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It’s been almost a year since I started taking 400mg of pregnenolone a day in the morning on an empty stomach. I’ve tried different brands but settled on the Double Wood brand from Amazon for the price and effectiveness. Had a brief time where I tried stopping here and there and didn’t feel as...

Anyone had any luck in being on replacement doses of T3 / Liothyronine and not having their muscles go flat? 25-32mcg of T3 spread out throughout the morning completely fixes some debilitating gut issues I have, but makes my muscles go flat. My cortisol tends to run lower, so upping carbs too...

My doc usually uses Quest and I get my own tests through Quest and DiscountLabs, but my doc recently tried LabCorp because he said they gave him a better deal on a wider variety of tests. Half my results aren’t there and say things like ‘unable to calculate result since non-numeric result...

Finasteride is what originally lead me to all of this. Reading into things more lately, I read some people saying that the presence of 5AR metabolites like DHT up regulate 5AR in a positive feedback loop. Does anyone have any knowledge or experience with this?

Struggling to make sense of why my total testosterone is going down while my free testosterone and E2 are skyrocketing at the same dose and frequency (20-24mg daily, was also with 100iu HCG daily). My fasting glucose is usually 85. My A1C’s 5 and below. The rest of my blood work’s fine, lipid...

Got my latest blood test in. For whatever reason, at the same dose as my other blood tests (20mg testosterone and 100iu hcg daily subq), my total testosterone is actually dropping (1024 from 1200) and my free testosterone and presumably estrogen are rising (340 from 304 on free t). Doc forgot my...

Anyone been on Cialis for extended periods of time to comment on whether they became dependent on it? Granted if you had ED before taking it and it fixed it for you then I can see that being some form of dependence, but I’m mainly interested in people or anecdotes of others that have taken it...

I’ve been experimenting with a lower test dose (85mg a week alongside HCG vs 130-160mg a week alongside HCG). I felt better at first like everyone does when changing protocols, then chronic gut issues I’ve had seem to progressively be getting worse despite taking it easier on things that trigger...

I read someone in another thread mention that without enough iron, T3 can’t get into the cell. I’m familiar with the usual things you’d read on Thyroid and iron levels, and am wondering if anybody would know if it was involved in more than just helping convert T3 to T4 in an abstract way, and...

I’ve been dealing with some odd issues over the past years on HRT with periods of relative bliss in between. Among the issues, I have a marked inability to retain muscle glycogen despite any macro and electrolyte changes. Muscle and strength is still there and increased, and sometimes if I...

Been on HRT for a few years and still ironing out some lingering issues. Historically I can get my total T to 1300ish with a 200-215 free T and 50-57 E2 without an AI or anything with daily small injections of testosterone and HCG. My free T3 on labs is usually a little low (3.0-3.2), my rT3’s...