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I m just checking with the community to see if there is a new discovery with Low SHBG individuals ? Any new treatment ? Any new strategies to raise it ? It is a bad curse .

I have searched for the answer endlessly and only got conflicting reports . Does Thyroid hormone ( T4,t3) reduce Estrogen or raise it ? What is their effects on the aromatase enzyme ? Thank you . All seems very confusing and I think the TRT/testosterone community could benefit from the correct...

I m in the process of restarting after TRT , but Clomid is a non-starter for me and Nolvadex also gave me libido issues . I want to choose Toremifene Citrate as the SERM post HCG but my doctor says it may not be available in pharmacies . Does anybody know if that is true ? Is there a pharmacy...

This study confirms that D-chiro-inositol raises Testosterone significantly and lowers E2 and Estrone : https://pubmed.ncbi.nlm.nih.gov/34078260/ Why is this not talked about anywhere ? Is there something wrong with the study ? Am I missing something ?

Is there a proven way or supplement for lowering IGF1 ? Besides the internet BS regarding diet .

For the guys who have labs on both . Does your SHBG tend to differ with injectable and Scrotal cream ? My SHBG goes from mid 20s to low teens on ANY dose or frequency of Test cyp . I was wondering if Cream is different ? Please let me know I am desperate.