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  1. Vince

    Upcoming Super Bowl Prostate Cancer Ad

    Promoting PSA Tests
  2. Vince

    More than a vitamin

    Most people think Vitamin D is “just a vitamin" Most people think Vitamin D is “just a vitamin," and, indeed, it is a vitamin… but this chart shows it behaves more like a hormone (a feature of several vitamins) that controls hundreds of processes in your body. Sunlight hits your skin → your...
  3. Vince

    Vitamin B1 (Thiamin) and ED

    We found that higher food thiamin intake was significantly associated with lower incidence of hypertension, diabetes, coronary heart disease, stroke and ED (all p trend 1.3 μg were 0.782 (0.651 to 0.940) (p<0.05). These findings suggest that dietary thiamin intake may play a protective role in...
  4. Vince

    Less carbs equals less water retention

    Scientific studies confirm that reducing carbohydrate intake leads to significant decreases in water retention, primarily due to the way the body stores energy as glycogen. When carbohydrates are absorbed, they bind to water; 1g of glycogen (carbohydrate) binds to 3g of water. If you eat a diet...
  5. Vince

    U-curve for men's belly fat and bone density

    There are many studies showing the relationship between belly fat and men bone density. This is just one. The u-curve for men's belly fat and bone density can be analyzed through body composition measurements, particularly using Dual-Energy X-ray Absorptiometry (DEXA) scans. Body Fat...
  6. Vince

    New thyroid med, once a week injection

    Potential of a drug called XP-8121. This drug is a once-weekly subcutaneous injection of levothyroxine for hypothyroidism and has a total addressable market of over $1 billion. Current treatment for hypothyroidism requires daily oral pills taken on an empty stomach, which many patients struggle...
  7. Vince

    Thyroid free t3 lowers LDL cholesterol

    Free T3 (triiodothyronine) lowers LDL cholesterol primarily by accelerating its clearance from the blood through the liver and enhancing the conversion of cholesterol into other substances for excretion. As of 2025, research highlights several key biological pathways for this effect...
  8. Vince

    That “drug” already exists—and it’s strength training.

    The statement, “That ‘drug’ already exists—and it’s strength training,” highlights the extensive and potent health benefits of resistance exercise, often described in medical literature as a form of "miracle drug" due to its wide-ranging positive effects on nearly every bodily system...
  9. Vince

    Happy people live longer!

    A new book from a renowned Harvard University doctor reveals why being happy is an even better predictor of a long life than your cholesterol levels are. Plus, his most shocking scientific discovery about how to become happy—all based on 100 years of Harvard health data. Building and...
  10. Vince

    Muscle and less hidden abdominal fat are linked to a younger biological brain age.

    Scientists discovered that more muscle and less hidden abdominal fat are linked to a younger biological brain age. Deep visceral fat appeared to accelerate brain aging, while muscle mass offered a protective effect. https://www.sciencedaily.com/releases/2025/11/251125112506.htm...
  11. Vince

    What's the u-shape for estrogen?

    I know some members complain about my high testosterone levels. Maybe it's not my T levels that makes me feel so good, maybe it's my E2 levels. Is this true? My Estradiol, Sensitive 26.7 pg/mL range 8.0-35.0, how much better could it be. What's the u-shape for estrogen? After my research it...
  12. Vince

    High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers Trial.

    This study will determine whether the presence of DNA repair deficiency in the form of alterations in the genes ATM, CDK12 or CHEK2 predicts for a high likelihood of responding to the use of intermittent high dose testosterone. This therapy may result in responses in tumors which are genetically...
  13. Vince

    vo2 max+ weight training = health

    AI Overview While weight training can contribute to overall health, it doesn't directly equate to a high VO2 max, which is a measure of aerobic capacity. Weight training primarily improves strength and muscle mass, while VO2 max is more closely linked to cardiovascular fitness and endurance...
  14. Vince

    Shorter men may have a protective FOX03 gene:

    For longevity, men who are shorter tend to live longer than taller men. Studies suggest that men under 5'4" or even 5'2" may have a protective advantage, potentially due to factors like the FOX03 gene and lower fasting insulin levels, according to Healthline. The FOXO3 gene plays a significant...
  15. Vince

    103-year-old man from Ohio.

    At the age of 69, he was diagnosed with cancer and given only three months to live by doctors. Instead of accepting this prognosis and undergoing surgery, Mike decided to take a different approach and embraced a plant-based macrobiotic diet inspired by "The Cancer Prevention Diet" by Michio...
  16. Vince

    Is this real?

