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  1. O

    My Ongoing TRT Mystery

    Saw them live a few times, awesome show!
  2. O

    My Ongoing TRT Mystery

    I saw that too, I believe it’s the CYP24a1. Sadly my dna test doesn’t have this one.
  3. O

    My Ongoing TRT Mystery

    Thanks man. I got his book and read it today, I also emailed him. I’ve never tried prog so this could be a big help. His descriptions also seem to fit my issues. Are you a fan of the band GBV?
  4. O

    My Ongoing TRT Mystery

    I’ll see if I can get Some lower dose d nearby and give it a shot. Thanks!
  5. O

    My Ongoing TRT Mystery

    Same with the b12s, good to know. I hope the citrate gives you a positive result. I agree that b12 and most all b vitamins feel like straight up crack to me and anger in a pill. The Sertraline and vit d low dose might be where I start. The benzos work but I am (surprise) scared to take...
  6. O

    My Ongoing TRT Mystery

    Do you only take the 600iu and nothing else with it? (K, magnesium, etc)?
  7. O

    My Ongoing TRT Mystery

    we have a lot in common then with the COMT thing. My b12 is 692 currently. I don’t think even cyano worked for me (sublingual). Have you tried hydroxy or andro b12? How is the citrate working? Mag has always been another total disaster for me, but I can’t figure out why.
  8. O

    My Ongoing TRT Mystery

    Not sure the d level, I was not taking magnesium. 10k was for sure too much. Magnesium (at least malate and glycinate caused panic and waking up freaking out). Have not tried citrate in years or even oxide. I do also have the GAD1 snps, but who knows if that stuff even has any medical...
  9. O

    My Ongoing TRT Mystery

    B’s make me rage. At least the complex does. Methyl ones also do a number one me. I get at this point it is almost comical that I seem to react to everything and I seem like a mental case and imagining all of this.
  10. O

    My Ongoing TRT Mystery

    Thanks man. Kidney stones were never an issue for me, and don’t run in my family. 10 years ago I was low in vit d (as always) and was taking 10000i.u. a day without k. Calcium shot up above 10.5 and I had two kidney stones. I haven’t touched it regularly since. Test injection was 75mg on...
  11. O

    My Ongoing TRT Mystery

    Thanks man. I used to take preg and feel great on it. My recent labs show it was around 63, so within range. I only took 5mg yesterday and today and it seems to have wrecked me.
  12. O

    My Ongoing TRT Mystery

    Years ago almost anything seemed to Work fine. I was caught up back then in chasing perfection. Now, everything seems to make me an emotional wreck. Shots of CYP used to work ok. Scrotal cream was great for a few months then too ramped up. Recently shots with cream was also too much, but...
  13. O

    My Ongoing TRT Mystery

    Day 6 since first Test Cyp injection. Day 1, couldn’t sleep and had anxiety. This week at work I got into multiple arguments with people (which is something that I do not do ever). Shortness of breath has returned. Stupidly took pregnenelone yesterday to try to help. Have had heart palps...
  14. O

    My Ongoing TRT Mystery

    Totally b.s. for sure, but I also don't feel like thyroid is the driving issue and it was probably a one time thing.
  15. O

    My Ongoing TRT Mystery

    I have lemon balm tincture for anxiety, have never tried it yet because well...of my anxiety lol. Stupid I know. How do you feel it works for you? Also have not supplemented vit d yet. I have some 2000iu with k added.
  16. O

    My Ongoing TRT Mystery

    Finally saw the Endo, she told me nothing is wrong and then walked out of the room. Basically a 5min appointment that was meaningless. She told me the ft3 test is never reliable and that is why they only use TSH and T4…fair enough. I got back on Test today. 75mg injection 1x week is the...
  17. O

    My Ongoing TRT Mystery

    Further update, my other labs came in. This is 2 months off of Enclomiphene and roughly 4 months off TRT. Total T 293ng/dl (250-1100) Free T 40.1pg/ml (35-155) No e2, but historically it would be between 12-18 with T at this level, so slightly on the low end. Obviously for a 40 year old...
  18. O

    My Ongoing TRT Mystery

    This reminds me of my first foray into all of this and the STTM forums. They would tell you to take more desiccated and tell people all this stuff to keep cranking up the thyroid hormone. Then they’d say if there were side effects that they had t3 “pooling” and the answer was MORE T3. Then...
  19. O

