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Still taking it first thing in the am. Most hormones really peak in the am, including testosterone, thyroid, DHEA, cortisol, aldosterone, progesterone and I’m pretty sure Pregnenolone as well, melatonin and I believe GH are mostly secreted at night.

we want to put this in context, or I should probably say with a better word in balance. I like the pic you attached because it really shows both sides. Too much Progesterone can certainly inhibit the "excitation of desire" side, but we don't want to be too much in that side either, that may...

I started injecting 1.5mg subQ at bed time, and 12 hrs after my Pro level came back at .2, (starting level was .1) My doc guessed the peak at .4/5. I have never measured the 2.5mg Because some insomnia I was having, which turned out to be Thyroid related, doc suggested to do the Pro in the am...

I thought I was doing well for sometime with the oral micronized pregnenolone, but later on I realized it was inconsistent. This because taking pregnenolone orally is going to be converted in bulk to Preg-S and Progesterone/Allopregn and who knows how many other metabolites. Sometime it may...

I can tell the 2.5mg got me really wild, sex drive and sexual thoughts were too much, like in an unnatural way, fun but just too much. I’m down to 1.5mg again, I’m going to test level at peak now. In this video at 24:27 is also reported the effect of TRT on Progesteorne level. However, levels...

I haven't' use Pregnenolone in a while. You need to try and see what works better for you. I think cream is a better choice than capsules

Progesterone is a hormone like other, it needs to be addressed if deficient.

Hi Vince I thought you were using Pregnyl till little while ago, do you see any differences from Pregnyl to ReliableRX HCG? that is a huge saving on HCG at the end of the year

good to see this post, I was just running into the same issue.

When I hear about Progest decreasing libido, I think about either the Pro having an effect on E2, or possibly just too much of it. I think many try things without knowing their levels or if they really need it. There was a guy in the forum, stating that anytime he uses Prog his E2 will crash, we...

according to Leo (RIP), Allopregnenolone is strongly involved in male sex drive, probably why then many have reported increased sex drive from Progesterone. I noticed this too in the past with the Pregnenolone capsules. He estimates a 16mg daily dose, I assume orally, for those on TRT, which...

yes my libido improved as well

have you measure Prog level before and after? as far as erection, I even think it works better than cialis, not joking. it seems like my penis is bigger, ticker harder on the progesterone, crazy. I'm not sure it does this directly or indirectly trough metabolizes., libido is great too. I did...

so far, the injectable Progest, that is the hormone that gave me the more sex drive, erection and libido, I think even more than Testosterone

@FunkOdyssey any updates on your injectable Progesterone trial? I had my follow up with doc last week, and we discussed my Progesterone levels coming back at .2 ng/dl on the 1.5mg Inj Progest, he mentioned how the peak could be at 1 to 2 hrs post injection, and predicted a peak level of .4/.5...

That’s could be one the reasons for sure, I could see the acne on my back clearing up nicely. I also notice my skin looking softer and maybe more moisturized, progesterone is upstream of aldosterone, or perhaps it has some mineralocorticoid properties as well, helping with cellular hydration

I see the same benefits in regards to the skin.

How long how you been on the Prog cream before testing the E2?

I would think this applies at higher supraphysiological levels/dosing

Perhaps @Cataceous can clarify this, but I believe he did start with 2.6 mg and that brought his Progesterone to .9 ng/ml, now using .6mg and Prog sits at .3 ng .ml By the way, I have been doing 2.5mg for the past two days, and it does make me feel groggy like drugged feeling similar to the...

You are right. However, I believe ACTH can also start or participate in those enzymatic processes just like LH. Perhaps HCG is needed in men on TRT to reactivate fully that pathway. I just increased my Progesterone, I will report any changes in my Testosterone if there are any

then if we see a Testosterone increase with Progesterone, it makes sense thinking that Progesterone directly converted into Testosterone. I have seen this happening to some people with oral Pregnenolone while on TRT

@Gman86 I hope you don't mind my questions. You mentioned that 2mg of the injectable Progesterone brought the level to over 1.0 ng/ml, but if I understand well you already started with a baseline of more than .1ng/ml correct? just considering the start test method, basically you were not...

we are talking about it here What has been your experience with progesterone?

possibly, I believe I have seen my FT increasing a bit while on the scrotal Prog cream, maybe just because the anti aromatizing properties of Progest

@Gman86 I’m curious to know if you have ever seen an increase in testosterone with Progesterone supplementation

@Cataceous what laboratory and test method have you used to test your Progesterone?

Perhaps, using a different test method, yields to a different ref range for the “average” male progesterone level. This is why we shouldn’t compare two different test method even if the same unit was used, like in this case the ng/ml. We probably shouldn’t even compare same test method from two...

@Gman86 I have always been using LabCorp for all my Progesterone tests for years, and I always used the same test method, which should be the Electrochemiluminescence immunoassay (ECLIA). Range is .0ng/ml to .5ng/ml as today. Obviously here in the US There have been many men I have seen on TRT...

@Gman86 an update on the injectable Progesterone, 1.5mg daily SQ brought my Progesterone to .2 ng/ml from .1. I measured it in the am, probably about 13 hours post injection. You guys responded better with this dosage, I had same issue injecting Testosterone SubQ in the past. Something...

give it two weeks, then pull some labs as well. I could notice I believe after a week, more sex drive, better erections and libido, sleeping better and feeling calmer. I also noticed my skin cleared up a bit, especially the acne on my back. I started with 1.5 mg, I'm pulling some lab next week...