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Defy has me on 126mg test / 90mg nandrolone per week. The nandrolone is to help with some chronic joint pain issues, and from what I understand 90mg to 100mg per week is a common dose for that particular use.

Also, still maybe worth talking to your doctor if everything else, especially e2, is in a good place. I may be misremembering, but I think I recall Dr. Saya saying that prolactin levels in the double digits can cause issues in some men even if technically “in range.”

Before starting caber, mine was at 26.3 (4.0-15.2). Caber starting working pretty quickly, and brought my prolactin down to around 5.0 on a dose of 0.125 twice weekly.

Have you checked your prolactin levels? I was struggling with a lack of penile sensitivity and difficulty reaching orgasm. I tried PT-141 first and couldn't handle the sides. It gave my insane erections and helped a bit with the sensitivity issues, but then I'd suffer from flu-like symptoms...

Just wanted to piggy-back on this, because it's good advice. I'm under physician-monitored TRT and after several years of treatment and my levels being dialed in, as well as learning about the kinds of necessary bloodwork and what to watch for, I feel like if I had to, I could manage my own TRT...

Thanks, Nelson. Definitely not fun, especially at 40 years old, but (for now) I trust my docs so hopefully we'll figure out a plan. Doc said if CT shows issues with the prior anterior fusion, he may want to fuse from the posterior side, maybe L4-S1. If the CT is clear at the surgical level, by...

It's also possible you have elevated prolactin. I did, and while it didn't really affect my libido, it made it damn near impossible to orgasm. A low dose of cabergoline took care of that. Probably worth getting your prolactin checked.

I have not tried naltrexone. I've read a little about it. It seems to help a fair amount of people, although some of the sides people report are concerning (anxiety/sense of doom, psychosis, etc.). It's worth discussing with my doctor though. Initially, my issues were a collapsed disc at L5-S1...

Looking at those codes, it looks like one of the pharmacies is shipping standard (S01), which is normally $12. The other code (S06) reflects express with ice packs. I'm guessing that's $40. I agree that seems pretty steep, and I guess if it has to ship that way you don't have much choice, but I...

Sorry to hear that. My first experience with OSP was pretty easy and seamless, but I suppose that doesn't mean future ones will be. Were you using them for something other than HCG?

Thanks for sharing all of this, Nelson, and as others have said, you look fantastic. I can't believe you're 63. This caught my attention. Just curious what you've used them for. I'm battling chronic pain related to some lower spinal cord and SI joint issues and did a few ketamine infusions for...

Your timing is impeccable. UPS just delivered it about an hour ago. It comes lyophilized with bac water separate and has to be reconstituted. I was surprised that the included syringes are 27g 1/2". A bit heavy and long for my taste for sub-q HCG injections, but I can use them for my shallow IM...

I've seen a number of threads about sourcing HCG now that (hopefully only temporarily) compounding pharmacies like Empower are prohibited from manufacturing it. I just wanted to share my recent experience getting it through Optum Specialty Pharmacy. I had my regular consult with Dr. Saya at...

I had the same issues with Clomid, and my estradiol went through the roof. I was very irritable and emotional on it. Not sure if that was because of the high estradiol, but I never felt good on it even though my testosterone levels skyrocketed.

How does enclomiphene monotherapy compare with clomiphene monotherapy? I was about to type up my own experience with clomiphene monotherapy when I noticed that enclomiphene was being discussed. I remember vaguely enclomiphene being discussed on here back when I was on clomiphene (2017), but my...

Just wanted to update this thread. Dr. Saya prescribed cabergoline at 0.125mg BIW (0.25mg/week), so a pretty low dose. I've been on it now for a little over three weeks, and it has definitely helped some. Sensitivity isn't quite where I'd like it, but it's noticeably improved and I now can reach...

This is pretty interesting stuff. I started a thread last week about this very issue. It turns out my prolactin is high (26.3 (range 4.0-15.2)), likely from the Lyrica I take for neuropathic pain. I see in the materials above that the suggested starting dose for cabergoline is 0.25 BIW. Dr. Saya...

I'll look into the selegiline and discuss cabergoline with Dr. Saya. Unfortunately, I can't really do anything about the medication. My spine-related nerve pain is unbearable without the Lyrica. I'm trying other treatments to help with that pain as well like ketamine infusions and steroid...

To update this thread, I had my prolactin tested on Tuesday, and the results came back today. It is definitely high at 26.3ng/mL (range of 4.0-15.2). I plan on reaching out to Defy to discuss, but does that seem high enough to cause or at least contribute to the anorgasmia issues?

Thanks. That had slipped my mind, but I remembered and reached out to Defy for the lab order. Going to get prolactin tested early next week.

Thank you. This is very helpful. I did not know Lyrica/pregabalin could significantly increase prolactin like that. Before starting TRT, Defy had me try clomid therapy and my prolactin was tested once during that phase back in 2017 (6.1 ng/mL), but hasn't been tested since. I'm not sure that's a...

I hope I'm posting this in the correct sub-forum, and I apologize for the wall of text. I'll preface this by saying that I've been a TRT patient with Defy for several years now. I've had great success and TRT has helped immensely. Historically, I've never really had any sexual performance...

I agree. I’ve tried 26g, 27g, and 28g, and prefer 27g 1/2” for shallow IM.

As others have stated, I've never seen anything longer than 1/2" for 27g or smaller. You can get a fixed needle 26g in 5/8". Easy Touch Tuberculin Safety Syringes with Fixed Needles - 100 Count &nbsp|&nbsp OTC Wholesale

Thanks for posting. I just checked the portal and mine says the same. Now I'll call Defy for a copy.

Sure thing. I just checked the LabCorp patient portal and there was no sign of them, so I’m assuming it will be sometime next week at best.

Bizarre that they only have ONE machine for that.

I looked back at my labs over the past two years, and the longest delay was like 6 days for me, and that was with a Friday blood draw. Most are back in 4. I have no idea why mine seem to come back so quickly most of the time when others regularly see 7-10 days.

Just an FYI that apparently LabCorp’s only machine for testing sensitive estradiol broke down, causing a backup on processing lab results. My most recent blood draw for TRT labs was September 24 and still no results. I called Defy yesterday to see if they had received anything, and was informed...

My wife's labs are attached. For reference, she was follicular phase for everything. I'm seeing extremely low testosterone levels, normal LH and FSH, in range but lowish estradiol, in range but low progesterone, and everything else seems fine other than just above range LDL cholesterol...

I'm a fairly long-standing Defy patient, and my wife now is interested in getting all her levels checked. Rather than going through the whole Defy initial consult process without having any idea of where her levels are, I purchased the Hormone & Wellness Panel for Women from DiscountedLabs as a...