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    Things went sideways after lowering dose/adding AI

    So, after 8 weeks in, I was feeling great with maybe a little bit of water retention. Here are those labs. After reviewing with defy, we agreed to lower me from 160mg/week (two 80 week) to 140mg (two 70mg) and add 0.1mg adex per week. No HCG or anything else either course. Fast forward 3...
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    High E2 Symptoms?

    So as I posted in another thread, my E2 came back high (65) after my first 8 weeks at 160mg/week. Didn’t have much symptoms but defy and I agreed to lower me to 140mg/week and 0.1mg to 0.2mg Anastrozole weekly. I know it’ll take time for my dose change to reduce E2 symptoms but a few new things...
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    Moving to 3 days per week

    Per Defy’s suggestion as my E2 is up in the 60s 8 weeks into TRT and me not being fond of the idea of jumping to Anastrozole, they have suggested that I move from twice per week to three times per week to try and lower E2 (my SHBG also went from 67 to 37). Should I consider lowering my dose...
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    First round labs in

    So I’m 40, 8 weeks into TRT at 80mg twice per week. Feeling really good. Had about 2 weeks in. The middle where I felt like I reverted and then went back up to feeling like I did 10 years ago again. Went into this with TT 460 and SHBG at 67. No HCG, no AI. Prior to this, I was on Clomid...
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    TRT, HCG, and DHT

    Hi all I’m only 7 weeks into TRT with Defy. All good so far. First follow up in about 2 weeks with labs. Question for the group - I opted to keep things simple and start with just T Cyp @ 80mg twice per week (I have high SHBG). Again, things are going well and couldn’t care less about testicular...
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    Is subq less effective for some?

    Hi all, I’m 7 weeks into TRT with defy. I’m 40. Was in the mid 400’s TT since my mid 20s and finally felt too low so made the switch from Clomid monotherapy to TRT. Currently at 80mg twice a week. Been doing subq. Felt an immediate lift in mood, morning erections, muscle fullness, etc for the...
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