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  1. G

    Updated Labs - Help Please

    I've had issues with unexplainably low E2 as well but it seemed to resolve after a while and rose to more normal levels (a while being a year or so). A lot of things I wouldn't have expected can interfere with the aromatase enzyme, such as zinc, so you might want to review you supplements and...
  2. G

    New to TRT. Received first labs. Concerned and need help.

    How about starting a thread dedicated to whatever it is you're arguing about and leave this and other threads to the specifics of the OP's topic. This has become like bar fight that spills out of one bar and goes up and down the street into other bars. My contribution to that thread would be...
  3. G

    New to TRT. Received first labs. Concerned and need help.

    It's way more nuanced. Some compounds, specifically Anadrol, are well-known to make people look red. There are plenty of people who likely have high-blood pressure. The "dry" look of thin subQ fat layer can make some people look red. Boldenone can raise HCT. and increase vascularity. But the...
  4. G

    Can blood work be incorrect?? Really confused

    There are other options. What issues are you looking for the TRT to resolve?
  5. G

    Can blood work be incorrect?? Really confused

    For results that extreme, my approach is to immediately test again if possible and assuming no symptoms. I had elevated HCT for a while and I can say that it is essential that you be fully hydrated to get an accurate test. I would schedule your tests late morning and drink at least half a gallon...
  6. G

    Advice and next steps. 38 years old with 305 total t

    First, IMO, there are many things you need to explore before going on external T. It is nowhere near as simple as many make it out to be. Since your sexual function is still fairly good, I would be doubly cautious because, as many men have reported, TRT can mess that up and not have it resolve...
  7. G

    New to TRT. Received first labs. Concerned and need help.

    Sparky's comments remind me that intestinal permeability (leaky gut) could be at play here too. There are tests for that (LPS?) but it seems better to just follow a protocol that would cure/prevent the leaky gut, such as Dr. Gundry's Gut Check protocol.
  8. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    In general, poor health is accompanied by a decline in Nitric Oxide production. The Viagra class of drugs blocks an enzyme that breaks down nitric oxide so it indirectly increases Nitric Oxide if someone is producing good amounts in the first place. Dr. Kendrick points out that these drugs far...
  9. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I do too many things to list but I made a very quick starter list below. While the book has as section on specific recommendations which, for example, caused me to start niacin again and measure LP(a) and homocysteine, the bigger impact for me was that by better understanding mechanisms of harm...
  10. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Taking magnesium, K2 and vitamins A, K and E (full spectrum) may help absorption, but that sounds strange. Some infections "hijack" vitamin D, but I really just don't know. You might look into Chris Masterjohn's writing on the topic particularly around interaction with the parathyroid hormone.
  11. G

    New to TRT. Received first labs. Concerned and need help.

    Some comments in no particular order. - Your Vitamin D reminds me that there are apparently some infections that use the Vitamin D receptor as an entryway into cells, and for those infections Vitamin D can make actually make things worse. Dr. Michael Ruscio (who you should also look into) did a...
  12. G

    New to TRT. Received first labs. Concerned and need help.

    I agree with everything Funk said. Regarding mold, which I forgot to mention. I think what you want is a test that determines if you have been exposed and have some sort of damage from it. You could have been exposed elsewhere. A doc who specializes in that type of thing would be good to...
  13. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    I really admire the creativity here, but I'm puzzled by using crushed tadalafil. Since you're basically (potentially, dependent on absorption) injecting the fillerr and binders, I would think there could be a risk there if those are things that are not absorbed in the digestive tract when taken...
  14. G

    New to TRT. Received first labs. Concerned and need help.

