Agreed.. Hopefully accurate calculators based on experimental data can be published.. Like the discussion initiated in the other board:
Calculate free testosterone with TruT by FPT
The older papers have too many simplistic assumptions. I quote the text from figure 2 of the paper you cited: Figure 2. Bland–Altman plots comparing cFT (right) and RIA (left) against EqD. Mean bias is 0 [95% CI 29.4 to 29.4] for RIA and -19.4% [95% CI 45 to 6.1] for cFT.
How do we reconcile...
This is the central problem. If the measurement (of total and free) is not precise then dosing becomes a trial and error. Either the person gets to supra-physiological or sub-therapeutic levels. Contributors to the substantial variation in on-treatment testosterone levels in men receiving...
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