    Russia announces good news about the cancer vaccine. Alexander Gintsburg, the director of the Russian 'Gamalei' Center for Epidemiology and Microbiology, stated:This is a highly specialized product where a vaccine is designed specifically for each patient, and the reason for this is that each...
  17. Vince

    Overthinking

    Overthinking involves excessive rumination on thoughts and situations, often leading to distress and difficulty with decision-making. It can be a symptom of anxiety, depression, or other mental health conditions, but can also be a learned behavior or a response to stress. Strategies for managing...
  18. Vince

    VO2 Max: The Gold Standard

    AI Overview While both VO2 max and strength are strong indicators of longevity, VO2 max is considered the most robust predictor. However, strength, alongside muscle mass, plays a significant role in overall health and lifespan. VO2 Max: The Gold Standard Definition: VO2 max, or maximal...
  19. Vince

    3 hours of sleep and no fatigue?

    For decades, the mantra has been the same: adults should aim for seven to eight hours of uninterrupted sleep each night for optimal health, performance, and longevity. From doctors to wellness influencers, the message has echoed across platforms, backed by countless studies linking insufficient...
  20. Vince

    6 symptoms of high cholesterol seen in body and face

    https://timesofindia-indiatimes-com.cdn.ampproject.org/v/s/timesofindia.indiatimes.com/life-style/health-fitness/health-news/6-symptoms-of-high-cholesterol-seen-in-body-and-face/amp_etphotostory/121353053.cms?amp_gsa=1&amp_js_v=a9&usqp=mq331AQGsAEggAID#amp_tf=From%20%251%24s&aoh=17480105620220&cs...
  21. Vince

    subcutaneous injection for treating hypothyroidism.

    I thought this was interesting. A Sub-Q injection for hypothyroidism. It's in phase 3, see what happens if it makes it to phase 4. XP-8121, a Phase 3-ready, once-weekly subcutaneous injection for hypothyroidism...
  22. Vince

    secret of ‘Blue Zones’ Fake data,

    For a quarter-century, researchers and the general public have sought to understand why people in so-called “Blue Zones” live to 100 at far greater rates than anywhere else. Saul Newman, a researcher at the University College London (UCL), believes he has the answer: actually, they don’t...
  23. Vince

    Combining two cholesterol-lowering drugs.

    Even though this is a very touchy subject, I found this interesting. The largest analysis to examine the best way to lower levels of "bad" cholesterol in patients with blocked arteries shows that they should immediately be given a combination of a statin and another drug called ezetimibe...
  24. Vince

    The Powerful Mitochondrial Effects of Nitrates

  25. Vince

    Plastic and lower testosterone levels in young men

    AI Overview Yes, there's evidence suggesting that exposure to certain chemicals found in plastics, particularly phthalates, can be associated with lower testosterone levels in men, especially in younger age groups. Here's a more detailed explanation: Phthalates and Testosterone: Phthalates...
  26. Vince

    Sleep deprivation impacts us in various ways

    There have been quite a few research studies on lack of sleep, like how it can increase the risk of heart attack and stroke, contribute to brain aging, and even make you feel drunk at work (not as fun as it sounds.) If you don’t get enough REM sleep, your brain has trouble maintaining all sorts...
  27. Vince

    Surgeon General Calls for Cancer Warning Labels on Alcohol

    I didn't know alcohol contributes to cancer.
  28. Vince

    The danger of doing your own research.

    In 1995, McArthur Wheeler and Clifton Earl Johnson robbed two banks in Pittsburgh. They believed they wouldn't be caught because they had researched how to render themselves invisible to bank security cameras. They learned that lemon juice could be used to write an invisible message on paper...
  29. Vince

    Some foods may increase the risk of prostate cancer, while others may help reduce the risk.

    Some foods may increase the risk of prostate cancer, while others may help reduce the risk: Red and processed meat Eating red meat, like beef, pork, lamb, or goat, and processed meat, like bacon, ham, and sausage, may increase the risk of prostate cancer. This may be due to heterocyclic...
  30. Vince

    A Stanford-led team discovered a new ketosis pathway.

    The ketogenic diet, commonly known as “keto,” and intermittent fasting have gained widespread popularity, attracting everyone from casual fitness enthusiasts to endurance athletes. Both approaches aim to leverage ketosis — a metabolic state in which the body burns fat for energy instead of...
  31. Vince

    The Loss of Estradiol by Androgen Deprivation in Prostate Cancer Patients Shows the Importance of Estrogens in Males

    The role of estradiol (E2; an estrogen) in men needs to be more appreciated. In this review, we address the clinical situations that allow the study of the clinical consequences of E2 deficiency in men and discuss the effects of restoration of levels of this reproductive steroid hormone. In men...

Beyond Testosterone Podcast

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