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Probably need rT3 and fT3 for a better picture. I was told by my doc that when we have dysfunctional thyroids, we can have episodic waves of good days/weeks and then, like bipolar disorder, be sunken for days/weeks. So this might be what's happening.

I started out with liothyronine (generic Cytomel) 5mcg/day. Doc said 7-10 days and reassess. I did 2-3 weeks at that dose and then went up to 10mcg, which is where I've been for the last month and half. I also changed testosterone esters, propionate instead of cypionate, and my quality of life...

Sounds like the same runaround I had with my primary. Luckily my hormone doc at Defy (Caleb Calkins) got everything figured out. T3 has been a lifesaver. I just started a new job and I have enough energy to withstand the day finally. I hope you get it figured out sooner than later.

So your thyroid is enlarged and they didn't want to do more blood tests? Odd. Was that free T4 or total? I started T3 meds and feel light-years better. The DHEA was definitely causing my fatigue and acne like sh mentioned above. Hopefully someone else can chime in and help. Hope you get it...

Thanks. Were your levels low as well? Hopefully this is helpful for others and I'm not hijacking the thread.

Will do. Would taking it for the last 4 days be enough for a reaction tho? Since it's a hormone and all.

What were your levels before taking it? Mine are mid-range but I also have some thyroid stuff going on. Doc recently said to start taking 25mg with my liothyronine (5mcg/day rn) and all I feel is extreme fatigue and some minor acne coming on.

How did you get off TRT? I meant to ask my doc at Defy today but forgot. Been wondering if there's a cut off point for how low testosterone has to be in order to rule it being a thyroid issue or hypogynodasim or possibly both.

My numbers are the same as the OPs. High rT3, mid-range T3, T4, mid (high) TSH. I have a family history of hypo in my family and I've been dealing with crazy lethargy after dialing in my TRT protocol (32mg EOD, 110mg/wk avg). First few weeks are fine then it feels like my body can't keep up...