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  1. D

    Requesting advice from Lab work

    This is my most resent lab. Still trying to hit the mark, but not quite there. I'm currently injecting .10 daily, due to low SHBG. I use .125 mg arimidex twice weekly, DHEA nightly and 250 IU's HCG twice weekly. I still suffer from low libido, weak ejaculation. Am I missing something? Any advice...
  2. D

    Having problems with HRT

    I have been on HRT for at least 18 years and have never got it right. Recently joined Defy hoping to get things straightened out. I'm a low SHBG guy and currently use 1 click of the 200ml cream in the AM and .10 subQ cyp daily. I also use 500 IU's of HCG twice weekly. It just doesn't seem to...
  3. D

    SHGB and Estrogen levels

    I’ve read many posts about how your Estrogen levels should mirror your shgb levels. What is a guy to do if his shgb levels are low? My shgb is at 12.....so what should I be seeking for E2 levels? Thanks
  4. D

    Requesting advice on problems in lab work

    I'm 55 years old and have been on many different methods of delivery since 38 years old. I have low SHGB and most primary care doctors don't have a clue about it. I even traveled many years ago to visit Dr. Crisler and back in those days he didn't have a clue about low SHGB. Looks like things...
  5. D

    Problems with long term HRT

    I'm 55 years old and have been on some type of HRT since I was 38. I started on androgel....worked great for about six months and my body quit absorbing. Since then I've tried about every method of testosterone delivery. I currently inject .8 ml weekly (enanthate). My levels seem to be fine from...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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