolactin can cause your symptoms! Your testosterone is not borderline. Do you take any medications?- Seagal
- Post #2
- Forum: Blood Test Discussion
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New to TRT. Received first labs. Concerned and need help.
Most interesting starting around 19 min Starting dose depends on baseline T level, age, health, shbg. Just another voice. Hope that distracts you both from your neverending debate ;) @Phil Goodman @Cataceous- Seagal
- Post #57
- Forum: Blood Test Discussion
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Pregnenolone pathways and outcomes
IIRC oral converts through digestive pathway (much more) to preg sulfate which transports preg to the brain and servers as storage molecule. The dose matters, too much oral preg makes me tired. Which aspects of your life are improved by topical pregnenolone? What doses did you try (oral...- Seagal
- Post #2
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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