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THanks for the feedback. Why only once a week with high SHBG? My doc said that once a week dosing lead to too much up and down of testosterone levels. Also, I've read some papers (on pub med) suggesting calorie restriction raises SHBG. What if that was a fluke lab?

Hello, I recently began TRT at 49 with symptoms of apathy, fatigue, night sweats and low libido. I had the following labs TT 669 E2 17.6 SHBG 116.4 mol/l (reference range 16-55) The calculated free T was 5.34. All other hormones (thyroid, FSH, LH, etc) were normal. The doctor put me on Test...