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Thanks for this thorough article on RA. (Was diagnosed myself about 20 years ago) For anyone who has RA, important fact, 65% of males with RA have low T

Your answer is usually accurate. I use T Cyp, 200mg/ml, so the math would be (total 10ml vial) 2000 mg=10 ml so 200mg = 1 ml and 100 mg = 0.5 ml (my dose is 8mg qd (daily)/ I dose every other day (QOD) at 16mg = 0.08 ml The...

One suggestion I would make is to find a person who is knowledgeable on marijuana and which types suit the purpose you need. If sleep is (close to) 100% of your rationale for its use then there are a huge number of options to choose from for whichever issue you hope the MJ will solve. Looking...

When I was working, I told my older patients who had that complaint, about night time urinating, a plan for helping. I suggested when they wake up they drink from their largest glass, after dinner they should shift to the smallest glass, if they awoke in the night and needed to drink, I a shot...

I can answer this question. Have severe RA (Rheumatoid Arthritis) and take a biologic med (Humira) and a chemo drug (Methotrexate) for meds for the RA, was diagnosed 20 years ago. I awoke multiple times at night in the past, mostly from turning, and the pain in my joints would wake me up. I got...

As my coffee mug say's, I am not retired, I am a professional grampy. So, I was planning on visiting the grandson for a couple weeks, I had time in the AM before leaving to get labs, and I woke up at 1am,applied the T cream and got tested at 0830. ( he lives in a non testing state) I have a...

I did get one free E2 test a few years ago, because of my low SHBG, the results were WNL, but there are no real optimal levels listed anywhere, so I don't know what we can do with the actual results. I lost my account last week, and I got a new account, thought I would move the question over...

I have to believe that the <2 E2 was a lab error, it came up at the next lab test with very little changes. I did dilute my scrotal cream from 50mg/ml to 25mg/ml , that brought my FR/TT both within range . (My MD writes an Rx for 200mg cream, then I dilute it 400%, do this mostly for cost...

For those who have never heard about LDN (low dose naltrexone) it is an anti opiod drug that taken at lose doses has a positive effect on the immune system. It helps the immune system by temporarily (aprox 2 hours, during the night) decreasing the amount of dopamine receptors, your body reacts...

Sad the researchers had to define male and female, (to protect them from the trans community) but, that's the way things are heading (for now) in the PC/Woke world.

Thanks for your response, do you think increasing DHT (R/T Test Cream to scrotum) was the only factor at work? Or did you have any other issues that changed when your E2 dropped? I am unsure at what is in play here, my issues are the low SHBG, and the cream raising my TT and DHT. E2 has to have...

Agree, I would be suspect of the result, but, I had two labs with those low E2 levels. My first was 5, and I wasn't sure about accuracy, and I didn't feel different, so waited. I retested a month later and I believe it was accurate when it came out <2, after no protocol changes, and two low E2's...

My SHBG has run in the 12-15 range with pretty much any TRT changes I have made. My protocol last month was T Cyp (SQ) 24mg x3/wk, HCG 200 iu 3x wk, DHEA 25 mg 3 x wk, Pregnenolone 50mg 3 x wk, and T Cream to scrotum each night, a very small dose. Seemed to work, and a set of labs found DHT was...

Establishing a patient portal account helps with getting quick lab results for either Lab Corp or Quest. Better for you to see the actual results, not just hear the doctor proclaim the usual (BS) "your fine, everything is within normal limits". Accepting this comment is a mistake, we always...

Have you had your Thyroid tests checked recently? Hypothyroidism and high total cholesterol are related. I just wrote this exact comment a week or two ago, that pre 1960, cholesterol testing was done, but not as a cardiac measure, but to discover hypothyroidism.

I have two comments, the first is personal, my total cholesterol was aprox 220, I started Low Flush Niacin, my total dropped to 185. I made no other changes for a few months when I was trying the Niacin. The suggestion to get your thyroid optimized is sensible. Prior to 1960, total cholesterol...

I feel like the TRT was working well, but....the joint pain confused me, I thought it was the RA, but then when I got my E2 test results, I realized the ankle pain was related to the low E2. I just need to adjust my TRT protocol slightly, so my e2 goes back to the usual 25 (or so). I will more...

You read my FT wrong, " my TT was 491 and FT is 118 ( 35.0-155.0 pg/mL ) this is the lowest FT I have gotten " . Lowest level of FT in years since I started TRT, you were close on Albumin, its 4.5 (3.6 - 5.1) . Estimates may work for some, but I have other underlying health issues, and have...

Thanks for your thoughts. I wish I had my SHBG ever get as high as 25, unfortunately, it is always around 12-15. (sometimes slightly off that, but not by much). My FT is all I am watching now, until I cut my T cyp even more (I was taking 20mg 3 x wk, with a TT between 850- 1100, and a very high...

I am seeing my rheumatologist in a week, (have RA) and got a few labs to bring in, also wanted to see how my TT and FT levels were looking. I have very low SHBG (10-15 usually) and so my FT is always high. My regimen has changed a bit over the years, currently my goal is to decrease my FT, it is...

Because of my auto immune disease, inflammation is the critical factor in everything I feel. As I understand it, Omega 3's are anti inflammatory, and Omega 6's are pro inflammatory. Nuts and seeds are healthy, in very small portions, but for those of us, (you included) we need to limit our...

Sorry to hear about all these health issues you are facing, it sounds like you need more calories, but your current diet limits this. Have you considered a Paleo diet? I have an autoimmune disease, and started my trip towards healthier eating by going Paleo for a few years, then slowly...

Would you mind sharing the ratio results? I think this is a great opportunity to pass along info about the historic ratio, 10,000 years ago it was close to 1-1, today as high as 1 - 50. When I did mine it was 1-3, I was thrilled, but never met anyone else who has had the test done, or found if...

For those so inclined, there is another choice. I use a locally produced (OK, I buy my MJ from a guy at my gym) CBD stronger tincture, it has less THC than the OP wrote about. I use aprox 2/3 rd of a dropper an hour before bed, and it helps me sleep. It also has helped me keep my CRP below 1.0...

When you say you get your levels checked, do you mean the omega 3 to 6 ratio? I did that test a decade ago after a couple of Paleo years.

As opposed to abortions, which are called essential and even described as "Life affirming". Nothing like bringing politics into medicine and disease.

Can i insert another variable, which is popular at this time? How does raising DHT with scrotal T cream effect E2? As I understood it, higher DHT decrease aromitization, and thus possibly lower E2 levels for those with low SHBG. (I have only been over 15 once or twice in the past decade)

Is your back pain localized? Right above your belt line? I had good luck with prescribing (Fentanyl/narcotic) pain patches, if when I asked the patient, where is the pain,if they pointed with one finger, I tried a patch, if they waved a hand, they never really worked.

I would think any mood effect would be related to testosterone.

You are correct, wouldn't work, although Naltrexone is an immune modulator or booster, at the full dose of 50mg you would get terribly sick if you took the pain meds. Myself, i hated doing it, but if I have pain , lasting more than a few days (this was in the past) I have used Prednisone to...

Never, I try and never use any NSAIDS, (and never an Opiod) I would guess I take less than a half dozen Tylenol a year. You are correct, Naltrexone is an anti opiod drug at full strength (50mg) my son has very high thyroid antibodies (hashimotos) and is now taking 3 mg every night. I take 4mg...