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  1. S

    Creatinine & eGFR

    As I feared would happen, my creatinine and eGFR levels are getting worse while on even low doses of testosterone. 02/12/2021 pre-TRT Creatinine 1.10 ML/MIN/1.73, 0.80-1.40 eGFR African American 93 ML/MIN/1.73, >60 eGFR non-African Amer 81 ML/MIN/1.73, >60 11/06/2021 pre-TRT Creatinine 1.36...
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    Worsening Symptoms, "Dead Penis"

    Instead of taking Defy's dosing advice, I tried going "low and slow" for six weeks, but my libido and sensitivity completely dried up after a couple of weeks. Defy had recommended 100 mg T cypionate/week, divided into three doses, but I went with 10 mg/daily. They have also recently added hCG...
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    How To Use Defy/Empower Nasal Gel Pen

    I received my first nasal gel pen in the mail from Defy today, but it came with no instructions on how to actually use the pen. The only moving part is the rotating clicker at the bottom. I rotated it fully (several clicks), but nothing came out the dispenser. There is no pump or any other...
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    Acceptable Air Bubble?

    No matter how I try, I am always left with a tiny air bubble. I ever so slightly overfill beyond my intended dose to make up for it. Should I be aiming to have zero air bubble in the syringe? I've included a pic of the air bubble in my 10mg daily shot.
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    Should I Be Worried About My Blood Pressure On TRT?

    I'm hypertensive with blood pressure usually measuring about 130/90, but my PCP hasn't put me on any medication. I started TRT a week ago with low dosing. Wondering how cautiously I should proceed here.
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    When To Test For Peak Or Trough

    How many hours after I inject cypionate would I test the highest? How many hours before the injection would I test the lowest? Is it as simple as just before the next injection? I am on an EOD schedule.
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    Starting HRT, Mainly for Libido

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    New Guy Looking For His Libido

    Hi, I joined here because I found so much info here on how DHT helps libido. I was on injections. I gained 20 lbs of muscle on low dose cyp, but no libido. Just added transdermal to scrotum to up DHT as of yesterday and waiting for results. Already having sex dreams and night wood, but no...
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