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  1. J

    FSH stimulates aromatization

    My best option is testosterone, 75-90 mg per week, plus 250 IU of HCG twice a week. But since fertility is my main goal, as soon as I take more HCG, I experience a decrease in libido and erections (even when maintaining testosterone). I've learned to live with this thanks to PDE5 inhibitors...
  2. J

    FSH stimulates aromatization

    We're both on a similar journey. I'll be getting some lab work done in the next few days. I think I'll probably need to reduce the HCG to 500 IU M-W-F (if the E2 is still that high), while maintaining 150 IU FSH, then recheck after a couple of weeks. Goal: lowest HCG dose possible while...
  3. J

    FSH stimulates aromatization

    My Conclusion: If you are undergoing fertility treatment with HCG (Monotherapy), AND with the addition of exogenous FSH, the latter makes testicular use of testosterone more effective, therefore you need less HCG to obtain the same or better result, while higher doses of HCG (or FSH) produces an...
  4. J

    FSH stimulates aromatization

    Significant association between elevated circulating estradiol and larger prostate volume in adult men Implication: Hormonal imbalance can drive prostate enlargement https://www.healthline.com/health/advanced-prostate-cancer/role-of-estrogen-in-diagnosis?utm_source=chatgpt.com
  5. J

    FSH stimulates aromatization

    Estrogen and Spermatogenesis Liza O’Donnell , Kirsten M. Robertson , Margaret E. Jones , Evan R. Simpson Endocrine Reviews, Volume 22, Issue 3, 1 June 2001, Pages 289–318, https://doi.org/10.1210/edrv.22.3.0431 Published: 01 June 2001 Cite Permissions Icon Permissions Share Icon Share...
  6. J

    FSH stimulates aromatization

    Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis - New Insights Myles Leavy, Matthias Trottmann, Bernhard Liedl, Sven Reese, Christian Stief, Benjamin Freitag, John Baugh, Giulio Spagnoli & Sabine Kölle Scientific Reports volume 7, Article number...
  7. J

    FSH stimulates aromatization

    Sure! But... any amount? Does it matter how you feel, or should you be happy just for a high estradiol level, regardless of how you feel? Is it equivalent the (disruptive) amount of exogenous hormones you inject into your body, to the natural physiological and hemostatic adjustment? Fine tuning...
  8. J

    FSH stimulates aromatization

    I've been on HCG monotherapy for a while now, and my response has been much better lately than it was years ago. E2 has always been an issue with HCG. In a recent lab, my TT was over 1000 ng/dL, while my E2 was around 65 pg/ml. I tried to control my E2 by alternating 780/500 IU of HCG EOD...
  9. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    No Pelvic MRI but ecography. It turned out completely normal, not even significant prostate enlargement for my age. I don't think it is obstructive, but hormone dependent, it was clearly related in time with clomiphene use. But age is playing a role here for sure... :( The pain I'm referring...
  10. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    I took HCG mono 500 IU M, W, F, about two years ago. I wasn't feeling well; my testosterone level was 520 ng/dL, E2 48 pg/ml, and I had low libido and severe erectile dysfunction. I then increased the HCG dose to 1000 IU M, F, and felt worse; my testosterone dropped to 420 ng/dL, E2 58 pg/ml...
  11. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    My sperm volume used to be normal, between 2 and 4 ml. It dropped dramatically after a failed attempt to a restart with clomiphene, during which I stopped TRT and HCG and only used clomiphene, 25 mg EOD. I dealt with all the symptoms of hypogonadism, thinking it would only be a matter of time...
  12. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    My blood sample was taken on Friday morning before the corresponding HCG dose for that day and 48 hours after the previous dose. I think the only way you have to know your level 24 hous later is testing it.
  13. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    hi, @madman , Thank you for your evaluation. The truth is, I don't have access to more accurate tests. What I value most are the symptoms and how I feel. I used to have problems with HCG (I don't have problems while on testosterone alone), but not this time. I'm still waiting to see how long...
  14. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    Update: during the last month HCG Monotherapy dose (Ovitrelle) has being 790 IU M, W, F. with Anastrozole 0.25 mg M,W.F. HCG has always been a nightmare for me regarding libido and ED. This time is completely different, I have great libido, and ED has improved dramatically, almost no need for...
  15. J

