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    Can estrogen crash cause desensitization/knock out of the estrogen receptor - lets discuss!

    Since the posts on this matter are quite scattered, I decided to start a new thread. Im hoping that this one could be a hub for all kinds of discussion on this topic. If I have understood correctly the hypothesis on this is that a prolonged deprivation of ones estrogen - by using an AI - may...
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    Did estrogen crash cause me permanent symptoms of low dopamine?

    Long story short: Last fall I had my first "proper" estrogen crash with arimidex. The following months were a struggle for me when I tried to re-adjust my adex dose. Now I have to state that before that I had period of months were arimidex seemed to work just fine and I felt good. I did lose...
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    Why some men are high aromatizers - looking past the most common factors!

    Reduce your body fat, keep your diet clean and don't drink too much beer. If all those are in order you should not have problems with high estrogen. This is the reasoning we all have heard. I saw an internist a few weeks ago who said that by looking at my body type, there's no possibility for me...
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    Estrogen crash causing permanent apathy/lethargy - by destroying your dopamine neurons?

    Ive been on trt for 2 years now and had a estrogen crash this fall. From that point on I've been trying to redial my Ai protocol, and at the moment, im at a point where i've decided to ditch my arimidex completely. One of the thing that is worrying me is the fact that I cant seem to shake of...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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