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Currently I am waiting on insurance pre-approval to begin Telmisartan. Hopefully it will work because the Losartan @ 100mg/daily isn't doing much. One thing I am curious about is: I've read that Losartan does a bit of myostatin inhibiting - is this the case with Telmisartan (all ARBs) as well?

I’m reading that Losartan can take 3-6 weeks to reach maximum effect...how long did it take for Losartan to work on all of you? Was it gradual or did it work right away?

Thank you very much for the thoughtful reply! Like you, genetics definitely play a role for me as well; on my father's side there has been a long, long history of heart problems, strokes, high blood pressure, etc. and my BP has always ran on the high(er) side. Now I think I have compounded the...

How long did it take your actual blood pressure to start to lower? I was on Lisinopril for only a few days (it lowered my BP to 108/74 by the third day) when I learned about the SHBG raising and Free Testosterone lowering side effects and switched to Lorsartan 50mg/day. That was 6 days ago and...

Hello! Looks like I’m in need of some advice… I am not currently on TRT (tried it previously) but I know from reading on here that a lot of you are very experienced in all kinds of issues like I’m having so hope some of you can help to explain why I’m having the results I am. For reference...

@ Vince: I had blood drawn yesterday so I should hopefully have my thyroid results by the end of the week. I'm not sure if you were asking me but I used Cytomel (Cynomel) to clear my high RT3. I was over-range on my RT3 but the rest of my levels were dang near perfect and my symptoms were all...

Yeah, I could probably run another round of tests in a week or so. I was just hoping there was something else I could do.

@ Guided_By_Voices: I honestly could not say if I am a “fat burner”. Previous to my RT3 issue, I always ate more carbs and less fat in my diet and that served me fine and so that is what I have continued to do up to this point…but that doesn't mean I am right. I was also doing a bit of...

I am really hoping someone here can help guide me and I'll try to keep it brief. Background: I had an infection that lead to a dramatic increase in my RT3 so I had to clear it. Over the course of the approximate year of not knowing what my issues were I started slacking off at the gym (due to...

I'm actually talking to another doctor tomorrow. I've been to about 5-6 so far and not a one of them believe RT3 is "thing" even though I have all the hypothyroid symptoms (lethargy, weight gain, cold body temps, cold hands and feet, anxiety, etc.) so that is why I had to order T3 (Cynomel)...

Well my diet has been horrible the past few months. My blood pressure has actually gotten a little better in the past week or so but that may be due to my starting Gene's N.O. Stack (minus prescription products). I do have a family history of cardiovascular disease (one of the reasons I wanted...

Well I wasn't stopping at 25mcg (6.25mcg x 4) a day; just titrating up my dose to avoid any side effects like heart palpitations, etc. My goal was to get up to 50-75mcg and hold there for 6-8wks then taper off. Those were my plans but I just had those two questions (weight gain and tiredness)...

Below are my most recent labs.... TSH = 1.28 Range = 0.450 - 4.50 FT3 = 3.7 Range = 2.0 - 4.4 FT4 = 1.39 Range = 0.82 - 1.77 RT3 = 26.2 Range = 9.2 - 24.1 T4 = 7.8 Range = 4.5 - 12.0 I started on T3 for 8-12wks just to clear my elevated RT3 then I will taper back off. I've never used any...

So I started titrating T3 last Thursday and had a couple of questions... First, it may be a weird coincidence but I've put on like 3-5lbs since I started so I'm guessing it would have to be water weight. Is this common? Second, on a couple of days I have been extremely tired a couple hours...

I would for sure; getting all of the invidual ingredients and trying to measure them out to the suggested (in this thread) serving size is tedious compared to buying a turnkey product - that hopefully tastes better but not at the “expense” of a bunch of calories / sugar.

Thank you, Bombaac. I definitely plan on taking it slow; those side effects of too much T3 do NOT sound like anything I want to go through. I had to stop TRT because of anxiety / BP complications (probably due to my thyroid issue) so I do not want to start that all over again.

That's great to hear, Kaliman911. I have added Milk Thistle to my vitamin / supplement routine already (about 2 weeks ago) so I'm glad to know I am on the right path there. Since I am not currently using or never have used any type of Thyroid medication I'm hoping this T3 only medication clears...

Very interesting to know, Tiwas. I have read that 25mcg is a "full replacement dose" as well...so does then mean 4 does x 25mcg = 100mcg? Also, if you don't mind my asking, are you / have you been on thyroid medication previously? Or is your situation like mine? I have never been on any...

I wouldn't either but I also wouldn't dose it 100 x a day :) I was just throwing out random examples looking for advice.

Thank you very much. I'm going to go read those now.

Thank you too, HarryCat, for the reply. I did know about tracking temps and symptoms as well. So no one has any guidelines in terms of dosage to start off with, the frequency and the ultimate amount I need to titrate up to? I'm talking about amounts in “mcg”...like do I start off with 6.25 (1/4...

Thank you for the reply. I am pretty familiar with RT3, what it does and what caused (in my particular case) for my RT3 to be elevated and it has been remedied for about 6+ months but my RT3 has remained elevated. I am looking for specific info on dosing; how much, how often and for how long to...

I will be taking T3 only medication to clear my elevated RT3 and hopefully remedy my hypothyroid symptoms but I am looking for advice from those with experience. I cannot find much to reference but based on what I have found it seems like it will take 8-12 weeks to flush out the excess RT3 and I...

I actually just got off the phone with them. It looks like a possibility. They are looking over my existing blood work to see if it will suffice to get me going.

Seriously? So Defy will prescribe T3 only medication? Preferably sustained release but I'd settle for anything at this point.

Well you're right about the “most doctors” part from my experience so far. But other than that I think you're probably just not familiar with elevated RT3 (I wasn't either until I discovered it was the cause of my health issues and now have spent countless hours reading and researching over the...

So today I went to yet another doctor who tells me that RT3 means nothing and me levels are "within range". So guess I am going to have to try to do this myself so I would appreciate any guidance on how to titrate up the dosage and what my ultimate goal would be (it seems like most are able to...

FeelingLost: Thank you for the reply. It's been quite the journey :) I have wondered as well if there was something wrong with the testosterone since my levels didn't raise very much but on the other hand would I have had all the bad effects (high BP, anxiety / adrenaline, etc.) if it wasn't? So...

Thank you for the reply, Vince. Nearest I can tell it definitely uncovered a thyroid issue for me...although if had known what to look for I probably would've looked into thyroid prior to beginning TRT as the symptoms lined up. Plus, now I have blood work to reinforce those thyroid symptoms...

Hello all! Please bear with me as I lay out what has been a pretty crazy 15 months or so of my health declining. I wasn't sure which forum to post this in as it crosses over so hopefully I chose correctly. Improper root canal so infection was sealed in which caused...