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  1. Reason

    Anyone ever tried nattokinase to lower hematocrit?

    I'm trying it. Started about a month ago. Let's see...
  2. Reason

    I Haven’t Slept in 4 years. What to Do?

    Would a PCP or GP be amenable to prescribing Hydroxyzine for insomnia or should I ask my Psych?
  3. Reason

    I Haven’t Slept in 4 years. What to Do?

    Thank you for the detailed response, @wondering. I will look into HC. I did a thyroid panel early 2020 and a few months ago, did a ton of research to read them and consulted with my Defy doctor. It's not an avenue I'm interested in pursuing anymore. Interestingly, I have been able to sleep...
  4. Reason

    I Haven’t Slept in 4 years. What to Do?

    High E2 really disrupts my sleep, so I use an AI as needed, but just taking the pill has no immediate effect. I used to do edibles because they last longer and kept a vape pen on my bedside table in case I woke up anxious in the middle of the night. Would take a small hit and went right back to...
  5. Reason

    I Haven’t Slept in 4 years. What to Do?

    I've never tried hydrocortisone. Can you explain? Thyroid is normal-to-optimal, did a full panel last year. Pandemic ruined my exercise regimen, but I've been lifting for years. Definitely helps, but not a cure.
  6. Reason

    I Haven’t Slept in 4 years. What to Do?

    First of all, I'm really sorry you're going through this and hope you've found some help. I haven't had good (natural) sleep at any point in my life for a consistent amount of time. I'm 40. Spurts of 6hrs/night here and there. I probably with physiological/neurological delta-wave disruption or...
  7. Reason

    Fatigue, anger, swollen ankles, etc.

    Wow thank you for taking the time to respond and share what you've found out so far. I really appreciate it. I'm not too worried about the water retention quite yet, it comes and goes and it's mild. What made me consider it was the possibility it was related to the other symptoms and it could...
  8. Reason

    Fatigue, anger, swollen ankles, etc.

    Fatigue/feeling out of breath subsided after a phlebotomy. Anger/volatile emotions subsided by going back on a daily regimen and reducing my overall weekly dosage to 119mg. Ankle swelling still present...
  9. Reason

    Nootropics: Qualia

    I tried it. It's incredible. I keep the rest of my bottle on hand for specially busy weeks. But I stopped it because I don't intend on being on a cocktail of supps for the rest of my life.
  10. Reason

    Need help with sleep management on TRT

    CBD, besides being an anti-inflammatory, is also an anxiolytic. If CBD has helped your sleep measurably, it might be worth considering lowering stress and other forms of mental health improvement like exercise, therapy, etc. so you don't rely on supplements long-term. I know for me, I can take...
  11. Reason

    Does Sleep Apnea Cause Elevated Hematocrit?

    I second what fifty said about sleep places pushing CPAP. This happened to me about 5 years ago. If your insurance covers it, by all means give it a shot, but it's incredible how quickly they push you palliative devices without even looking at underlying causes.
  12. Reason

    Need help with sleep management on TRT

    Klonopin is a benzo and shouldn't be used regularly.
  13. Reason

    Therapeutic Phlebotomy Places in the United States for Men on TRT

    112mg Cyp/week (16mg daily). I'm due for labs in about a month, haven't checked since I started CPAP. It's likely it will help some, but HCT has consistently gone up since I started TRT so I don't think apnea is the culprit.
  14. Reason

    Therapeutic Phlebotomy Places in the United States for Men on TRT

    I ended up finding a mobile phlebotomist/lab that services the Bay Area but they're quite pricey and I suspect this will be a 2-3x/year thing for me. My Kaiser doctor is not cooperative. His response is I should stop "this aggressive hormone treatment." It's the 2nd Kaiser doctor that has...
  15. Reason

    Therapeutic Phlebotomy Places in the United States for Men on TRT

    I live in San Jose and spent hours on the phone and can’t find a place that does phlebotomy... Can’t donate because I visit Brazil yearly and the area is marked as risk for malaria (ludicrous, but the CDC is paranoid...).
  16. Reason

    Need help with sleep management on TRT

    Magnesium Bisglycinate, 400mg/day split into 2 doses.
  17. Reason

    Fatigue, anger, swollen ankles, etc.

    20.2, was 34 before treatment, has consistently gone down with every test.
  18. Reason

    Fatigue, anger, swollen ankles, etc.

