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  1. S

    Levels normal but PROLACTIN off the CHARTS.....

    Strum: for men on TRT (testosterone replacement therapy) I want to suppress prolactin (PRL) and this is easily done in 95% of cases with very low dose cabergoline, such as 0.25 mg three times a week and then recheck PRL after a couple of weeks. Once in a while I need to up to 0.5 mg 3x a week...
  2. S

    Ask Dr Rand McClain

    Good morning Eudes, Re the aromasin dose, I would use half tablet twice a week (abbreviated biw) and recheck the estradiol (E2) level and keep below the lower limit of normal (usually 40 but depends on the lab). If the level is still high, I would ↑ the dose to three times a week...
  3. S

    What do you do when your estradiol is too high

    I have used a lot of aromatase inhibitors in my medical practice. First of all, anastrozole (Arimidex) or exemestane (Aromasin) are for me about equivalent. I just use Arimidex more because more pharmacies seem to carry it. My patients on TRT (testosterone replacement therapy) often require...
  4. S

    new to trt

    Strum: what I find in my medical practice involving men that are either getting ADT (androgen deprivation therapy) or TRT (testosterone replacement therapy) is that most physicians do not obtain baseline lab results, do not monitor changes over time, often forget a major dictum (Above all do no...
  5. S

    Ask Dr Rand McClain

    Strum: your English is fine. Again, I hope I did not break any rules with my input here. Stephen B. Strum, MD, FACP Medical Oncologist
  6. S

    E2 Levels in Healthy Young Men

    Not exactly sure what you are asking but in any man, if there are high T levels or a testosterone surge it is fairly routine to see aromatization of T to E2 (estradiol). And that is not something you wish to ignore since estrogen will stimulate prolactin production (PRL) and PRL has many...
  7. S

    I would be really grateful for any help understanding my blood test results.

    I am a MD, focused on prostate cancer but well versed in the endocrinology of male hormones. A few points, in no particular order. Your TSH of 3.5 does not indicate you are definitely clinically or even biochemically hypothyroid. First, we need to know the normal range which you said was not...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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