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For me it was definitely DHT. Vitamin B5 (aka pantothenic acid) works wonders. But I have to preload with up to 5g per day when it gets really bad. Then maintain with 1000 -1.5K mg and not necessarily every day. Saw palmetto is another option and it's good for prostate health. Although I'm not...

there's so much confusing and incorrect information here it's kinda absurd. Why are people trying so desperately to make someone take AI's when there is really no need for it? Maybe I am missing something here, but none of this makes any sense. Yes high E2 levels aren't great (maybe even...

E2 levels can be managed without an AI. We were discussing AI usage, not E2 levels. In the same article that was linked above, there are some valuable things that weren't quoted: "There are scientific studies that demonstrate estrogen’s potential beneficial effects to a man’s vascular system...

Sorry, but I am not willing to engage in this pointless argument. Obviously you are not willing to have a civil conversation, if you are comparing water toxicity to that of an anticancer medication. OP's E2 levels are completely within range, perhaps even a bit on the lower side. The study...

First, let's consider the half-life of Anastrazole. It's about 4-5 days. Which means that after 5 days only 50% of the substance is cleared from your body. He's taking 0.5mg on Friday. By Sunday he's stacking another 0.5mg on top of whatever amount hasn't been eliminated yet. So roughly speaking...

Please stop the AI and see what happens. You're in a good range right now... Your T:E2 ratio is about 2%, which is solid. Here's the thing, if you see that your E2 is climbing you can always take the AI to deal with it. But don't take it based on any number. Take it only if you feel...

Good decision, IMHO. As far as DIM goes 200mg should be fine. It's not an estrogen inhibitor, but may help with conversion issues. I'd say there is no need to increase the dosage. As matter of fact consider this podcast/blog. It's pretty good. Episode 59 - don't be a DIM wit! — ATP Science...

8.5 is really, really low. The level of anxiety and panic you describe is quite similar to what I've experienced as well. Please don't listen to anyone who says "it's in your head". No, no and no. It is definitely a reaction to an AI not to mention pretty low E2 to begin with will make you...

I would strongly advise against Anastrozole/AI, especially at such a high dosage. 41 E2 is not that high, there is absolutely no need for an AI here. I don't know why people are so obsessed about any specific number. I believe (and have proven to myself through painful trial and error) that...

It's not just about a specific E2 number and I hope that people realize what kind of an effect a very strong medication like Anastrozole can have on one's system. It's bizarre to me that someone thinks there are no other side-effects to this drug. People can have serious problems from Aspirin...

I've been on TRT for about a year and it's been pretty much a horrible experience. The only time I felt decent was when I first started to use the T-cream. I ran out and crashed pretty hard, for whatever reason the doc and pharmacy messed up my order and I couldn't get the medication for about 2...

I'm just really grateful for all the information provided here. If there's anything to say is that TRT must include E2 management strategies and not just a prescription for an AI. From personal experience I can assure anyone that crashed estradiol levels are one of the worst things you can...

I don't get it. You are not on TRT right now? But have been taking AI? Even if you were on TRT in the past, you should still be on it. Your symptoms might be caused by other things, but you didn't provide the numbers. Also on your E2 what is the actual number from the recent test? And what is...

I'm going to add that it's not permanent. However for me it took more than two months to recover. Maybe I got better physically even sooner, but debilitating depression and anxiety were so severe that I could not come back mentally for a while. I've done everything from hypnotherapy to yoga to...

I know exactly what you mean. My protocol and estradiol crash were so messed up... For two months I was losing my mind, barely able to function. I literally forgot what it feels like to be "normal"... I feel like this was one of the most mentally draining events in my life. I guess in a way it...

Thanks for the response everyone. I feel better that it was most likely my mistake with the timing of the test and will retest properly very soon. Cheers

Well, looks like you have solved the issue. I received a full refund for the late results. Very much appreciated. Stellar customer service. I can't say anything negative here. Yes, there was an issue, but it was handled promptly and professionally. I will not shy away from using them in the...

I think a new thread would be better for this, good sir.

No HCG. Only t-cyp 200mg/ml. I got the tests done while on .4cc dosage. I lowered because we saw E2 high again and free test was high as well. Total T number wasn't on the first test (lab error). When I saw it now I got a little freaked out. Yes, the lab work was done after injection. I...

I was consistently low with all of my markers, except estradiol, which always was on a higher end of the scale just a bit over. My most recent labwork shows really high numbers across the board. My protocol was .4cc every 5th day. T-cyp 200mg/ml only. About two weeks ago I switched to lower...

looking at the scale your E2 is on the low side. many symptoms you describe are similar to low estradiol. i am currently going through the same crap. my T has been up and down my E2 had been up and down, nothing messes with me emotionally and physically as fluctuations in estradiol. E2 has to...

Indeed. I feel you about the patience aspect... When I am told to "wait six weeks and see how you feel", I can't comprehend that. It's not like a little headache or something insignificant. When each day is a mini torture mentally and physically, it's very very difficult to accept that I need to...

Thanks so much for your reply. In a way it helps a little to know that I am not alone in this horrible experience. My Endo doesn't want to accept that I can feel so miserable from TRT and taking AI. I am his most "difficult patient" and he's never seen this kinda messed up conversion before. I...

that is correct regarding 80 -> 60 switch. he said it's mostly to bring the Free T down a little. my E2 was high even before i started TRT, that's why I think I need something else to mange it, because clearly i'm not converting well. So even with lower dosage of T-cyp it's unlikely to go down...

usually my anxiety is not so bad. i do take anti-anxiety meds (trying to taper), diagnosed with PTSD. I started TRT specifically to help me deal with anxiety/stress and everything that stems from that. as I mentioned i felt significantly better during my first 2-3 months of the protocol. since...

I completely share your point of view regarding AI. However I do believe that if used properly it can be helpful. I took way too much in the past. That's obvious. But if I take a smaller dosage now, I don't think it is a guarantee that I will crash it again. I can't rely solely on the...

I just got off the phone with my endo. His suggestion was to lower T-cyp injections to .3cc every 5th day (.4 lower to .3). He also said that it's possible that my symptoms are due to high Free Test and not necessarily E2 only. He wants me to take a low dosage of AI. I'm scared, honestly...

what's going on now is that i'm injecting .4cc T-cyp every 5th day. my numbers as of two weeks ago (i don't have anything more recent): Free test = 38 (Range 8.7 - 25.1) High E2, sensitive = 58 (8 - 35) Higher than before SHBG = 59 ( 16 - 55) High, but looks lower than before i feel better...

I started TRT using lipo compounded cream in May of this year. at that point my E2 was a little high 32 (> 29) using QuestDiagnostics scale. My endo gave me 1mg anastrozole to take 3 times during the 1st week, and then 1mg once a week. In total, I believe it was 14mg over the course of 4-6...

I bottomed out my e2 two months ago. I stupidly took prescription dosage of Anastrazole (total of 2g) over the course of four days. I am still not recovered. The constant roller coaster is very familiar. Last week my libido was up and I was having sex every day. Last few days I can't even feel...

Be very careful with AI, too many horror stories, including my own regarding crashed E2. If you think high E2 sucks, you will be in for a rude awakening with low/crashed E2. Please seek out other ways to lower your estradiol. AI should be used as an absolute last resort and in tiny dosages...