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I used to get it from Empower but we know the FDA clamped down on that. I've been getting Pregnyl now through my pharmacy and it went from $120 for a 6 week supply to nearly $200.

Same with me, I have 12.5mg at home because I was going to do a re-start to get my wife pregnant but she ended up getting pregnant anyways on TRT+HCG. I've been curious to see what taking 12.5mg of Clomid on top of my TRT regiment would be.

I am a 40M who has been on TRT for about five years. My fiance is 29 and wants to have children. I decided to get a SA done to check on my swimmers. My current protocol is 120mg of Test Cypionate/week and 1000IU of HCG/week. Motility: 16 (>=32%) pH Semen: 8.5 (7.2-8) Sperm count: 3.4 (>=15.0...

Hey guys, I am a senior graduate student for my nurse practitioner, and I am doing my DNP project on improving TRT. For my literature review section, I wondered if you guys came across any studies showing knowledge gaps with providers and patients to TRT, as we know many TRT horror stories...

His sensitive E2 was low at 3.4 It was his total estrogens that were 20k. I thought Tren doesn't aromatize that much other than through prolactin pathways but its pretty dry, don't really see it causing E2 problems.

What they didn't mention is a process called neurogenesis, your neurons grow back, this is observable and repeatable. In Japan there was a study using Ashwaghanda which showed it helped with neurogenesis.

Good Lord people are still perpetuating this? Look, I have NEVER seen a permanent crash of hormones in practice, the only anecdotal accounts I've ever seen are a few from testosterone forums, there is nothing in the medical literature because we don't observe it as part of the scientific method...

Greetings, I have a TRT patient at my clinic and the fellow providers nor myself can figure this out. I have a patient who had a total Estrogen level of 20,240, with a TT of 420 and FT of 12. I had the other provider to run sensitive estradiol on him and he is pitifully low at 3.4, I had them...

Yep, individual genetics will dictate quite a bit. I've seen patients in their mid 30's who were candidates for pacemakers who had prior anabolic use, and I've seen guys who have blasted tons of gear that don't have any cardiovascular issues. Individual genetics, lifestyle and supplementation...

Yeah , there isn't a whole lot of data out there with guys on TRT with high total/free testosterone and elevated estrogen. I have taken up to 600mg of Sustanon and I didn't use an AI, I felt fine. We just don't know much due to lack of studies. As long as you feel fine and your lab values aren't...

No, we treat many patients who have had cardiovascular events at the VA, including being on blood thinners. You would need more frequent laboratory value monitoring, however.

It depends on how you feel and what your other labs look like, such as lipids, hA1C, etc. If your estrogen is elevated, I would imagine we would be seeing it have an effect on some lab values.

Elevated estrogen levels prevalence of T2DM, especially in aging patients despite testosterone levels. Circulating Estrone Levels Are Associated Prospectively With Diabetes Risk in Men of the Framingham Heart Study

Its really up to how you feel and what the labs are telling you. Some men will aromatize more than others, particularly obese men. AI's should be used if there are overtly high E2 symptoms in conjunction with grossly elevated E2 numbers. Elevated estrogen is harmful to men and women, but the...

Joint cracking is a normal physiological finding that happens to most people, and also has a psychosomatic component. The more you dwell on it, the more you are aware of it occurring.

You know I was wondering this, taking HCG myself, if the compounded stuff was as good as pregnyl and I don't think it is. My testicles also don't seem as plump on 1000 IU a week. I think I'm going to go to the pharmacy and get Pregnyl next refill and stop messing around with the compounded...

Erections and libido rely on many different variables besides androgens. You can have low T and still have great libido/erections, you can have high T and have low libido and poor erections.

It certainly is interesting and I attribute methylation to most peoples mystery issues with well being. For me, I am slow COMT and slow MAO, I've had issues with anxiety and worry, but never depression. My highs are also very high. It is VERY complicated and you're right, most allopathic doctors...

I am just curious how some docs get away with prescribing it. I am somewhat interested in a low-dose Deca, but the LVH has me spooked a bit and it is also very suppressive to HPTA axis and remains in your system for a long time. If you have to get off TRT, that Deca is only going to prolong your...

I believe TRT increases COMT which will make you burn through your neurotransmitters quicker. If you are a fast COMT, you are going to further burn through your dopamine and serotonin. I am a slow COMT, so I tend to hold on to serotonin and dopamine, so I would hypothesize TRT would work better...

Othello syndrome? Lecithin? this sounds more like a hypochondriac than anything else.

Make sure you are supplementing with Vitamin D3 as well as probiotics.

I took accutane when I was 16 for about 4-6 months. I experienced zero issues other than dry face and lips. My libido was absolutely phenomenal and so was my mood. No negative effects during or after accutane. I do not believe I needed to be on the drug as my acne was only moderate, but its only...

I've seen higher doses of Testosterone and anabolic steroids do stuff like this, but not therapeutic levels of testosterone.

I am not necessarily a fan of medications that suppress hormones but if you're a guy who needs to manage high estrogen levels then you should start low and go slow with Adex. I think comparing to "poison" is a bit hyperbole, and it's only bad when you crush your estrogen with it. I've crushed my...

He's ignorant if he believes T use will shrink your penis. He is correct that drugs have been used for thousands of years in some form or another, nothing new under the sun.

Anavar, winstrol etc all lower SHBG. There are some studies on PubMed showing the lowering of SHBG after exogenous testosterone administration if you browse around.

I know Dr. Crisler would do this for high SHBG guys. Think about bodybuilders using large amounts of anabolics, they all have very low SHBG because they are using large doses of anabolics which will drive down SHBG.

Don't you mean for low-SHBG? Generally if SHBG is high, you give a larger dose which lowers SHBG. You lower the dose and increase injection frequency with low SHBG guys.

Finasteride is the standard protocol for guys with BPH, there are a lot of medications I don't like, but if I educate a patient on the risks and they still want the drug, its not my place to talk them out of it, I am a strong proponent for medical autonomy.

"could they be permanent"....this is something in research called "fuzzy words." There is just not enough data to conclude this medication causes permanent changes in the human body, If there is, someone needs to show the exact mechanism how this happens, no speculation please, there is plenty...