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  1. S

    TRT - whats normal

    You could try cabergoline to reduce prolactin, and immediately observe the impact on libido and motivation. I would switch to twice weekly injections or SC injection in order to lower the T peak. I don't think that reducing the dose by 25mg will make much difference.
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    IS THIS LOW FREE T

    Congratulations and thank you for the update. Interestingly your SHBG issue is resolved, it dropped about 50% from pre-trt baseline.
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    Ferritin vs hematocrit, blood donation

    Dr Rudy Eberwein explains how to Manage Iron Overload: Causes, Supplements, Treatment
  4. S

    Supra physiological FT

    Dr Keith Nichols explains Why You May Need Supraphysiological Testosterone Levels.
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    Strange change in lab #s looking for tips or advice

    We have seen this difference in T levels between IM and SC stomach before. If SC is more convenient for you, then I think you need to inject more T than IM. I believe your delt injections were IM. It would be interesting to know what your E2 Levels were.
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    Increase trt dose with age?

    How much did your hematocrit increase?
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    Association Between Sex Steroid Hormones and Hematocrit in a Nationally Representative Sample of Men

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774012/ We did not have a hypothesis about the association between estradiol and hematocrit because to our knowledge, there is no direct mechanistic link between estradiol and erythropoiesis. Yet, we found that men with higher concentrations of...
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    Swapping red meat for herring, sardines and anchovies could save 750,000 lives, study suggests

    It seems that nowadays the nutrition recommendations include environmental concerns/ideology, unfortunately that is often not transparent.
  9. S

    My Experience On Jatenzo (Oral TRT) Log

    Did you take the vit d on empty stomach or together with a meal?
  10. S

    Anyone remember the original Xenadrine?

    I have trouble with late night carbs craving. I recently tried semaglutide. This certainly suppressed the hunger feeling but I felt overall unwell on it. Maybe it works for you. Regarding the feeling of satisfaction/accomplishment: it maybe sound stupid but just making a little list of few...
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    Anyone remember the original Xenadrine?

    Is this about nutrition, fat burn, energy or getting high? I remember this yellow subs....good old times. I used it for a while; addictive stuff. This yellow subs were too much for me for enhancing workout performance. Later tried just ephedrine, aspirin coffee if I needed to work through a...
  12. S

    Overcoming Brain fog

    Anti-depressive/psychotica might cause it. If you need them you could try reducing the dose.
  13. S

    Oral Finasteride, Oral Mixodil and PSA

    Congrats to your hair progress. Amazing change seems possible. I don't know about Fina and PSA but what you are stating makes sense. In addition you could get once per year an ultrasound examination.
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    Better with high free T or total T or both?

    Did you do the IM injections also daily? I feel my SC injected oil for about week under the skin (until it's absorbed into circulation, I guess). Thus I think that there is about one week stretch in blood level response compared to IM and therefore it might take much longer to achieve...
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    Hi, new guy (40) on TRT from the Netherlands

    My advice is to look at the previous post of @madman and maybe try 150mg instead of 175mg. Hematocrit sometimes goes down again after a while. Checking your BP is a good idea. Drink enough water. Most here will probably say that your estradiol is normal wrt the TT. Are you injecting SC or IM?
  16. S

    Hi, new guy (40) on TRT from the Netherlands

    Your hematocrit is at 0.59, according to the attached lab report. That seems to be too high. How are you feeling?
  17. S

    Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)

    The blood sampling device is a game changer
  18. S

    Androgel Generic 1% - 8 Year Use - Latest Bloodwork

    You could try splitting up your daily dosage into morning and evening/night application, or an additional application at evening/night.
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    Got Test results after 3 months 1% T-Gel . . . very rattled!

    Can you explain the reason for the difference to the study data you referenced?
  20. S

    Got Test results after 3 months 1% T-Gel . . . very rattled!

    They are mostly uninterested in optimizing mental health because they don't have an objective measure on paper and no guidelines and because there is another 'specialist' aka psychiatrist to deal with it.
  21. S

    Androgel Generic 1% - 8 Year Use - Latest Bloodwork

    So much for the study average model of stable levels!
  22. S

    Androgel Generic 1% - 8 Year Use - Latest Bloodwork

    There is a study that showed stable T levels over 24h with a slight peak few hours after applying the gel. Given this assumption, one would measure T in the morning before gel application. Then there seems to be another study (I don't have access to the paper), which shows the fluctuation in T...
  23. S

    My TRT Odyssey: Lab Results and More

    Very interesting, especially since I started SC.... Did you have any side effects (inflammation, swelling) at the SC injection site and which body part did you inject SC?
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    Bioavailable testosterone is associated with symptoms of depression in adult men

    https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2712976 Previous research provided evidence that testosterone treatment is effective in reducing depressive symptoms in hypogonadal or middle-aged men up to age 60 years.This meta-analysis provides important new evidence that...
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    Effect of Exercise for Depression: Systematic Review of Randomised Controlled Trials

    Abstract Objective To identify the optimal dose and modality of exercise for treating major depressive disorder, compared with psychotherapy, antidepressants, and control conditions. Design Systematic review and network meta-analysis. Methods Screening, data extraction, coding, and risk of...
  26. S

    Anemic with very low BP's since starting trt gel

    What was your T, hematocrit etc before starting T gel, and what is it currently?
  27. S

    First post. Can’t get E2 under control, starting to worry

    @BigTex how did you front-load TU? I used weekly 125mg as an example for the plots. I don't know what oil is used in my TU.
  28. S

    First post. Can’t get E2 under control, starting to worry

    Have you guys seen this research: Controlling the polycythemia effect associated with TRT I think madman's post of this research hasn't gotten much attention. Thanks for all the discussions and sharing of experiences. I gave up on optimizing my androgel with ancillaries (hcg, anastrozol, dhea...
  29. S

    Testosterone and prosocial behavior

    The trenbolone example was of course a teaser. I think by aggressive we rather mean assertive, competitive, something positive. There are different forms of aggressive behavior. When I am at the gym and I am more eager to move that weight, feel a much stronger impulse to push harder. Isn't...
  30. S

    Testosterone and prosocial behavior

    I haven't seen a placebo controlled study with 1g trenbolone per week. My point is, we should be careful with extrapolating from testosterone to any AAS, from TRT to huge T dose. Of course the underlying character of the person is the dominant factor.
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