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  1. M

    A cruel irony of TRT

    Learning that. Working with my psychiatrist, who's also a neurologist. My wife bailed on another assessment at a recommended memory clinic. Her niece and my doctor told me to gently persist in getting her to go. She said yes, though I don't believe her and rebooked the appointment, now...
  2. M

    For those who are struggling on TRT

    My urologist prescribes compounded cream. 10%. That doesn't work for me. I either needed multiple applications through the day or higher concentration. I believe Empower's is 50 mg per click. He'd probably prescribe it since I'm the problem patient. Mental sides, for me, would be seriously...
  3. M

    For those who are struggling on TRT

    Again, I'm trying 50 mg per week because, like @sh1973, I've tried every protocol/dosing, including pellets and compounded cream. Impressive looking labs are all I had. But when, out of frustration, I took several months off T, two years ago, I physically and mentally felt worse. My TT was...
  4. M

    For those who are struggling on TRT

    My urologist said, IIRC, the spread between the trough and peak is about 300. With injections, does DHT began to rise as soon as T is injected? Do they track each other? I understand there's an ezymatic process or processes involved. I ask because for a couple of months, I've been finding...
  5. M

    For those who are struggling on TRT

    I get what you're saying; that the day of the shot he gets a significant spike, then gradually down to the low point at day 7. Though there's criticism of once weekly injections, irrespective of the dose, you do have a slow roll down and after a couple of months, the trough is probably...
  6. M

    A cruel irony of TRT

    Thank you. Living through dementia with a family member or spouse is even worse than cancer, which took both my parents and I cared for them until they passed. My wife swears there's nothing wrong with her even as her memory is becoming fragmented and porous. She gets mad at me for my concern...
  7. M

    For those who are struggling on TRT

    No doubt. As @sh1973 said,it took about 10 to 12 weeks to fully feel the effects and that's what I've read,irrespective of dosage. Six weeks seems to be too short of a therapeutic window. I'm not going to presume anything, just do my weekly injection. My standard would be return of nocturnal...
  8. M

    For those who are struggling on TRT

    That's great! I know that numbers are just numbers. The real proof is always in how a man is feeling and functioning, irrespective of the dose and the labs. Several years ago did 30 mg, IM, daily. TT:1500 FT:500 DHT:75 E2: 60. In my head, super horny, but nothing going on below. And I...
  9. M

    For those who are struggling on TRT

    You know @highpull, the physician on T-Nation forum. He starts his patients, I believe, at 100, but most end up at between 150 and 200 mg per week. @highpull injects 200 mg, weekly. He's talks straight; no BS. He was asked about starting men on 50 mg per week and he said, 'No'. But he's...
  10. M

    For those who are struggling on TRT

    Maybe I missed it; free T on 52 mg, weekly? I'm sure not going to be critical. I'm one of those men whose tried every dosing protocol and have yet to find consistency. If it works and you feel/function good, that's all there is to say. Yet, IMO, men who do well on such a low dose are likely...
  11. M

    New here! 57 year old needing TRT

    I live in Florida and go to Publix, which is a major grocery chain. I turn in my rx and in one or two days, I have it. I also have the option of Optum Mail Order Pharmacy through my insurance. No price break but every six weeks they send me one or two vials, depending on what my doctor...
  12. M

    A cruel irony of TRT

    First time i tried Stendra, prescribed by my urologist I had a quick psychiatric reaction; made me hypomanic. I have bipolar. So I told my wife what was going on. She blew up. Ranted about how disgusting it was that men are taking those medicines to have sex. I countered that Viagra or...
  13. M

    A cruel irony of TRT

    Yes. Sorry about your father. He's as stubborn as my wife. She also totally trusts her primary who must have graduated last in medical school. But she's always been that way; places doctors on pedestals and accepts whatever they say.
  14. M

    A cruel irony of TRT

    Or a compounded cream applied in the vagina.
  15. M

    A cruel irony of TRT

    My urologist implants pellets in women.
  16. M

    A cruel irony of TRT

    Even when my wife and I were connecting,(me in my 40's, she in her 50's) it was once a week...maybe. We met when she was 47 and I was 42. Last year, my urologist graciously offered to order labs for her, though she wasn't a patient. Low estrogen, low progesterone, low testosterone. He wanted...
  17. M

