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    Blood panel, how's mine look?

    By conventional standards I was never on high doses. But when I started out with 100 mg testosterone cypionate per week delivered EOD it put TT at about 1,250 ng/dL. Thanks to the influence of the late Curt Moyer I knew this was higher than I wanted, and titrated down to more like 65 mg/week...
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    Blood panel, how's mine look?

    I would guess at least 1,200-1,300 ng/dL for your peak. It is considered standard practice to test at trough, but then you do need to keep in mind that the peak is a lot higher with weekly injections. With twice-weekly injections peaks may be more like 50% over troughs. To some extent testing at...
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    I don't know the practical limitations on particle size for testosterone suspension. Maybe there's a cost-benefit tradeoff? In addition, the interest in very fast-acting testosterone is more recent and still limited. Bear in mind that testosterone basically does not dissolve in water. However...
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    Blood panel, how's mine look?

    Your instincts are good with respect to dose frequency. With once-weekly doses of testosterone cypionate it's common to have peak levels that are two to three times trough levels. This is decidedly unnatural. Assuming your lab work is at trough then you are likely going from very high to mid-low...
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    How BMI Influences Testosterone Boosts: Up-Titration Results for Oral Testosterone Undecanoate

    Apparently this study did not track free testosterone, which makes the results considerably less useful. Higher BMI is expected to correlate with lower SHBG [R], which leads to lower total testosterone for the same level of free testosterone. Therefore these cohorts with different BMIs could...
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    Clomid for Testicular Shrinkage ?

    The most common cause of thyrotoxicosis in pregnancy is gestational transient thyrotoxicosis (GTT), which occurs from the stimulatory action of human chorionic gonadotropin (HCG) on the TSH receptor. https://pmc.ncbi.nlm.nih.gov/articles/PMC4166486/ Interesting. There's always something new...
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    The significance of selegiline/(-)-deprenyl after 50 years in research and therapy (1965-2015)

    I can't say with certainty, but I think it's associated with improved mood and motivation. There are no side effects that I'm aware of.
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    I've taken the first one, which is to investigate where the missing testosterone went. It appears likely that the filtering action of a small needle is part of the problem, along with wastage via particle deposition on the vials. The empty vial that had contained 1 mL of the TS and 1 mL of...
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    Testosterone no ester

    If you're including testosterone suspension in this then yes, I am using it as a form of TRT. As documented here, I recently tried measuring the response over time. My protocol has involved injecting a nominal 1.5 mg three times a day. But based on lab work I'm beginning to suspect the actual...
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    Building a TRT protocol around hCG

    This is very much in line with my thinking, particularly the part about a longer HTPA shutdown being more problematic. In my case the addition of hCG was an improvement, but it never led to consistent libido and/or sexual function, and things still went downhill over the years. Dropping the hCG...
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    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    Lately I’ve been insinuating that some testosterone suspension products may qualify as fast-acting, and therefore be in the same league as testosterone nasal gels and buccal troches. The “fast-acting” quality is important if the goal is to retain HPTA function in the presence of exogenous...
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    Advice on next steps - mid-low free T

    I do believe that TRT in just about any form is preferable to hypogonadism. However, now that we have an increasing number of choices that are less disruptive of the overall hormonal milieu I would hope these eventually become the new standard of care.

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