Search results

We need more data but from my write up "...As creatine is an essential molecule in energy production for all cells, it also acts as “molecular battery,” wherein stored energy helps these essential immune cells from simply running out of steam to fight on." The “molecular battery" aspect no...

As always, risk/benefits exist. There's data to suggest creatine made cancar therapy more effective for example: https://brinkzone.com/creatine-as-cancer-fighter/ This is from a recent review also: Does creatine cause kidney damage/renal dysfunction? Questions and concerns involving creatine...

I do have a contraindication write up on creatine below. Elevated creatinine is not in itself an issue, and we know creatine is not "stressful" to the kidneys, but should not be ignored either. If it's elevated while on creatine, take a few weeks off, make sure to be well hydrated, and re test...

Hence the creatine graveyard, where various forms of creatine not CM go to die: https://brinkzone.com/the-creatine-grave-yard/

You won't give her thrush but you might cure it. I kid.

Tell me you didn't read the article without telling us you didn't read the article...

As COVID-19 is the current topic, I have condensed and updated my lactoferrin discussion specific to anti-viral effects of lactoferrin: 20 years ago (how time flies!) I wrote about the impressive anti-viral, anti microbial, anti caner, immune supporting effects of lactoferrin via Life...

Bump, In celebration of my up coming novella "Old And Angry" I have made part I of my highly rated Vacation Gone South series FREE today if interested: https://www.amazon.com/gp/product/B00VPC7PPK/

A great example of why MDs should avoid giving nutritional advice as if the estrogen source from BC was the same as what's in soy. The bottom line is really the same: While I'm no fan of the Impossible Burger. It's complete nonsense. Same rules apply for all fast foods: occasionally is fine...

It's a good vid, but one really has to read between the lines of what she's saying, and she's not actually saying no one should take statins. Over prescribed, yes, possibly not as effective as some studies suggest, yes, and side effect profiles may be higher than reported, yes. She's not...

Good to hear! That's more as it should be in terms of which speciality should be up on the topic of TRT/HRT.

I'd harden a bit and say most endos truly suck at TRT/HRT. For what ever reason, Urologists tend to be much better, and even most internests, GP, etc are better at it. Knowledge of hormones is supposed to be their damn speciality, and to date, not met an endo who didn't outright suck at it. No...

Correlations are almost always what leads to understanding/discovery of mechanistisc pathaways and causation factors. All of the risk factors you're aware of were discovered via epi/correlational data. It's very difficult to do meaningful tghtly controlled RCTs in free living humans and CVD for...

In short, lipid levels still correlate to CVD. The moving target is which lipids, trg/LDL ratios, particle sizes and ratios, various confounders, etc. There's obviously other risk factors unrelated to lipid levels that dictate CVD or not, some of which we have control over, some of which we...

1, maybe, and worth trying, but genetic component rules all 2, try it and see what it does for your lipids, and proceed from there. Obviously, make sure to supplement CoQ10.

I agree with that assessment. Statins have a place and are of value for some. Over prescribed? Yes. But, few willing to do what's needed to improve their lipid profiles, and for some, there's a genetic component damn near impossible to improve. Docs, etc I trust feel statins are of value, but...

Demonstrating yet again, creatine works. :cool:

Seeing a therapist, cognitive therapy, meditation, exercise, sex.

Due to the influx of Qs and comments about the faux documentary The Game Changers, I have posted some comments and links to excellent reviews for those who want the facts: This is not going to be a review of the recent faux documentary The Game Changers per se. As others (linked below) have...

Covered somewhat in my article. There may be new data since I wrote it, not sure. Due mostly to cost combined with lack of useful human data, I don't use NR myself currently.

A good Q, and that's just it: what are the measurable endpoints demonstrating actual benefits? That remains unclear. Majority of the data is under the low tissue levels of NAD+ are associated with X bad things so raising NAD+ levels back to that of younger people will prevent bad things/teat bad...

500mg would probably be seen as min dose. You can get NR less expensive from LEF and some others I think, but it's still overly expensive in my view. That's not the fault of the companies selling it BTW, the major seller of NR (ChromaDex) with patents charges way too much wholesale for it...

Seems all over the place and no doubt, over priced considering costs of materials which is not high. There's some data to suggest NR may be superior to actual NAD+ for entry into the cell and an increase in NAD+ and some doing NR infusions also. Oral NR may be adaquate for increasing NAD+ tissue...

What were you taking? NAD precursor NR?

Use it rarely, but 25-50mg worked fie for me. Accidentally took a 100mg tab and it gave me a big headache and racing heart and was not fun at all.

That's what I figured without digging into it.

Would you see normal creatinine levels yet elevated Cystatin C Levels? That is, if creatinine is normal, would there be any reason to also do Cystatin C Levels? I'm assuming the answer is no.

Good find! Had another doc claim he didn't recommend creatine due to "renal stress" just the other day. Astounding such mythology will not F-ing die!

Yet another potential benefit of creatine is that of an essential immune support supplement via energy for antitumor immunity. While this is a mouse model, there’s no reason to think it does not apply to humans as the cellular mechanisms are essential the same: “...our results have identified...

That's not even a high dose by female BBing standards (sadly), so I don't get that comment. Off season T use by BBers is as high as 1G per week, combined with a variety of other AAS, as well as other PEDs. None of the bbers I knew/worked with used less than 400mg per week, combined with multiple...

Great, thanx! Will order now.