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You sound like me to a T. Took me a good 10 years and over 15k€ worth of supplements to realize I felt better with nothing but food and Betaine HCL to digest it. Do you have any clue as to why we react in such an extreme way to all those apparently benign OTC vitamins, when others can just chug...

Good idea, will try Drinking 1.5L of water everyday for 3 years from copper pipes.

Thank you for taking the time to respond. I indeed feel way worse when taking B vitamins and Zinc, however I find myself in quite a conondrum as my hair analysis shows copper levels 10 times above the top of the range and zinc levels 1/10th of what I should have at the minimum. Copper overload...

I so wish you and every single person who liked your post were in my shoes for one hour only. You would beg your way out of this living hell that is post AI e2 receptor desensitization.

I'm getting so tired of this low e2 life. My e2 on paper is normal, but no one believes me when I say my receptors have been desensitized. All of this just because I took arimistane on its own for a month back in 2013, and then did 3 cycles of aromasin on its own in an attempt to boost my...

Too bad, I wish every story would happily end like this one : https://forum.propeciahelp.com/t/estrodiol-gel-success/7992

That's already a lot of symptoms. HCG never improved things, Clomid made things worse. Just ordered an estradiol cream, never tried exogenous e2 before. Blood test shows mid range e2.

Took aromasin in 2015 to try and boost my testosterone naturally. 12.5mg/day for 3 weeks. Made me go flat, depressed, no interest and no pleasure in anything. Still the same 9 years after. Gets slightly better when I'm on testosterone but nowhere close to how I was before on nothing.

What we want is not necessarily a constant stream of supplemental e2 floating around. We want to reactivate the estrogen receptors that have been shut down by flooding them with exogenous e2, and then let them live their life. Has anyone had success with this strategy ?

I am Goingstronger, and I gave up the transdermal propionate, it crystalized way too much to dissolve again. I'm back to test base in DMSO.

Can you post the link ?

Yep. Unfortunately phlojel's absorption rate is not very high and it takes ages to dry. Unlike DMSO where it's dry in 15 minutes and you don't risk contaminating anyone.

Gotta give this man props. The best I have ever felt is on test base + DMSO. Feels so different than esterified test. The hassle is you have to use it twice a day for consistent levels, but the second application is more for the ego of having high test all the time, you don't exactly "need" it.

Doesn't dissolve at all in either DMSO or pure ethanol. Recently made the experiment.

Because it's quite a hassle to apply DMSO twice a day rather than once.

Thank you ! I first got the idea of a transdermal with an ester thanks to my local compounding pharmacy. They make a testosterone propionate cream, and blood levels are far higher at the 24h mark than with test base cream of equal concentration (100mg/ml), meaning the ester does make it past...

Test base doesn't dissolve in olive oil even after heating for a long time. You need to add a solvent like tocopherols, ethanol, BA or DMSO.

I've tried 200 proof alcohol, it doesn't dissolve steroids as well as BA. In fact, pure ethanol dissolves test at 160mg/ml. BA dissolves test at 580mg/ml. Ethanol + DMSO doesn't do much more than DMSO alone.

Oh I know there is no issue at all from DMSO, I've been using it for years and love it. I was more concerned with the BA, being shuttled in the blood circulation thanks to the DMSO. BA has apparently high toxicity at very low dose. Indeed some formulations are gritty when you mix with DMSO...

Hey Big, I have been on a few transdermal formulations of my own for the past 5 years, and tend to stick to Test base + DMSO. However benzyl alcohol is invaluable in that it dissolves almost anything, which means I could do testo prop + DMSO + BA. Is your wife still on this formula ? Does she...