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Men with Klinefelter's syndrome usually start testosterone replacement therapy (TRT) in early adolescence and take it life long. Likelihood of DVT-PE in Klinefelter's is 20 times that of the normal population, or about 1 in 50 men. We have new data that most men with Klinefelter's who develop...

We have published two new original data manuscripts which focus on deep venous thrombosis-pulmonary emboli-osteonecrosis which occur when testosterone is given to men or women with previously undiagnosed thrombophilia. We have provided new data which shows that when testosterone is continued in...