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Interesting, thank you for the reply. My only concern wouldn't taking kisspeptin and GnRH at the same time possibly stimulate too much gonadrotropins and thus possibly act as the opposite? From my understand GnRH at high dose can be used as chemical castration. I guess the dose is the thing...

That's not why its called kisspeptin, the scientist that found it lived near a hershey factory and named it after hersheys kisses...they didn't understand how significant it was going to be at the time so was a bit of a joke.... But anyways it is suppose to increase libido from research I've seen.

@Nelson Vergel Hi Nelson, in the conclusion it says "Furthermore, kisspeptin reset the GnRH pulse generator, as it not only induced an immediate LH pulse but also delayed the next endogenous pulse by an interval approximating the normal interpulse interval." Am I understanding this correctly...

Hi madman, thanks alot. Have you been able to get it shipped to Canada? I regularly order from iherb for supplements but for some reason I thought they wouldn't ship to Canada for preg & dhea due to regulations. I see I can add it in my cart when before I couldn't even see it. EDIT: looks like...

Hi, I use to get my preg from dhea.com and still get my dhea from there but they discontinued pregnenolone unfortunately. They packaged things well for Canada and never got it seized. Wondering if anyone has had success with another company shipping to Canada(specifically for a micronized...

I have a bunch of alpha GPC as well as other nootropics but the only thing that concerns me is that so many in the nootropic community report feeling depressed with continued use of alpha gpc. While trying to dial in my trt not sure if it's a good idea to try this at the same time(as won't be...

Interesting Dr. Crisler. I'm wondering if there was an adjustment period for you? Like felt bad for first few weeks but then things got better or was the benefits apparent from the get go? Thank you

Interesting. From my understanding the side effects of rising hormones(anxiety, depression, emotional etc) can take a while to stabilize. I believe Dr. Nichols said to give it at least a month and go through the side effects and everything should be better after. I switched my protocol after...

I thought so too. Enough for me to let my estrogen rise naturally and see what happens.

Not sure how your comprehending this from my comments: 1) I'm not clinging onto anything, this is a discussion on not using an AI, Dr. Rouzier has a very convincing presentation that seems well backed on science on why not to use an AI and the BENEFITS of elevated estradiol. I don't know what...

I'm just reporting what dr rouzier said, he said these 2 dozen or so men take 2 to 6 mg of oral estradiol dsily with testosterone and only see benefits, it's in the last 15 minutes of interview

Guys if you listen to the whole thing Dr. Rouziers rntire point, from my understanding, is more estrogen the better. The method of testing is really moot at this point when he says things like most are several times over reference range, with 2 dozen doctors themselves in the 200 to 300 range...

Jay just put up an interview with Dr. Rouzier and near the end of it Dr. Rouzier says that some doctors are even experimenting(On themselves, not patients as far as I can tell from that convo) with ADDING estrogen with testosterone therapy to bring E2 in the 200+ range which according to him...

Very interesting data, I've seen before too that aromasin 25mg = 1mg tab arimidex but I've never seen data to back it up and your numbers are almost identical for e2 so thanks for posting that! The lowered SHBG but same free E2 and free test is also very interesting, and confusing! Out of...

So just got back iron, cbc and thyroid results: These are Canadian values, some are the same, some are different so I included reference ranges Iron 22 (ref: 7 - 29 umol/L) TIBC 59 (ref: 45-77 umol/L) Ferritin: 75 (ref: 24-453) T4 FREE: 14 (ref 12-22 pmol/l) T3 FREE: 5.1 (ref 3.4-5.9 pmol/l)...

Thanks for the reply. I had originally taken a higher dose as I wanted to be in the upper range, I can lower it again but my SHBG is 42 not 18, that's another reason why I thought a higher dose might work better? Good point for HCT, I did bloodwork a few days ago for iron panel, cbc and a few...

Hi FeelingLost, The testosterone dose I adjusted about 4 weeks ago, shortly after my first post on this thread. The DHEA/Preg I started yesterday. Regarding high E2 signs I can't notice anything that's really changed since my low e2, to medium to now - all feel's the same. (libido is still...

Hey guys, Here's an update on my progress: I increased my dose to 140mg a week(split in two shots) and added in 20mg preg and 20mg dhea per day. Just got back my estradiol sensitive test, it's at 37.4 , I'm guessing the increase is because this is after almost 2 months of NO ai and increase...

Thanks for all the replies. I have an appointment on Monday for the sensitive estradiol re-test. Talked to my GP and said it could take month's to get in for a new endo so I found a naturopath that specializes in thyroid disease that looks on top of things. I'll see what she has to say, I might...

Yes I agree, I've brought this up several times and it's always been dismissed.I was pretty brain fogged and tired when this all started and I should of took more charge but I trusted this doc(unfortunately), time to find a new one as it seems everything has been stalling for over a year now...

I live in Winnipeg, Manitoba. The endo I'm seeing is apparently one of the top ones but I've had a miserable experience so far and talking to other people that see's her they all say the same thing. Not sure how to find a good one though as I believe I need a referral from my GP to see an...

that's interesting, I didn't know thyroid could cause those problems. My doc refuses to test rt3 for some reason and will rarely test t3 across the 2 years I've been seeing her. She also refuses to prescribe anything then synthroid which is frustrating. Looks like I need a new doc for that...

Hi madman. Thank you for detailed response. Regarding naturopath I can only see my endo every 3.5 months due to his busy schedule so I want more tests in between. Also when I brought up the sensitive estrogen test he laughed and said there wasn't going to be a difference. Need to find new...

Hi Systemlord, I do have hashimoto's but I've been dealing with that for years and all my thyroid values are in the optimal range as of 2 months ago, have another run of tests in 3 weeks from now but my levels have been consistent for a while now. (TSH 1.4, free t4 in upper range, antibodies...

Hey guys, Please see below for my blood test results, not sure were to go from here. Symptoms include 0 libido, ED, brain fog and fatigue. I'm Canadian but I translated the values into US one's to make it easier for everyone. Total Testosterone: 735 ng/dl (25.5nmol/l) Free testoserone: 495...

Hi Vince, I just started a similar stack to you. Thanks for the bulksupplements recommendation btw, saved quite a bit of money ordering in bulk compared to ordering smaller containers on Iherb. Do you find the stack has an acute effect or cumulative? Just started a stack of(twice a day)...