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I have similar experience with subq as well, I noticed that my T:E2 and DHT:E2 ratio gets skewed towards in favor of estrogen. I think it is because of local estrase activity. Estrase enzymes are available in other tissues of body not just blood, and it could be that since the depot of...

This might be true, from my experience the positive effects of proviron seems to be transient and consistent usage always result in diminishing returns.

Assuming high free DHT doesnt have negative feedback loop-like activity on the 5ar enzyme. Why would decreasing SHBG not result in higher free androgen levels in a steady state environment? Is it because of increased liver clearance of androgens?

Proviron is heavily dependent on underlying trt protocol. Since all of the androgenic effects of Proviron are mediated through liberating DHT bound to SHBG. On low dose protocols, there isnt enough DHT bound to SHBG begin with and hence non-significant androgenic boost/libido. I have used upto...

I am from Germany, and the product I use is called Tostran 2%. I find it has a little less alcohol content and it also dries out in a bit more time than usual. Proviron @ 25mg should feel like something.

May I ask the reason for adding TNE? And why do you think it is better (or different) than TE/TP blend?

Do you have labs on this protocol? What are you T levels (free, total), e2 or shbg?

Struggled with the entire time I have been on trt, which is atleast 3 years on and off. All of the standard doses of trt made me look much more uglier because of the moon face. This is the first time I am trying to be within or close to age matched T levels with a microdose protocol, and its...

Hi WillyT, Thanks for responding. I am glad that you are happy with the results you get from Test Propionate. I tried TP myself a while ago and didnt like the high E2 I got from it. Since TP peaks quite high so did my aromatization. I could feel the phase of day where T would dominate and...

I am not sure if I should comment on this really old thread. But I am trying something similar since all of the usual doses (100-125mg /wk) of trt is too much for me and has resulted in alot of facial bloat. I am trying to shoot for 600ng/dl range to see if reduce testosterone levels would help...

My levels have always been ~1.5 ng/ml and I think it is the reason that TRT has not improved my libido.

It is just a urinary catecholamine test, dont know anything much more than that at this point. Please let me know what your progesterone levels comes back to.

Source : https://www.albertahealthservices.ca/assets/wf/lab/wf-lab-bulletin-falsely-elevated-progesterone-results-due-to-cross-reactivity-with-dhea-s.pdf That is where I read about the cross reactivity of DHEAs and progesterone.

DHEA sulfate can skew the result towards the higher end in Progesterone assay.

Thanks for the feedback everyone, I will implement the changes in protocol advised by @Nelson Vergel and @Cataceous. On progesterone, is it fine or is it high enough to cause problems ?

For the first 3 months, I was on low dose trt and no hcg. Anxiety wasnt that bad, libido and erections were weaker than pre trt. Since then to test the high progesterone hypothesis I went on the higher try dose, 50mg eod. Libido improved and erections but not still better than pre trt. At this...

I feel even worse on low dose, I started with 30mg EOD, no libido, joint pain and acne.

Thanks for the reply. The progesterone test is from when I haven't started taking HCG, I started HCG to increase Estradiol such that the Prog to E2 could improve in favor of E2. The only source of my excess progesterone is adrenals because when the test was taken my HPTA was suppressed for more...

@StepbyStep I also have slightly high levels of DHEA SO4 (500 ug/dl) with Progesterone 1.5ng/ml, it is due to my adrenals being overactive. I also have a fast resting heart rate, and though I am fit and have been soccor for many years I could never develop adequate amounts of endurance and If I...

Hi All, this is my second post here and it is going to be a long one so please bear with me. I am amazed at the quality and depth of information available here, and grateful for the advice and help that experienced men on TRT provide here. Bloodwork : (After 3 months on TRT) Total...

First of all, thank you for such a detailed response. Do you think that If someone were to decrease their SHBG then only their Total Testosterone (TT) will decrease and Free Testosterone (FT) remain unchanged? If that is the case, then SHBG should not have any effect symptom resolution or is it...

Isnt it weird since the free Test is suppose to be ~2% of total Test ?

Shouldnt the unit for Free Testosterone be ng/dL ?

Hello all, I have seen this idea thrown around on trt and steroids forums that low SHBG causes high free E2 and that the use of DHT derivatives like Proviron, Anavar can cause gyno by lowering shbg = > high free Test => more aromatization. But as per this study SHBG preferentially binds to DHT...