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Yet another potential benefit of creatine is that of an essential immune support supplement via energy for antitumor immunity. While this is a mouse model, there’s no reason to think it does not apply to humans as the cellular mechanisms are essential the same: “...our results have identified...

That's not even a high dose by female BBing standards (sadly), so I don't get that comment. Off season T use by BBers is as high as 1G per week, combined with a variety of other AAS, as well as other PEDs. None of the bbers I knew/worked with used less than 400mg per week, combined with multiple...

Great, thanx! Will order now.

Where are you purchasing your KHCO3? NaHCO3 while cheap, does taste pretty terrible and I'm very tolerant of stuff that tastes bad generally. I take taurine on and off as I remember. Only so much stuff we can take before it becomes a damn full time job!

Welcome my world. People commenting without reading, is the bane of my existence. Thanx for taking the time to read it. The buffer thing does work performance wise, and may have health implications also.

That response would suggest you didn't read the article. It's not actually that simple. There's also some interesting direct sports/performance issues to consider.

Total scam or health-promoting drink? I cover the topic below and the answer is probably not what you'd expect: One can’t throw the proverbial rock and not hit yet another obnoxious ad of some sort for alkaline water, with claims to cure all that ails ya, from genital warts to fear of flying...

Can't blame you!

Any form of regular exercise will have health benefits all things being equal. Study itself is interesting, but of little real world utility. Exercise/genetic interplay/cause and effect, etc, is still a very early science. I'm sure that at some point, they will be able to test your genes and...

How does a Testosterone Troches avoid first pass liver metabolism? Some goes into the blood via Buccal cavity, but how much? Is there data on Testosterone Troches? I found this but I'm highly skeptical and did not read the full paper to see what justifies the claim "The current state-of-the-art...

It's a summary article for non scientists. Probably have to read the actual paper for the granular details on that info. I have not read the paper myself: Treadway M. T. et al., (2019). Can’t or Won’t? Immunometabolic Constraints on Dopaminergic Drive. Trends in Cognitive Sciences. I'm...

There's a fascinating connection between inflammation, dopamine, and motivation: "Why do we feel listless when we are recovering from an illness? The answer is, apparently, that low-grade chronic inflammation interferes with the dopaminergic signaling system in the brain that motivates us to do...

Raising Oxytocin and effective strategy for combating sarcopenia? Needs more data but interesting: Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration Nat Commun. 2014 Jun 10;5:4082. doi: 10.1038/ncomms5082. The regenerative capacity of...

Ok, so do I use the oxytocin before I start drinking or after? Sounds like fun to me! o_O

I have seen that effect of reducing miles run many times. Some of the elite long distance runners I worked with had T levels of a 12 year old girl.

Our ancestors were good steady state runners and hunted some animals by simply running them into the ground, but there's probably a very small % of humans who are similar to those ancestors in stature, etc and are found in Kenya and such. There's a reason the best marathon runners tend to come...

Thirty plus years or so, I have been saying that running is the most overrated form of exercise on the planet, while resistance training (RT), the most underrated. At that time, there was little data to support that position and only dumb muscle heads lifted weights and those truly interested in...

Subjectively, I have mixed reports on the infusion. What as your dose per infusion? Some report all manner of benefits, from improved mood and sleep, to a big drop in interest in alchohol. I did three of them, and can't say I noticed anything one way or another. PS,You were seriously ripped off...

We really need some human studies to see what's going on there, that's for sure to see of those negative effects on performance transfer to humans. It's also important to note what's a benefit to anti aging/longevity does not always transfer to athletics/performance and such. They're two...

For raising NAD+ levels, not the best choice no matter what some wanna be scientists here had claimed. So far, NR appears the best choice for raising intra cellular NAD+ levels.

If HIIT, weight you can just make the distance in 20-30 seconds, 1min rest. For endurance work, strength development, etc, could be different, such as longer or shorter rest periods and such. Cant go wrong with sled work.

That depends on loading, time of the push, goals, etc. Max push for short distance will have different effects than moderate loads for longer distances and short rest periods. If you're trying to HIIT, a load that's close to max effort for 20-30s seconds of pushing, followed by 1m rest, should...

"On paper" always looked like a good idea to me, but also seemed overly $ for what it was.

Never tried one, but always thought it looked like an interesting approach to it. If it's what you have access to then by default it's good enough to do the job. I purchased my own Prowler sled and left it at the gym for other members to use, so win win for the gym. I also created the best damn...

While I agree that that the XR is way over priced, it does appear a very different animal than the basic bands that exist out there and how it's used, attachments. etc. Seems an applies oranges comparison to me. While I have not tried the X3, users seem quite happy with it. Like the TRX...

DHEA: Does It Have Non-Hormonal Benefit? Monica Mollica explores that topic via Brinkzone and it's a very interesting read: DHEA (dehydroepiandrosterone) is most known for being a pro-hormone which in the body gets converted to testosterone and estrogen. It is a long held view that DHEA...

I can't say I feel anything either and didn't really expect to.

That's really the only medically indicated reason anyone should take it, and the number of people who take DHEA minus any labs never fails to disappoint. Not different than TRT in that respect, people (rightfully) jump all over someone who starts TRT without labs, don't seem to bat and eye with...

Then that suggests it's not sensivity per se. Maybe the person you're having sex with just not pushing the right buttons, maybe your parts don't fit the way that best allows you to climax, maybe there's a part of you that does not find them sexually attractive, maybe you need to find the...

Agreed, very admirable and if such drugs help there, great.

Interesting! I'll have to look onto it some more.