    22 yr Old Low E2, 0 Libido

    You are very young, don't let atrophy your testicles, I would advise HCG 500 IU 3 times a week, along your trt and may be a lower dose of Testosterone (HCG monotherapy could be even enough for you). With HCG you will probably solve your E2 issue, have good testosterone level ans stay with...
  16. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    For me is like that: (As a general rule but not always) shot day: transitory libido boost about 3 hours later. Second day: low libido, may need bigger dose of pde5i. 3rd and 4th days: bigger and sensitive testicles, better libido.
  17. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    Here is where the other questions play a role. Age, how long you have been on Trt, which involve the capacity of your testicles to respond, etc. It makes sense to start low, ex. 500 iu, wait and check labs, adjust dose, add complementary (Ex Ai, cabergoline), check again and so. Through the last...
  18. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    It is also known that testosterone itself impairs to some degree the action of hcg at testicular level by inhibiting an enzyme involved in the production of endogenous testosterone, so it is always better hcg alone for its maximum effect, valid especially for older men and those with longer...
  19. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    Intratesticular levels does not correlate with blood levels, then, just to attend testicular health, you need lower hcg doses as you mention, but you may need to add exogenous testosterone for your complete wellbeing. If not testosterone, then you need higher doses of hcg to use it as...
  20. J

    HCG DOSE FREQUENCY FOR MEN - FERTILITY & TESTICULAR ATROPHY

    The answers depend on the scenario and goals. Want fertility or just avoid testicular atrophy? HCG monotherapy or along Trt? Age? How long being on trt? And more.
  21. J

    Cypionate to Undecanoate conversion schedule (100MG)?

    I don't see the need for that. Just take your first dose of a full vial of undecanoate; it will rise as the cypionate wears off over 3 weeks. Then, continue with your desired undecanoate schedule.
  22. J

    Was Excel Hacked?

    Same here.
  23. J

    Has anyone successfully kept Hematocrit/Hemoglobin low without donating?

    At the beginning of my TRT I had to donate blood very often, then my hematocrit stabilized and I have now gone approximately 5 years without needing to donate.
  24. J

    Does Monogamy Work? (Watch if You Value Your Relationship)

    "Does Monogamy Work? (Watch if You Value Your Relationship)" As humans, we were created to have monogamous relationships, it is the only way we can form healthy families, healthy offspring, and pass on the values that made us superior to animals both intellectually and spiritually. Individual...
  25. J

    Testosterone plus Clomid Combination

    I don't think Clomid increased any LH and FSH level on you, but it may work by helping HCG at testicle level, counteracting the effect of excess of E2.
  26. J

    Clomiphene citrate: A potential alternative for TRT in men with low testosterone

    I would like to say that care should be taken with long-term treatment with clomiphene when there is no adequate LH response so testosterone remains in a very low range. That was my case, and I persisted for 6 months waiting for LH and testosterone to rise to a normal level, IGF-1 dropped...
  27. J

    My labs on 16mg every other day Test Cyp

    Yes, for me Insulin Syringe, 26G x 12.5 mm, into deltoid and outer part of the thighs. When on thighs, I press deeply with my fingers over the skin while inserting the needle, do to avoid doing subQ.
  28. J

    My labs on 16mg every other day Test Cyp

    Same happened to me when I tried SubQ. Then I went the Shallow IM route, and worked wonderful. I could do Shallow IM every day, for me it is almost painless, and less likely the have bruises or any other side effect in the site of injection.
  29. J

    HGC -- off for a week, suddenly morning wood

    My experience is that there must be something more to HCG killing erection (and libido, depending on dosage) than just E2. I have been on an odyssey for almost 4 years with HCG (and sometimes Clomid) trying to get my wife pregnant while battling very severe ED and loss of libido as a result of...
  30. J

    TRT & Pheromones (Question for the Ladies, Especially)

    I haven't read any studies on this topic, but from personal experience I believe that pheromones depend on testosterone itself, or its synthesis in the testicle. When I first hugged and kissed my current wife, about 4 years ago, she tells me that she was caught by my scent and despite it being...
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