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    Applying Critical Thinking to Longevity Research: Video from Chris Masterjohn

    The linked video has IMO a lot of great points that everyone who follows the developments in this area should be aware of. It's very relevant for the IMO over-rated concept of calorie restriction and the anti-Growth Hormone arguments, and lots of other topics as well:
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    Salt, Blood Pressure, and Libido: Highlights from the book The Salt Fix

    I just finished reading the book The Salt Fix, and it addresses many topics which have come up in various threads here so I am posting some highlights, along with a few other items not covered in the book. The book has been out about ten years and I have heard many podcasts with the author, but...
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    20 Heart-Healthy Actions With Better Risk/Reward Than Statins

    Here at Excelmale there are frequent posts discussing the pros and cons of statins, and one in particular several weeks ago where a position paper was cited where the assumption was that statins are not only a viable option but should be the first line of defense against heart disease. As I have...
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    PT-141 officially FDA approved (for women)

    FDA approves new treatment for hypoactive sexual desire disorder in premenopausal women PT-141 AKA Bremelanotide AKA Vyleesi approved. This should open up a whole new focus on the melanocortin system and allow for crowdsourcing the best dosing/timing. It seems something good is happening in...
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    Fixes for Joint Issues: A list of Some Basics

    Every few months or so, a post seems to come along saying something along the lines of “should I do PRP or Stem Cells or Nandrolone or anti-inflammatory injections or [insert something exotic here] for joint issues”. While all of these and others likely have their place, they are often either...
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    High-Dose Niacin: A Cautionary Tale

    High-dose Niacin was generally considered very beneficial before about 2010 but then fell into a bit of disfavor without much credible change in the science. I have been watching the evidence for a long time and it seems incomplete but generally positive. I have tried niacin on and off without...
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