    Glutathione Injections from Empower Pharmacy

    I'd have to find the study in my bookmarks, but it was found, as you say, that oral glutathione is quite bioavailable, contrary to what had been believed. IIRC, it took 3-6 months for the effects to be felt.
  18. M

    Glutathione Injections from Empower Pharmacy

    What about taking selenium? 100-200 mcg daily, or EOD. Or eating foods high in selenium such as fish and/organ meats.
  19. M

    PSA numbers increasing on testosterone- Should I stop TRT?

    After 6 months, and several PSA tests, my number, which had been slowly going down, is now 3.75, from its high of 4.95. Didn't add anything to the few supplements I take,nor change my diet all that much. Regardless, glad to see it declining.
  20. M

    Off TRT for over 3 months, interesting results

    I've heard his name but that's it. Have to look him up on YouTube. Thanks. You always have interesting things to say and share.
  21. M

    Off TRT for over 3 months, interesting results

    Switching to water soluble, dry vitamin D. About 14 or 15 years ago, I was taking 5000 IU, daily, without magnesium, and my blood level was 91. My primary freaked out and told me I had hypervitamitosis, though I didn't have any symptoms of it. I knew what to look for. So I took it a little...
  22. M

    Off TRT for over 3 months, interesting results

    O It's Quest and my free T was above range. I think their top is 228.
  23. M

    Off TRT for over 3 months, interesting results

    Just got my labs. TT: 889 FT: 240 E2(sensitive) 61. High hsCRP. I read, today, that stress, alone, can increase inflammation. Got a truck load between bipolar, poor sleep and my wife's worsening dementia. Diet is salmon, sardines and shrimp. Lots of Omega-3. And cold pressed extra virgin...
  24. M

    Off TRT for over 3 months, interesting results

    Review the thread only happy when estradiol is VERY low I'm revisiting this, as I avoided using an AI for years. Might very well have helped me. Now using anastrozole;.25 mg 3X weekly with 100 mg, Test E, IM, E5D. Over the years, tried anastrozole @ .25 weekly or twice a week. Nada. That's...
  25. M

    Supplemental estradiol?

    Thank you, Nelson. Problem for me is that using that stack or just L-Citrulline will make me hypomanic; irritable, agitated, as well as negatively impacting my sleep. If I eat a lot of watermelon, which I love, I end up with similar problems.
  26. M

    Supplemental estradiol?

    I know there are some men on here whose E2 crashed and they're trying to increase their estradiol with tablets. Nelson, I recall, was using estradiol tablets at one time. Dr. Neal Rouzier will prescribe if a patient's lipids are still elevated on T or no weight loss or erectile function. Their...
  27. M

    New here! 57 year old needing TRT

    Whether or not those sides are listed I don't know, but I experience them. Same problems with psych meds; I get side effects fairly soon after starting, without any benefits.
  28. M

    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    Ever try large weekly injections(200, 250 or 300 mg, either in one shot or split 2x weekly? Just a thought based on reading on another site. No expert, here, but, if the aromotase enzyme is functioning, though not efficiently, higher dosing of T, IMO, would kick it into gear. Perhaps...
  29. M

    An Unusual Source of Anxiety

    To add to my previous post about K2/Mk4 and anxiety, I've tried CoQ-10 as well, several times over the years, and for me, too, it increased my anxiety. 100 mg was too much for me.
  30. M

    Testosterone no ester in DMSO experiment

    How about Everclear or other 200 proof alcohol? Also, does test base dissolve well in olive oil? Thanks.
  31. M

    New here! 57 year old needing TRT

    Agree. On drugs.com user reviews, the men who post seem not to be on testosterone but go to their primary with the issue of ED and off the bat, are prescribed Cialis(tadalifil)or Viagra(sildenafil) or (Levitra)vardenafil. My urologist told me that a TT of 600 is needed for a good response to...
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