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Defy Medical TRT clinic doctor
  1. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    Did you change your nutrition or meal portions? Do you supplement with carnitine?
  2. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    I'm sort of a highly sensitive person. So, if someone is in the same boat, better start with 0.5mg.
  3. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    1mg at once. Second day constipation.
  4. Seagal

    GHK-cu and DHT

    I have underlying MDD and maybe that's why GHK-cu has that effect for me. Impact on neurotransmitter regulation and anti-inflammatory effect in the brain are possible explanations.
  5. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    Your thread motivated me to look again for a source. Hope I got real Reta. I have started yesterday with 1mg.
  6. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    Retatrutide has a halflife of 5 days. Do you notice it? Would twice weekly be better?
  7. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    I have been testing 20mg TrenE per week, while reducing T dose. Impacted sleep negatively but feeling overall more awake. Going to test 10mg per week while having reduced TU from 125mg to 75mg. In think it would be best to have tren cream for circadian rhythm. Is this possible similar to t cream?
  8. Seagal

    GHK-cu and DHT

    Did you notice any mental effects from GHK-cu? I started yesterday (2mg) and it gives me a mental boost, like a long lasting double espresso. Maybe this is an initial effect? Histamine release?
  9. Seagal

    My Father is 70 years old and we just got his labs done. I'd like your advice

    That's the T reference for <39 yrs. How is the blood pressure. Would fix low sodium levels. Check B12 and folate. Metformin is a high dose and maybe too high. Is it once per day or split?
  10. Seagal

    Gaining weight on calorie deficit

    Maybe the maintain weight estimate is wrong ;) Burning fat, gaining muscles, holding more water?
  11. Seagal

    Retatrutide - A Game Changer in Obesity Pharmacotherapy

    Here it's more like 13E/mg. Anyone knows a reliable supplier within the EU?
  12. Seagal

    Peptide suppliers

    What about peptide suppliers in the EU?
  13. Seagal

    Test cyp 6 months - still can't dial in

    Maybe best to stop the trt experiment. Imho the bit more T YOU get from trt is unlikely to make a significant difference in muscle gain. Brain fog can have many causes...
  14. Seagal

    Variable-resistance training

    Do you take your own equipment (chains, bands) to the gym or is it already available? I haven't seen anyone in my gym using it with machines or free weights.
  15. Seagal

    Variable-resistance training

    Has anyone experience with variable-resistance training?
  16. Seagal

    Test cyp 6 months - still can't dial in

    Before TRT no ED and normal libido? Brain fog gone with Estradiol and Prolactin now at higher end? With your high FT you could further reduce the dose, and split your dose to 3x/week.
  17. Seagal

    Feminism and male testosterone

    Something is happening to men, and no one is talking about it. Child attachment and parenting expert Erica Komisar reveals how modern society is rapidly stripping men of their traditional roles, leaving many feeling lost, directionless, and disconnected from both their families and their...
  18. Seagal

    Second Opinion on Restarting TRT (Primary Hypogandism)

    You mentioned E2. Where was/is E2 on/off TRT?
  19. Seagal

    TRT vs Clomiphene: Effect on IGF-1

    What Nelson posted: " Magnitude matters clinically Even the largest falls with SERMs kept IGF-1 within the adult reference range in most subjects, so frank GH-deficiency symptoms were not seen. Testosterone-related rises were modest; reaching the upper-normal IGF-1 range is uncommon at...
  20. Seagal

    Estradiol 230 pmol/L too high?

    Wonder what her plan is. TT of 40? You could ask her! Your FT is already very high. Imo you should rather reduce and split the dose.
  21. Seagal

    Please tell me how vitamin D supplementation has caused calcium deficiency, let's discuss.

    AI: 1. The "Muscle Meat Only" Carnivore: This is the biggest risk. Someone who eats only steak and ground beef with no sources of dietary calcium (no bones, no dairy) is at high risk for a negative calcium balance. The body will maintain blood calcium by increasing PTH, which will pull calcium...
  22. Seagal

    What's the u-shape for estrogen?

    We get three hormones with TRT and strangely their ratios are not the same with topical, oral, injection and with different esters or IM, SC.
  23. Seagal

    Please tell me how vitamin D supplementation has caused calcium deficiency, let's discuss.

    What my AI thinks The core of your problem almost certainly lies in the interplay between Vitamin D, Magnesium, and Parathyroid Hormone. · Most Likely Scenario (90% Confidence): You have an underlying magnesium deficiency. Supplementing Vitamin D exacerbates this deficiency, leading to impaired...
  24. Seagal

    Need honest advice: Do I really need TRT? Low-normal T, low libido for years, anxiety/OCD background, little muscle growth

    Regarding your concerns about fertility, you could search the forum for oral testosterone. I have no experience with it but that's what I would use (if I had access to it) to start or try TRT.
  25. Seagal

    Need honest advice: Do I really need TRT? Low-normal T, low libido for years, anxiety/OCD background, little muscle growth

    I asked my AI, it suggested you try TRT. Imo, it sounds multifactorial. It's difficult to give any advice. Do you have a problematic porn consumption?
  26. Seagal

    Lowering trt dose/ increasing frequency of injections question

    To me it makes no sense. Maybe some looking only at the trough level and chase a magic number.
  27. Seagal

    Lowering trt dose/ increasing frequency of injections question

    If you keep the weekly T dose constant and increase the injection frequency, it will flatten the curve, i.e. it will reduce the peak and increase the trough T levels.
  28. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    This was your usual trt dose plus 5mg tren daily?
  29. Seagal

    Reaching orgasm

    Your T dose is probably too high. Is it 250mg/mL?
  30. Seagal

    Dihexa for Cognitive Enhancement

    Me neither. SLU-PP-332 did work for me but it is too expensive (EU).
  31. Seagal

    Tren Improves Cardiometabolic Risk Factors and Myocardial Tolerance to Ischemia-Reperfusion in Male Rats With Testosterone-Deficient Metabolic S

    That's my experience (Proviron, Anavar) but I felt like I had to state that. Nandrolone was terrible for me, however, most guys encounter only benefits.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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