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What do you think about this at-home test Kyzatrex is offering?

It would be interesting to see a study in older males on possible recovery of T and improvement in body composition with exercise, varying rates and types of physical training.

I didn't think it was possible to have exogenous T at any level without shutting down your own T, even incrementally. Supposedly the oral forms have less impact on shut down, but I haven't seen research on any specific values or proportionality. Sure would be holy grail for me. Maybe Madman...

Why would the TriMix not give a full erection? Also, did the BiMix erection last as long as that with TriMix?

Looking at your description, if that were me, I would first try some OTC products to stimulate testosterone, gain some weight through slightly more but better eating (red meat, high density nutrition foods) and lift fewer reps but heavier weight as opposed to endurance type exercise. I'd give...

Here's how I deal with my chronic LBP; 1. Posture: Always be aware of it when walking, sitting, lifting. Assume Z shape: Lay on back, feet on chair, 90 deg leg position. Neutral for spine. 2. I find an inside corner of kitchen counter and lift my self, elbows straight so feet off the...

What product and what dose would produce the physiological effects demonstrated in the study?

What is the status on availability of HCG now. Especially, California?

I'm thinking of giving Kyzatrex a try. Is it something one's own MD could prescribe? Of the two telemedicine providers listed on the Kyzatrex website, any opinion on best?

Interesting food for thought. Why would a man, or would not, consider just joining his partner in not having sex? How motivated would you be if you were not on TRT? Do you think you would feel the same at age 70, 80, 90? Is your marriage based on love or sex? What do your marriage vows mean...

Eberhard Nieschlag - Curriculum Vitae 1961-1967 Study of Medicine, University of Bonn and München 1967 Doctoral degree (Dr. med.), University of Bonn 1967-1968 Studies in Biochemistry at the University College London and training in Endocrinology at the MRC Unit in Edinburgh, Scotland 1968-1971...

This course, or similar should be made mandatory for physicians as part of required CE for license renewal. Male health matters-MHM!

I’m not sure what its mechanism of action is. It produces physiological effects of increased libido/sexual stimulation. Involuntary erections but different than Trimix. Side effects are annoying.

Good point. Similar to effects of PT-141.

If you have an erection, you have libido. But, one can have libido and not get an erection. That’s the real problem, IMO.

Betting it's activities related to poor posture or posture not supportive of spine health while performing those activities, including sitting.

I first found out about Bryan in 2016. Bought his book quite some time ago. Originally he cofounded SuperBeets company HumanN then moved on to compete with them. Other products with clinical efficacy to support the endothelium, which is what it's really all about. Such as Vascanox and...

Me at 25: Oh God, my eyes! <Limp> at 73: <woody> Time is relative: Einstein.

Sadly I've found, many older women don't care they have lost desire for sex. Stark contrast to older men.

I think topical cream of HGH + T + Lard is the secret.

Did you check for H63D gene variant? The main problematic ones for hemochromatosis are C282Y and H63D.

There is a lot to be said and way overdue about men's reproductive health. The disparity in awareness, attention to and spending on is egregious in my opinion. The difference in government supported expenditure is immense. Would reproductive rights not be an applicable argument for men? Men's...

As far as I know, the C282Y and H63D are the only problematic variants in terms of hemochromatosis and a conundrum in balancing with TRT. @FDV70 could shed more light on that probably.

Get genetic testing done by 23andme or another such service. It will reveal if you have a variant for the HFe gene, which could confound your expectations for TRT.

@Ribeye Have you taken both brand name Vylessi and generic (Compounding pharmacy) PT-141? What differences have you noticed, if you have?

This and the plastic mass in the oceans, worry me far more than the prospects of climate change.

Best relaxing initial sleep I get is with 5mg hydrocodone and 5mg Valium. Unfortunately, not something MDs feel comfortable prescribing. Some of the best sleep with the most refreshed feeling I've had has been following some surgeries. I almost look forward to them! Can't beat...

Interesting. Haven't heard of that use. Worth a try. Good show, Vince!

@50BMGdoesitforme Some other things to list if you want the comprehensive help package from here is age, weight, lifestyle and a whole bunch of lab test data. CBC, Complete iron panel, all thyroid stuff, lipid panel (Discounted Labs is great for this) and gene tests as mentioned. All stuff I...

B. No, that test won't tell you if you have hemochromatosis. You need to get genetic testing for HFe gene. There are two main variants. Highly recommend you don't do anything before you do this. Fred Vorck's protocol (Raising Ferritin Fast...) is insightful, but there are caveats to...

{"Transgender women, who were assigned male at birth but identify as female treated with estrogen have a 46 times higher risk of developing breast cancer compared to estrogen unexposed cis-men."} It would be interesting to see a risk profile compared to women overall.