    I'm currently dealing with a few things that may or may not be TRT related. I scoured these forums to see if I could find help with no conclusive answers. Background: 38, 5'11", 205lbs TRT since Feb 2018, currently 138mg/week (3x) + 500IU HCG (2x) + .125mg Anastrozole 2-3x as needed DHEA 25mg...
  19. Reason

    Need help with sleep management on TRT

    I had the EXACT same issue. Still get it once in a while but my current issue is waking up too early. Some of what I'll say below is for the benefit of other forum members with sleep issues as well. I'm a lifelong insomniac currently getting OK sleep after a horrendous year. What has worked for...
  20. Reason

    Sex drive and semen

    Just want to jump in quickly with my personal experience: TRT since February (T-Cyp + HCG) Jump in libido/function in first 30 days, "honeymoon" Decline after, lower libido, fatigue, function was meh Found out my E2 was sky high (60+) Added AI Back in business! Libido great, function could be...
  21. Reason

    Recent labs: HIGH Estradiol. Causing sleep issues?

    Quick update: After adding an AI, issues improved a lot but sleep still bad. Just got labs back and my TSH, FT3/FT4 levels are either at or near optimal. T, FT, and E2 are still high so I'm planning on reducing my dose slightly. I've a follow-up consult on 07/05, we'll see what they say then.
  22. Reason

    Started my journey. Thank you.

    ~4th Month Update Currently feeling very good. Sky high libido, great energy/focus/etc., great performance at the gym, positive body composition changes. When I get a good night's sleep, I feel AMAZING. After finding out my E2 was VERY high, I started taking Anastrozole .125mg 2x week. I'm...
  23. Reason

    Started my TRT journey on June 5 2018!

    I started mine earlier this year and I've never felt better! Still tweaking things, but it changed my life. Good luck!
  24. Reason

    Lifting/lowt symptoms

    My theory is that once you start lifting you notice your symptoms more or you start relating them to low testosterone, whereas before you might chalk it up to garden variety depression. When lifting, you are in a mind state where you’re trying to improve your own body and are, therefore, more...
  25. Reason

    Help with Follow-Up Labs Cost and Alternatives

    Thank you for your reply, Dr. Saya. I used the store and added the follow up panel to my cart ($237 I believe) plus all the other tests and it came to almost $500. Unless there’s a combined panel I’m not finding on my own, I wasn’t able to find a way to lower the cost. I contacted your staff...
  26. Reason

    Help with Follow-Up Labs Cost and Alternatives

    I have my first follow-up consult with Defy and the labs they've requested are double the initial cost projection of $250, to about $500 so I'm looking for help figuring out my options. I've Kaiser in NorCal and they won't cover labs from outside network physicians. My primary didn't want to...
  27. Reason

    Types of marijuana best for stress and anxiety

    I recommend checking out Leafly. It's hit or miss, but a good starting point to look for strains that may help. I would also recommend CBD alone or CBD-dominant strains. They're hard to find and usually more expensive, but worth it. CBD has no psychoactive effects and can be taken safely for...
  28. Reason

    Recent labs: HIGH Estradiol. Causing sleep issues?

    I know you keep banging on the hypothyroidism drum but I didn’t experience many of the classic hypothyroidism symptoms pre-TRT. Hypogonadism fit better and was confirmed through blood tests. Pre-treatment my T and FT levels were the only anomalies on my labs. My E2 is almost double where it...
  29. Reason

    Recent labs: HIGH Estradiol. Causing sleep issues?

    Had my consult and got more labs back. Here's an update. Spoke with a NP who recommended: - Start .125 Anastrozole 2x week, increase to 3x week if necessary - If the AI does not ameliorate symptoms, remove HCG and re-evaluate - If symptoms subside, add HCG back slowly to find ideal dose This...
  30. Reason

    Recent labs: HIGH Estradiol. Causing sleep issues?

    @S1W: This is great perspective and I really appreciate it. Sorry you had to deal with gyno... it was awful for me and once I got it removed my life changed. Labs were drawn on trough, literally right before my next shot. I agree, I’m probably on a too high dosage, but we were shooting for...
  31. Reason

    Recent labs: HIGH Estradiol. Causing sleep issues?

    Interesting. Thanks for the info everyone. I just drew follow-up labs but the only thyroid items in the order were TSH and RT3. TSH was normal pre-treament, but I know this is incomplete info. I'll see when I get results back if they'll tell me anything and consider a full thyroid panel. Even...
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