There have been other studies showing that absorption is 3-5x on the scrotum vs. other sites, so this isn’t surprising.
One thing to keep in mind, though, is that their baseline levels were already 500ng/dL so the increase was only 700ng/dL, which would probably be different from someone...
Obviously there will be some peak and trough even with daily injections, so I guess what I’m getting at is whether a higher peak and deeper trough would be more or less beneficial from a receptor sensitivity (and E2+SHBG) standpoint - where both the observed plasma levels from studies and blood...
I remember someone posting on a different forum (can’t find the link now) of increased E2 levels on daily dosing vs. breaking up the same dose into 2-3x/week with T Enanthate. Aromatase activity seems to be higher when the peak and trough in T is eliminated from high-frequency dosing. I also see...
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
