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Thank you Vince. I really appreciate that !

Thank you so much for the effort you have put in to explain my question. So what i have gathered from the articles is that both high frer testosterone and estradiol are linked to high BP. Is it also trur for men like me who are on TRT. I have high frer T 55 pg/ml reference range 8-28. My...

Will you explain why high Estradiol is related to high blood pressure? This will solve my confusion !

I am having a throbbing heart rate since many days. I have tried to search for an answer and the only definite reason is high estradiol. I have low shbg 14.5. And Free T at 55pg/m (8 to 28). Total T is 979. I am on 17.5 mg EOD. So there is no obvious reason except that its high E2. Which is 55...

Hello Sir, I have great respect for your work that has helped thousands of newbies like me. I would like to use your knowledge further. Please explain why elevated Estradiol levels causes high blood pressure? I have searched this topic with no specific answers.

If i have to phrase my question in other words. Why high estradiol causes high blood pressure? I tried hard over the internet but couldnt find a definite answer.

If Hematocrit and Hb is fine, RBC is slightly over the maximum. Would blood donation still help in lowering high blood pressure?

Yes i will keep my doctor in loop for sure. So you are suggesting for daily injections. I will definitely think over it. But for now do you think reducing 17.5 to 10 mg EOD is a good idea? If that doesnt work, daily injection would be the best option. What do you say?

@sh1973 First of all Thank you very much for your responce. I was really confused. I am planning to swtich to 10 mg EOD instead of 17.5 Do you also have low SHBG? How many times you inject per week? Are you on EOD protocol?

So i have low SHBG 14.5 nmol/l. I am on EOD protocol 17.5 mg Test E. I was doing pretty good but after 8 weeks of running this protocol the lab reports telling that i have insanely high levels of Free T 55 pg/ml(8 -28). The Total Test value is also very high 979 ng/dl. The E2 being at 54 pg/ml...

@blackhawk i have low SHBG. I am on 17.5 mg EOD. How much should i reduce my dosage to get rid of the sides?

I wish i had that facility. The E2 sensitive test is not available in my country. What about the high Free T issue?

My hematocrit is fine. Its 47.5.

Hello respected members, My age is 31 years and i have just completed 5 months of my TRT. Its been a struggle from the very start because i am a low SHBG guy(14.5 nmol/l). Previously I have tried different protocols like, 50 mg E 3.5 D Labwork T =721, E2 =42(non sensitive) 60 mg E 3.5 D...

But my question still remains the same. Pre TRT total test of 250, SHBG 19.8. This is by any means low SHBG > more free Test. So why i had low T symptoms pre TRT with high levels of Free T? Please also explain your Albumin and Estradiol point in relation to my question.

@systemlord But my question still remains the same. Pre TRT total test of 250, SHBG 19.8. This is by any means low SHBG > more free Test. So why i had low T symptoms pre TRT with high levels of Free T?

When i started my TRT my initial total Test were 250-300 ng/dl and it was giving me classical low T symptoms. At that stage i had an SHBG of 19.8 to start with ( TRT lowered it to 14.5). But the confusion here is that when i had 300 total test before TRT i still had low T symptoms, BUT my SHBG...

I am also making up my mind for EOD injection. The confusion seems to be vanishing as soon as i started getting replies from experienced veterans ! Thankyou!

I have very low SHBG 14.5 so i have more free E2. I have read a lot of low SHBG guys doing well on low E2 levels because they have more free E2. So do you still think that raising E2 is a good idea with respect to me very low SHBg?

I can not thank you enough for your guidance. I am now coming closer to the following conclusion : a) i should be injecting EOD b) With a SHBG of 14.5 my maximum dosage should be not greater than 20 mg EOD. I have question regarding your following point " Whenever you move injections closer...

I am 31 years old and 12 weeks into TRT. Please help me as i am really confused and stuck after my low shbg test came out last week. I am just kind of stuck at 12 th week. Seems like so much things revolving in my head at this stage. So it is best if i give you what i have done so far. I had...