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  1. H

    Telmisartan for high BP - a caution

    Four years ago I started taking Telmisartan 40mg for high blood pressure. Everything I read said it had other benefits... reduces weight gain increases total energy expenditure increases expression of key mitochondrial enzymes in skeletal muscle multiple mechanisms to protect...
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    Fasting may not be so safe?

    Yes eat as much as you can!
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    Fasting may not be so safe?

    Article was assembled based on many reports funded by the Academt of Nutrition and Dietetics. "The association is funded by a number of food multinationals, pharmaceutical companies, and food industry lobbying groups, such as the National Confectioners Association." So the food industry doesn't...
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    What are the best vitamin/supplements for Liver health?

    Sorry that was sent before I finished. Milk thistle brings my ALT/AST down to 15/15.
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    Relationship Between Higher PSA and Higher SHBG

    " reasons why my SHBG would be on the higher end" My notes tell me SHBG is driven up by cortisol, probably where I'd start.
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    for those that suffer from occasional prostatitis.

    It's oregano oil that comes in a small bottle, Whole Foods or Amazon have it. Just 3 or 4 drops daily on some food to absorb (some of) the intense taste! I believe it's a strong antibiotic, antiviral and anti-inflammatory. I wouldn't take it for more than 2 - 3 weeks.
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    Statin use and TRT

    Your liver is manufacturing that cholesterol within a feedback circuit. If you are going to interfere with that mechanism by suppressing the manufacture of cholesterol in your liver then maybe you first need to consider the downstream impact. Cholesterol is the precursor of the five major...
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    MTHFR gene mutation

    But you only need it once in your life! :)
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    MTHFR gene mutation

    Hi Vince, Up to 50% of the population have one of the, I believe, three types of MTHFR mutation. It causes systemic inflammation by interfering with methyl group processing in the body. It impacts homocysteine metabolism (it did for me). I just read Mayo Clinic notes on the mutation test...
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    High levels of two hormones in the blood raise prostate cancer risk

    Absolutely, the most likely scenario is prostatitis, an often symptomless bacterial infection of the prostate. You will also find many threads on this site discussing sex, bike riding etc as possibly the cause. Inflammation can also occur for known and unknown reasons, so there's way more...
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    Heart Palpitations on TRT? The cause?

    Blinky, the American Journal of Emergency Medicine says "Intravenous magnesium has been suggested as a treatment for certain emergency conditions for more than 60 years. It is currently proposed to be beneficial in treating asthma, preeclampsia, eclampsia, myocardial infarction, and cardiac...
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    High levels of two hormones in the blood raise prostate cancer risk

    It must be really annoying for the men with low levels of these hormones who got PC during this study. It's a bit like all the people who die of heart attack and stroke and have low cholesterol.....
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    Do you bring your supps on vacation?

    I just take cialis with me. I leave the supps in the belief that I'll do fine for a week or two without them, plus the tiny hormetic stress response of stopping them might be good for me.
  14. H

    PSA at 5.3

    Here is another FWIW. In 2016 I had a surprise test result... PSA 5.6 No symptoms. Off I went to a urologist. DRE normal. Urinalysis said no infection. I got the statutory course of antibiotics from the urologist and... PSA went down over next three months 2.2, 2.1 and finally 1.3. I think...
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    Kidneys and Citrulline

    Here's some fun facts to be aware of when testing Creatinine level. My thoughts are that since there are pharmaceuticals that raise Creatinine I wonder how many other compounds out there do the same thing. Know the Medications That Spuriously Elevate the Serum Creatinine Level. In a number of...
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    Kidneys and Citrulline

    Vince, to avoid worrying about kidneys get a cystatin-C blood test done, Nelson's lab has one.
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    for those that suffer from occasional prostatitis.

    I believe oregano oil helped with finally "curing" my chronic prostatitis about 18 months ago as the pain went away a few days after I started the oil. But that's just me, n=1.
  18. H

    TRT without the use of Aromatase Inhibitors

    Well said. When people have the energy and courage to put themselves forward as advocates for men's health we should not disparage. We might differ on opinion but aren't we all on the same side?
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    New Research Confirms We Got Cholesterol All Wrong

    I think the headline holds a lot of truth. If you don't have existing heart disease the benefit of statins is miniscule. The trial outcomes on average show about a hundred healthy people need to take statins for years to prevent one heart attack. Coupled with that is the risk of the statins...
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    Photodynamic Therapy...PDT...pre-skin cancer

    Yes I had it end of last year. It's a pretty easy procedure with little impact other than a red face and peeling for a day or two. Does it work? Who knows. Is my skin any different looking? No. What's the impact of creating free radicals on a large scale in your face? Um probably not good but...
  21. H

    Testosterone to estradiol ratio reflects systemic and plaque inflammation

    I thought I'd look for something that described the best ratio and found this paper which looks at things from the other end. Elevated T/E2 Ratio Is Associated with an Increased Risk of Cerebrovascular Disease in Elderly Men http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061598
  22. H

    Psa

    Infection likely caused by sex. And its not necessarily "bad" bacteria. Can be your partner's "good" bacteria that just irritates the prostate (so my urologist says).
  23. H

    Psa

    Don't assume that. In 2016 I had a psa of 5.6 with zero symptoms. In actual fact it was only that I was interested in TRT that I has a psa done otherwise I would never have known it was that high. It dropped to 2.1 after 10 days of antibiotics. Currently its about 1.4
  24. H

    Slightly elevated creatinine

    I am starting to believe creatinine is a poor first choice for measuring renal function if you work out and drink protein shakes. My creatinine was 1.2 in 2002 and 1.2 in 2017 yet my PCP said that means I am virtually stage 2 kidney disease. What my PCP doesn't see is that my creatinine drops...
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    Ask The Urologist Anything (Dr Michael Rotman)

    If you take a look at the following thread https://www.excelmale.com/forum/showthread.php?5847-Hi-everyone-new-member you will see a discussion where two of us share our bad experiences with Clomid. For myself I got excruciating pains in my left testicle that left me breathless and very...
  26. H

    Prostate infection

    For me it has been a drag. 56 day course of antibiotics cleared it at start of year. Came back recently but almost gone now. To your first question, Gardnerella Vaginitis can cause chronic prostatitis and to address that requires a concerted effort.
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    Any guys here with high SHBG?

    In my notes I have: Keep SHBG in check with Chrysin, Quercetin (inhibit aromatase), Nettle root, Fishoil, protein Combining nettle root with Pygeum results in a stronger synergistic inhibition of SHBG binding. Nettle prevents SHBG binding to cell membrane and therefore reduces hormone related...
  28. H

    AST and ALT Elevated Since Starting TRT - Is This Unusual?

    Try a milk thistle supplement. Dropped my AST/ALT from 25/38 to 15/15 gradually over about a year (age 57, weights 3x a week). It MAY detox the liver and MAY help it regenerate!
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    Creatinine lab result high!

    No creatine. Good hydration. Your thread has some comments on Cystatin-C that I think are very applicable to those of us working out a lot.
  30. H

    Creatinine lab result high!

    Here is a dialog I had three weeks ago with my PCP (not my Defy doc!). Doctor: "Your creatinine level is 1.2, that is high." Me: "I track my labs and my creatinine went from 1.09 to 1.14 to 1.16 to 1.06 during 2016." Doctor: "You said you eat a lot of protein. That can damage your kidneys...
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