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Pregnenolone is weird, the most inconsistent supplement ever, you may be celebrating it but soon find it messing you up. The dosages are controversial, some talk in hundreds of milligrams per day, and others say 5-10mg, if i recall correctly Dave Lee recommends these low end doses. For me...

Have you stayed on preg and on that dose?

Yes i sure do, i just don't get why you would require more hcg without testosterone to get the same ITT. Is the exogenous testosterone helping the ITT in some way?

Thanks, it's funny how different people are, uHCG always resulted in early finish for me, especially anything above 250iu eod. For some reason rHCG(ovidrel) seems to not have this effect.

So you are saying that even if 500iu eod results in over baseline ITT, it is still not good enough for monotherapy, even when there is no exogenous t suppressing the testes. The studies you listed do not have a lower dose for comparison, it's always those huge amounts every time, i'm not buying...

Melatonin is not actually prescription only outside the US.

How much hcg were you on?

Yes we have, my point was why would a man using HCG be using those huge doses that are also found in most studies, there is plenty of anecdotal evidence on excelmale on the dreaded leydig cell desensitization, not to mention excess e2 etc. I dont see how the HCG dose should be different when not...

the dosing is always huge in the studies, according to this known study, there is no point in dosing over 250iu eod, especially if used as add on with testosterone. https://pubmed.ncbi.nlm.nih.gov/15713727/

Great work once again, wondering about the hcg dosages, i guess since most studies are for fertility, running huge amounts of hcg is not going to burn out the nuts in a matter of months, but if running rhcg on a continuous protocol with or without exogenous t, what would be a sensible dose...

i think youre doing too much hcg, 75 fsh i think is usually taken 3xweek on fertility protocols, still i have no clue if it has any negative effects to run all the time at that dose, but when it comes to hcg i believe there is a chance of overcooking the testes, 250iu eod seems according to...

Who cares if occasionally you have to punch someone in the face :D

indeed you should harness their power, want something changed, just pose as a FTM in their space and make an uprising for decent vials or whatever

Well at least it's a vial, we have to deal with ampoules with pharma stuff in europe. Options are getting sterile empty vials or keeping the stuff in a syringe and backloading into slin pins.

As a sidenote, seems you @BigTex switched TU to daily cypionate, are you doing this im or subq? Why not get an empty 10ml vial and draw all the 1ml vials in there in one session?

Good as in top of range or what? Most would be well above range on through with your protocol, are you taking enanthate or what? There is a study according to which 250iu eod produces slightly over baseline intratesticular testosterone, so take half next time.

You dont disclose your protocol, did you see how high test+hcg drove your test levels and e2, you could just be responding very well to the hcg and driving your test levels too high when using both.

Have you tried any otc creams off amazon etc?

Yes i think so too, can never get constant results from orals, and i have yet to figure out how orals always end up ruining sleep, meaning if i have taken pregnenolone in the morning, the next night i will be waking up several times. Larger doses like 50-100mg life extension give significant...

What is the situation like these days? How would you compare pregnenolone cream vs oral in terms of wellbeing?

I have taken sTfr, and transferrin while on trt and low ferritin, both checked ok, but still i can also subscribe to the camp that says they feel better after donating, could the hepcidin suppression causing iron leaking into tissues be causing stiffness and general heavy feeling, or would this...

When Did Bloodletting Start? Egyptians were among the first to perform bloodletting more than 3000 years ago. From there, the practice spread to the Greeks and Romans, then Asia, and beyond. By the Middle Ages, bloodletting was widely practiced in Europe and barbers served as pseudo-medical...

At least in my country, dht is so expensive that people rarely test it

Thanks for pointing that out, i missed the gel part.

Nice, at one point i was doing enanthate 7.5mg daily, i guess around 5.5mg test, got a through of 15nmol/l so around 430ng/dl

Yes i am familiar with this school of thought, and yes the exogenous testosterone suppressing effect on hepcidin(could lead to iron overload) is more significant in aging males and higher dosages, still you hear a lot of guys telling how they need to supplement iron on trt, go figure.

Slightly offtopic but where are your levels sitting with less than 5mg? Daily prop-enan blend or what? Iron overload on TRT, really?

So it does seem according to that study that hcg is not a DHT booster, since higher dht was found on exogenous t compared with gonadotropins group.

You stopped using pregnenolone right?

What was it that got you settled on EOD this time around?

It seems delatestryl has some chlorobutanol, never seen that in a t solution before, maybe it is in a non-relevant amount? In Europe there a couple of 250mg/ml enanthates in ampoules that have nothing but arrachis oil in them, been wondering how safe transferring it to an empty vial would be...