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  1. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    I see, you are right. And here I thought I had a fix to BA/BB causing issues in some. Do you have any thoughts?
  2. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    https://www.ncbi.nlm.nih.gov/books/NBK539783/#:~:text=Excess%20acetylcholine%20in%20the%20brain,giddiness%2C%20confusion%2C%20and%20drowsiness. This doesn’t mention depression but many other articles do
  3. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    That sounds like the quintessential high acetylcholine symptom, I get the exact same feeling on eggs if eaten too often. I think we’ve found an explanation as to why some can’t handle BB/BA. Now, it’s clear that E works well for you, I might try it. I am only 3 weeks into cream though so I’m...
  4. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    https://pubmed.ncbi.nlm.nih.gov/11440272/#:~:text=These%20results%20predict%20that%20T3,synaptosomal%20Mg2%2B%2DATPase%20activity. It could be implied an issue with injectables comes from a thyroid issue
  5. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    I have noticed certain high choline foods give me bouts of restlessness, I eat very clean personally. I’ve tried carnivore, keto, Mediterranean etc. the thing is healthy foods are packed with choline so it’s not wise to avoid them. Instead it’s ideal to find ways to digest choline better. Looks...
  6. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    I have not, haven’t had the chance until recently
  7. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    https://pubmed.ncbi.nlm.nih.gov/6090685/
  8. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    My next appointment is in July and I’ll bring up prop. I do all of those and have persistent sleep issues. I’m currently reading an article on how benzyl alcohol decreases acetylcholinesterase in rat models, I’ve noticed that injectable test of either cyp or prop makes me far more sensitive to...
  9. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    Every morning IM, I would try EOD if I can’t get cream to feel the same but I think it might simply be too much dht crashing e2. We shall see. Again I wish I could be prop’s biggest fan but it messes with sleep just the same as cyp did. The day someone makes prop without BA will be a 3 day feast
  10. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    I’m going to try to replicate the prop feel by splitting it on shoulders and scrotum. You’re definitely on to something with the DHT/E2 ratio. I’m not a heavy duty aromatizer (for better or for worse). E2 labs it is then. I really, really wish prop wouldn’t cause me insomnia because it felt the...
  11. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    I think I’m going to try what funk said to do with cream, I’m not a heavy duty aromatizer and I admittedly haven’t gotten e2 measured since starting cream. Even on high dose cyp- the supposedly most aromatizing ester- my estrogen never got above 35. If the eth doesn’t work for you, you might...
  12. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    Seems you’re right, prop has a melting point of 118-123 °C according to google. It does dissolve well in ethanol. I wonder why propionate feels the best for me mood and libido wise despite the insomnia it causes. I’m on cream which theoretically should match prop’s quick action. Cyp felt awful...
  13. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    Defy medical does work with a handful of other pharmacies, I can ask around if anyone has the list of pharmacies they work with. I’m on cream now which works better and less side effects but the libido on prop was absolutely insanity. Even with the higher dht I haven’t been able to replicate it...
  14. Pnw0031

    First post. Can’t get E2 under control, starting to worry

    Anyone know if Empower can do custom blends of propionate with a different preservative? I felt the absolute best mentally and libido wise on prop but the same insomnia and hyper stimulation as you Funk. I know I’m allergic to BB/BA like you
  15. Pnw0031

    Is it true that an elevated hematocrit level on TRT does not require blood donation?

    Funny you mention thyroid here... I switched to cream from cypionate and the thyroid issues I had are reducing among other side effect alleviation. Mine was also in cotton seed oil. Now on 20% cream from empower, three clicks a day. Doing better!
  16. Pnw0031

    Cypionate vs Propionate for daily injections

    Prop gave me a weird over stimulation feeling. Not quite anxiety but can’t relax. I’ve since learned I struggle with histamine intolerance so I’ve been working on fixing that.
  17. Pnw0031

    I got bacteria infection help pla

    Fluoroquinolones fucked up my life, using peptides to reverse what was damaged.
  18. Pnw0031

    The Case Against Antidepressants

    After trying straight Allopregnanolone I know I can NEVER take SSRIs. I had a HUGE inverse effect where I was ridiculously angry at nonissues and overreacted to pretty much everything. I had a very minor argument the morning before I received my Allo preg that essentially revolved around someone...
  19. Pnw0031

    The Case Against Antidepressants

    Gotcha, going to start at 50mg
  20. Pnw0031

    The Case Against Antidepressants

    Thank you for the help, I’ve ordered both the fat soluble and ttfd versions of b1. What dose are you taking of TTFD? I watched through some of the Elliot Overton videos, so I know to expect the paradoxical reaction for a week. I’m still not excited to experience it! Better to have a week long...
  21. Pnw0031

    The Case Against Antidepressants

    Other than thiamine, which I started today, what are ways to fix sympathetic dominance?
  22. Pnw0031

    Pregnenolone: oral v. Cream v. Hcg injections

    I’ve tried doses as low as 1.25mg, same sides
  23. Pnw0031

    Pregnenolone: oral v. Cream v. Hcg injections

    My end goal is to essentially feel “normal” for someone my age I’m only 21, I had the procedure when I was 18 and I’ve been struggling with consistent sleep, low libido and not feeling like I should. I have an excellent diet and workout every week day
  24. Pnw0031

    Pregnenolone: oral v. Cream v. Hcg injections

    Yes I’ve been on trt since 2019, I haven’t tried hcg though. Would you recommend looking into hcg alongside trt? My trt dose is 85mg weekly split into daily doses which gets me a FT of 140 pg/ml.
  25. Pnw0031

    Pregnenolone: oral v. Cream v. Hcg injections

    I want to love pregnenolone but it makes me feel just… weird. Like I’m tweaking almost, get super stiff and get oddly socially awkward also anxious. Anyone know why this is? I’m assuming it’s due to a choline reaction as I seem to be sensitive to other pro-cholinergic supplements. Estrogen was...
  26. Pnw0031

    Terrible anxiety and constantly at a heightened state on 100mg a week

    Out of curiosity how do you test for that gene mutation?
  27. Pnw0031

    Progesterone Dose for Men

    When I tried oral progesterone it creates crazy side effects for me. Felt bizarre and edgy like I was on some kind of drug.
  28. Pnw0031

    Terrible anxiety and constantly at a heightened state on 100mg a week

    What’s your shbg? I’ve noticed crashed shbg has given me that exact feeling. Currently in the process of repairing it
  29. Pnw0031

    Cypionate vs Propionate for daily injections

    I inject AM as well but I know some people try nighttime injections. I’m thinking of restarting pregnenolone but I’m looking for a cream form as I recall someone saying on here they did better with pregnenolone cream. Also starting raloxifene to fix puberty gyno and potentially raise my shbg...
  30. Pnw0031

    Cypionate vs Propionate for daily injections

    Sweet that’s my exact protocol, what time of day are you injecting and are you adding any supplements or other hormones along with the test prop?
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