    My Ongoing TRT Mystery

    Yes, which is an interesting revelation. I previously thought that since stoping TRT and not really going to the gym like I used to, I dropped 15-20 lbs. However, it wasn’t like I was an IFB pro and was walking around lIke some jacked gym monster. Eating has increased and weight is still 199...
  20. O

    My Ongoing TRT Mystery

    Just posting some updates/thoughts as this is my log. Still off all sups and hormones, went to the cryrobank today and had samples frozen. Specimen was all good, and saved 11 vials. So now I can feel safe to go back on TRT (and maybe HCG) and know that I will be able to have kids down the...
  21. O

    TRT induced anxiety and panic attacks can be caused by Monoamine Oxidase A gene.

    I believe all your genetic data is in the 23andMe test, they just don’t provide analysis of all genes. If you plug your raw data into GeneticGenie (free or donation based) or Nutrahacker (small fee) you should see all of your SNPs.
  22. O

    TRT induced anxiety and panic attacks can be caused by Monoamine Oxidase A gene.

    Yes this topic is something I’ve been researching for a bit. If anyone has done Ancestry or 23andme, you can run your data through NutraHacker and see your SNPs. I have both MAO-A messed up and SERT. NutraHacker suggests avoiding all androgens and estrogens and using progesterone. I’m not...
  23. O

    My Ongoing TRT Mystery

    An update on things. labs drawn off everything, three weeks after stopping enclomiphine. These are from over a month ago total test 467 (250-1100) free t 69 (35-155) shbg 32 (10-50) dht 45 (12-65) e2 ultra sensitive 17pg/ml hematocrit 40.6% low hemoglobin 13.9g/dl (13.6-17.5) vit d 18ng/ml low...
  24. O

    My Ongoing TRT Mystery

    Currently off all trt for three months: Total T is 312 (264-916) Free T is 5.0, flagged low The good, less panic, no air hunger The bad- sleep is bad, haven’t had energy to go to gym, just feel a bit flat, no sex drive Obviously I need to be on some kind of TRT, but I am also planning on...
  25. O

    My Ongoing TRT Mystery

    B12 is 692 pg/ml (232-1245) below halfway folate is 14.1 no range but low on the graphic range bar any b complex makes me angry, I’m considering just taking b6 and then adding hydroxycobalamin for b12 I always see that b vitamins are the panacea for all mental health issues, but they seem to...
  26. O

    My Ongoing TRT Mystery

    I would never recommend anyone take benzos unless needed and prescribed by a knowledgeable doctor. I have taken maybe 20 benzo tablets over the last 15 years as a total last resort when having a panic attack. I’ve simply noted the benzo response (sexual function, mood, drive, etc.) as a means...
  27. O

    My Ongoing TRT Mystery

    I’m not sure that field of SNPs is researched far enough to be effective yet. However, I have read that slow comt responds well to HydroxyB12 and also some adaptogens like Ashwagandha. Who really knows though? I know that my b12 and folate are low and that any Bcomplex makes me super angry...
  28. O

    Prescribed TRT scrotal cream at 23

    Like you, I took something similar for a while in college, propecia. Within a week of taking it my erections went to shit, they really haven’t been 100% ever again for the last 20 years. I also had my first panic attack after taking it and have had off and on issues with anxiety since then...
  29. O

    My Ongoing TRT Mystery

    Yes I saw this from Shippen that he had a patient that added scrotal cram who also got too ramped up and once he switched him to inter thigh 1-2x a week it kept dht healthy but in a safe range.
  30. O

    My Ongoing TRT Mystery

    Well this is just odd. I’ve been off and on TRT for almost ten years and about two years ago started to get this “air hunger” feeling where I cant take a deep breath. I figured it was related to TRT but my RBC, Hemocrit, and HGB we’re always within range. I use a CPAP off and on, but even on...
  31. O

    My Ongoing TRT Mystery

    I sporadically messed with low low dose doxazosin, and it did provide erections when mixed with cialis. I also tried flomax which also worked but created significant retrograde ejaculation. The feeling of doxazosin, even at 0.5mg dosage was like an instant cortisol killer (or at least felt...
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