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Update for all: I finished my 30 days of tamoxifen then I ran bloods immediately and My LH was 14.4 (Wow). FSH was 11.7. Testosterone was 559ng, Free was 53.5 pg/ml (range 46-224), E2 sens was 20pg/ml (more on that below) Been off tamoxifen for 2 weeks now. Been off Trt for 51 days now. Major...

Hi Dr. John, (or another expert) Coming off trt now. Was on 50mg E3.5D for 5 months with .125 AI E3.5 Days. I'm 10 days from last 50mg T-cyp shot. Very sensitive to any E2 over 20. Using 10mg tamoxifen per day for 6 weeks. Was advised to keep taking .125 Anastrozole every 3.5 days for this 6...

Thanks much BigBamBoo. "This too shall pass" is one of my favorite sayings when under stress. I'll let you know how it's going occasionally:)

Any input guys?

I'm going through the HPTA restart right now. I'm only 11 days off my last shot (50mg 2x week). Per defy I'm using tamoxifen 10mg for 6 weeks. I too had many issues that I could not resolve. But I must say if I ever tried again it would be with Defy. Good people. When should I expect my...

Hi Guys, I'm getting off TRT to possibly get my wife pregnant. I also have struggled with anxiety a lot while on trt. My question is do I need an AI during my 4-6 weeks of tamoxifen? I am very sensitive to E2. While working with defy we figured out that I cannot be over 15 pg/ml (sensitive...

I just talked to Nurse Sarah from Defy Medical. She is putting me on 0.125mg Arimidex 2x week asap. She was so kind and concerned. That goes a long way when we're suffering :) I'm also going back to my 50mg E3.5days of T-Cyp per Sarah. The anxiety was getting so bad I thought I might need...

Welcome and good luck Chris!

Yes Thank you Vince. My SHBG is 43. But I swear this feels like the way you guys describe high E2 symptoms. I will also run the Free E2 test you mentioned. In my consult with Dr. Saya I think he said it was possible but I forget. And another member mentioned that there are some studies...

Is it possible to have high E2 symptoms without E2 being very high? My E2 is 30pg/ml on the sensitive test and I have all the symptoms after my shot and the next day/days. Symptoms like: Bloated, puffy face, irritated, anxious, Angry (especially hours after my shot), headache, waves of...

Hang in there :). Many get it dialed in. Vince Carter has low SHBG and has posted a lot of great info as you may know. It really stinks at times getting it dialed in. I'm going through it too. I track my mood with a basic score 3 times per day so that I can reflect on any improvements...

Thanks lowe2. Very interesting. "adaptive hypersensitivity". I took another DIM tablet after my first 28mg T shot via new protocol because I started becoming angrier by the hour. Not my normal self. I'm hoping it will level out over the next 5 weeks. I notice this wind up after each shot...

Ok Guys, I had my meeting with Dr. Saya from Defy Medical. I can't say enough good about him. I don't know if this TRT thing will pan out for me or not (praying it will) but he is the right Doctor for sure. He's very smart, kind and humble. A real decent man. He suggested that I start EOD...

Maybe I need to re think my 40mg lipitor? Could it be harming more than helping? I have good numbers now...

Hoping and praying for you too!

You are at the right place to learn. Good Luck!

Your body is going through major adjustments. Give it some time. I lost my libido (low) for a month. Now it's raging again. I would hold off as long as possible on the AI. But if your body cant readjust through it for a few more weeks you may want to retest E2 and then decide from there...

OK I will. Thanks

Is my TSH at 4.19 a problem?

Mark: Thanks a million for your thorough reply! I just got in late from traveling but I will re-read carefully. Thanks again :)

Above 50mg it did. Below that not much. But I have a natural proclivity to be over sexed so 50mg curbs the ridiculous sex drive but still good and functional...25mg it goes into overdrive but then less effective for anxiety etc. But we all react differently.

Thanks Moogie! I'm not opposed to an AI if I really need it. Maybe I do. Like you said, maybe I can drop it later if I lose 20lbs...

Hi Guys, Would really appreciate some input/advice :) Here is my first blood (taken just before injection) lab work on my latest 7 week protocol of 50mg Tcyp 2x per week. No AI or HCG yet. Been on TRT for 13 weeks. I have an appointment with Defy soon but I was looking for input. Please...

It's way to individualistic to determine from what I've learned.

I'm so happy for you! It's interesting how too little of HCG was worse than more HCG. You know it's a chemical imbalance when there is nothing to worry about but you still have the anxiety for no specific reason. If my protocol enables me to remove my zoloft I certainly will. Do you take an...

@Mission: How are you feeling with your protocal?

Yes but subtle

I take 100mg per day and 200mg on shot day. That's just me...

Ken I take a very low dose zoloft (50mg) with trt. And I use gabapentin at a small dose for the anxiousness caused by zoloft (and it helps with anxiety). My vote would be to stay on trt and take the zoloft. Why fight your brain if you have a chemical imbalance. I tried to get off zoloft and...

Everything but the kitchen sink :eek:

I'm always curious how someone feels before changing their protocol. How are you feeling?