    Your symptoms scream chronic fatigue syndrome and hopefully someone here with experience on that topic will chime in (possibly @FunkOdyssey ?) which if IIRC can be from chronic infections and/or micronutrient deficiencies. From what I've heard, mainstream doctors are fairly awful at resolving...
  15. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    This is another reason I am not a fan of ChatGPT. First, the point of the book is to propose a model of heart disease which actually fits the data we have about CVD. While there are a number of recommendations in the book. the bigger picture is that there are literally hundreds of risk...
  16. G

    Factors Involved in Immune Resilience and Longevity

    It's puzzling that, at least based on the notes, he doesn't say anything about strengthening the innate immune system, specifically with Vitamins and minerals like D, C, and Zinc. Supplements like Beta Glucans apparently help as well.
  17. G

    Alcohol Consumption and TRT/HCG

    DHM (dihydromyricetin) is an amazing compound and among other things aids in metabolizing alcohol.
  18. G

    Alcohol Consumption and TRT/HCG

    While I would never recommend drinking in large amounts, or in any amount for someone who does not have a good relationship with alcohol, there are three big problems with the anti-alcohol push. First, the observational studies have grouped heavy drinkers in with light social drinkers. I have...
  19. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    This would imply that the DHT Enanthate is at risk as well if there is no longer any source for raws.
  20. G

    TRT Dose question

    I will be curious to hear if you are able to maintain healthy e2 level with that protocol. Also, I'm glad to see TNE becoming the standard term for straight testosterone again. Alternate terms like native T just create confusion IMO.
  21. G

    No.1 Protein Scientist: Are you eating enough?

    I didn't watch the video, but my understanding from other sources is that while technically plant protein can, in the right combination, approach animal sources, in the real world you would have to eat so much of it that it is both impractical, and what plant protein comes bundled with could be...
  22. G

    BPC-157 injection site importance?

    Peptide sciences is the trusted go-to, but I have had very good results with the patches from Phase4 (formerly Ageforce) and I find them very easy to put where ever I'm having an issue.
  23. G

    Help identifying this arm injury??

    That sounds somewhat like what I had which I think was Cubital Tunnel Syndrome. In my case it was the nerve that goes past the funny bone in your elbow becoming irritated and out of place. As with all joint injuries, use very light weights to get blood flow through the area at least once a day...
  24. G

    Testosterone clinics - Do they know what they are doing?

    This the key IMO. There is no substitute for self-education, and as I've pointed out many times, the body is a highly interconnected set of systems, and a lot of urologists and clinics are likely jumping straight to hormone-centric treatments when the underlying issue is something else like...
  25. G

    NUTRITION MARKERS TO TARGET ON TRT AND WHILE AGING.

    It's worth noting that the body's need for Vitamin C rises massively when fighting an infection since Vitamin C is kind of like the body's version of "ammunition" for the immune system "gun". Also, it's almost impossible for most people to maintain D levels above 50 (where the evidence seems to...
  26. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I strongly recommend the book "The Clot Thickens" for all things cardiovascular. Low LDL is not necessarily risk reducing. What you want is low triglycerides, low fasting insulin, sunlight, nitric oxide, good vitamin C and D levels and an avoidance of blood sugar spikes. That's a basic starter...
  27. G

    First set of Follow Up Labs since Starting TRT. Looking for Feedback

    If you have an anti-viral protocol it sounds like now would be a good time to take it. If not, upping your Vitamin C dose to around 5grams and also ideally adding in liposomal C is a startig place to consider that has worked well for me. There are lots of other things like quercetin and beta...
  28. G

    Testosterone clinics - Do they know what they are doing?

    If the reports we've seen here are an accurate sample, "board certified urologists" are no better than clinics. Different perhaps but not better.
  29. G

    TRT+ other medications

    For someone who wanted to try the progression I described earlier in this thread, here’s an example of what it would look like using OP’s weights: A basic core progression could be: 325lbs 4 sets of 2 reps, adding one set each week for eight weeks until 12 sets of two reps is reached. Finish...
  30. G

    TRT+ other medications

    I trained in a loosely similar way for several decades and after I got past about 70% of my likely potential (before which almost anything works) I ran into three big problems. The first is that I simply ran into a permanent plateau where I couldn't add any more weight or reps. The second is...
  31. G

    TRT+ other medications

    Regarding Primobolin, it can have the affect of creating low estrogen symptoms and destroying libido. If you were going to try anything to add to TRT, I would vote for a LOW dose of oxandrolone, specifically no more than 10mg pre-workout, no more that 4 times per week. I'm increasingly of the...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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