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Did you ever bring your ferritin up? The sluggishness could just be due to that.

Hey hombre. I've had a similar experience, plus the studies all suggest it'll vary. Personally, I don't even test anymore. Just my opinion, but I think much of the testing on these sites is a waste of time. Testing because the dose is too high or there are symptoms from undiscovered issues...

What's your story and how do you feel? Are you supplementing dhea and were you awake long before the test? You should do more tests. As madman mentioned, your T is very low. Given the high homocysteine, might want to test b12 and folate. TMG and/or lots of eggs can get that down. 2,000...

I take undecanoate and think it's massively superior. I skimmed over what you wrote, and just comparing your experience to mine: - Far too frequent. Undecanoate half-life is 15-35 days depending. T should be dosed at 1/2-1 of the half-life. I get away w/ once every 2 weeks, which happens...

I've seen correcting thyroid raise total T ~100-200 or so, but that's usually from 200-400 up to 400-500. Never seen anything higher. May depend on your age and anything else (aas use, etc.).

looks okay if you want all t3. that's still hardly any t4. Body makes 100 mcg/day, and absorbs 60-80% of oral t4, so that's a little over 20 mcg t4 hitting your system, or 20%.

Interesting about the intolerance. Have you check your glucose metabolism? fasting glucose, a1c, fasting insulin, perhaps a glucose tolerance test (w/ 4 insulin pulls)

I asked the same question myself. What would the optimal Testosterone be? I don't know, but I did find the following interesting. The most interesting things I have found: 1. from a study I pulled, they had a regression equation, which suggests the average Total T level is 8x the Cyp...

I'd check your b12 with your MCV that high. A good b vitamin supplement might be helpful. And as mentioned above, you probably need thyroid hormone. I'd shop doctors until you find one that'll allow a trial. It could help your energy.

Sure thing! Hope everything works out for you. You might also want to look into lipoic acid and/or chromium too. Both otc and might help. Probably harmless anyways.

Low shbg is a marker of high insulin, and, your blood glucose is on towards the high end. You might want to test a1c and fasting insulin next time you do a round of tests, just to double check glucose metabolism.

to go back to your original question - yes, blood levels can fluctuate on the same dose and the same day by a surprising amount. Consider this: 600 ng/dl = .006 mg/l 5 liters of blood in the body = 600 ng/dl * 5 = .03 mg total in blood. It turns over really fast it seems. 100 mg...

that's from Defy?? That doesn't look that great to me. -you should do more thorough thyroid testing - adding in some t4 might be a useful intervention. - why the initial high dose of T with an ai? 100-120 mg/week w/ no ai works for most... - that's a high dose of fish oil. Make sure you...

Just fyi. I've had half a dozen friends feel better from adding in some t4 with their Total T4 in the 5-7 range. Boosting it up to 8-10 often gives them some more energy.

A few other obvious things stick out in your labs: - you may have an issue with blood sugar. I would test your fasting insulin and keep an eye on your a1c (average blood sugar over time) and fasting glucose. An oral glucose tolerance test (with insulin tested) is the gold standard if you can...

You probably can't lower your shbg. The body makes shbg to hold onto Testo longer since production is low.

definitely raise ferritin to 80-150. my wife has the same issue and it's taking her forever to get her iron up. She'll likely notice the difference. Vitamin d could be a bit higher too.

Those results don't seem too surprising to me. I'll try and find a study I found that dealt with this issue. It placed the individual variation in Total T as +/- 150 ng/dl measurements on the same day each week. I think it was 100 mg/weekly in 1 shot but in 3 weeks your results could be...

It's hard to say without knowing your protocol but unless that's the absolute peak of an infrequent dose protocol, then you should probably lower your dose. And ferritin is a body status marker for iron and you are severely iron deficient. You'll need iron supplements with a level that low...

I wouldn't say worthless. With a severe deficiency, they will likely be low but catching marginal status seems tougher. Zinc was said to rise after a meal with zinc or from supplements, and stay up for a while but would drop if there was no reserve. I've seen a nutritionist run 3 tests for...

serum zinc is readily available but zinc is under homeostatic control so serum can be normal without much of a reserve. Not sure about rbc zinc. You can test ceruloplasmin for copper too. It's to copper as ferritin is to iron, a storage form of sorts.

Sorry to come so late to the party. Hopefully your doctor mentioned you are Iron and Vitamin D deficient? They are both low enough to impact how you feel. Especially together. I shoot for 100-150 ferritin and 35-50 vitamin D. The iron could take a month to bring up - 100 mg elemental/day -...

thanks Vvs1. I might go with Defy. I'm an American living in London but I do make trips back to the US frequently. I could go to Dr. Hertoghe in Belgium. Hertoghe prefers gels (I think) and the American docs usually use enanthate. I would love to try 260 mg of Undecanoate every two weeks but...

Thanks for the insight guys. I am trying to double check to see if a group of people familiar with the issues think it's as big an issue as I do. Cheers

Hi. On the ndt you can expect a low total t4 and probably a low ft4. The t4/t3 ratio in ndt is much less than the ratio humans make. 38/9 vs 100/6 Some mix t4 with ndt to avoid the below range t4. Thyroid is generally pretty safe to supplement. It's obvious if your dose is too high.

Yes, I've seen studies like those. That's why I'm looking into it. I'm not just trying to bulk or have some porn star sex life. In fact, I specifically don't want those things. But if I do need it, I'll find someone who understands my argument.

and I do know that a low Total is a stronger diagnosis but I do think I probably do have low T signalling. Tinkering with an online free T calculator, my bio and f are equivalent to under 400 total if my shbg would be 25-40. In fact, once, we tried danzolol for a few weeks to lower shbg...

thanks for responding. @Vince. Yes, I could go back to the old doctor. There's also Defy medical and a few other shops. I did feel better before, although the this time around I would like a lower dose - 120 vs 180 /week. So I am a bit worried that what I remember as an improvement is from...

Hello everyone. I was on trt for a few years and came off to try and have kids. We have one on the way, so I'm weighing my options and thinking about going back on. Labs from a few months ago: Labcorp Total T 570 246 - 916 ng/dl Free T 7.3 8.7 -...