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Yes. It's just like when you put a muscle in a cast. It/They atrophy from lack of use

I agree with Phil. Also, in many years of observing the hormone space, AIs seem to be the single highest risk for causing major hard-to-resolve issues, so doing other things, like splitting dosages, adjusting dosages, changing ester/formulation, and using other things that have a mild AI affect...

Another option is to supplement things that act like and AI such as Zinc, melatonin and Cialis, but which don't seem to have the excessive and unpredictable downsides of AIs, and go by symptoms from there. I have the opposite problem of trying to raise E2 so I have been on the lookout to avoid...

yes, several days per week usually

If soreness is your primary issue, it’s possible that lack of anabolism is part of the problem, but it sounds like your protocol should be doable without much soreness. Jumping to Oxandrolone before ruling out some other fundamental issues seems a bit premature so before you jump to that I would...

I would try it and see. A lot will depend on your how recovery-friendly your lifting protocol is. I (almost) never do a set to failure, but I do a lot of near-maximal sets and I have found that this massively reduces the recovery time needed while also letting me do far more near-maximal volume...

I just went back and read your initial post, and unless I missed it somewhere else, I don't see where you've done a thorough check-up with a Holistic/Integrative Doc, someone who would check for nutrient status, long-term infections (e.g. lyme) and other things that could cause your symptoms...

I cut the pills in half. They are quite small but they could be cut again with a pill splitter but I am fine with the 2.5 mg dose, at least in theory since I don't feel anything similar to Gman.

Yes. It's not going to do as much as that plus other anabolics, however I think it's a viable approach if one want a moderate boost. Many people who start TRT looking primarily for gym gains should IMO start with some sort of minimally suppressive protocol such as enclomiphene/oxandrolone...

FWIW, I've found the same thing when I cut my dose of Test cyp, at least in the short term. I would do so permanently and add in Oxandrolone for the anabolic effects, except that my E2 is already very low and I haven't wanted to get into supplementing E2 directly.

Have you run into any strategies for raising E2 in those of us who are perpetually low? I use HCG and my T is high normal but E2 is constantly very low.

I agree with Funk on the Berberine. Also, there is some evidence that lowering protein may help, and there has been a lot of discussion of that recently in relation to the Sugar Diet (which has been around for decades but has recently be re-publicized). It's not something I think it is viable...

I'm increasingly thinking, both from my own experience and observing others, that what you are describing makes the most sense, but with the addition of other targeted compounds to address specific issues. In your case, a moderate dose of Oxandrolone to replace the "lost" T seems logical (or...

The time for high Vitamin C supplementation no matter what is if you feel any kind of infection/illness coming on. Especially Liposomal Vitamin C. Vitamin C is like the ammo for your innate immune system "gun". It's interesting that it may have raised your HCT since some of us struggle with...

Thanks for posting this. One of the big problems with what I'll call the Minimally Suppressive Testosterone/SERM approaches is the lack of publicly available discussion on the results of such experimentation, so it's interesting to see your results. I had never heard of L-Tyrosine creating those...

I have found that the 250mg version doesn't have even 1 quarter of the flush off the 500 version, so I have switched to taking more of the 250's.

It can make some people smell like Garlic for a little while although I've never had this issue. It does not affect libido. You have to make sure the skiin is clean in the area you apply it. AMidwesternDoctor on substack has done a massive series on it and I suggest you read that. It can...

You might also try DMSO which seems to benefit just about everything.

This is just a wild guess on my part, but a vacuum penis pump might be worth a try. The concept would be that it draws blood into the penis and the increased blood flow might be therapeutic. There was also a study posted here a while back that said Hyperbaric Oxygen Therapy increased vascular...

Several things: - Time Restricted Eating is essential no matter what. Specifically, start by eating within an 8 hour time window so that your are only drinking water for 16 hours per day. Part of insulin resistance appears to be that cells are over-stimulated by constant exposure to insulin, so...

You are making a claim that does not seem to be supported by evidence or logic, so you you need to cite some or expect your position to be challenged. For example, aromatizing compounds are well-known to lead to gyno in some people and be countered by an AI. Gyno is at least partially fat...

I can't remember if I mentioned this before but have you tried timed-release melatonin for sleep? It sounds like some sort of dopamine or cortisol issue but melatonin might help. A spoonful of quality honey before be d might also help if it a low blood sugar issue. Also, I've run across several...

Stress can certainly impact cortisol, so it sounds like that is a prime candidate for your issues. When dealing with any difficult issue however, you want have everything working in your favor, and you want most stored fat in your body to be saturated fat, not PUFAs. Resolution of cellulite is...

I've never used this product but I do use 100% DMSO all the time and it can certainly be a little harsh on the skin in some places. Mixing whatever your normal dose of alphagels with the 70%DMSO/30% aloe-vera blend might reduce the skin issues.

Thanks for posting this. This implies that blood pressure should rise if blood viscosity is in fact rising in a problematic way, however I've had a mysterious rise in HCT with no rise in BP that I can tell. I'm wondering (hoping) that perhaps BP can be used as a way to tell if a rise in HCT is a...

Have you eliminated all seed oils from your diet? Do you have any reason to think your cortisol may have increased? High cortisol can cause abnormal fat deposits (see Cushings Syndrome/Disease).

Personally, if they're the only source, I wouldn't let this scare me away. There's nothing wrong with DMSO and if the DHT works then it works. MT-2 was known to be under-dosed from the non-US/CA sources but it is so strong and you have to dose by experimentation anyway so it doesn't really matter.

"Testosterone stimulates the production of red blood cells (erythropoiesis) by initially increasing erythropoietin (EPO), establishing a new EPO/hemoglobin "set point," This seems underappreciated and could explain why some of us have our HCT jump up and stay up for no apparent reason. On the...

Is it possible you were under-hydrated for the test where your HCT was higher? That could do it.

The issue with sleep and keto (i had the same issue) as I understand it is low blood sugar episodes provoking cortisol release at night which puts the body into an awakened state. You can having your carbs late evening, or having a large serving of glycine late evening. I went away from strict...

I agree with the direction Funk is suggesting which is to look for root cause issues. If viagra is not working that suggests a lack of Nitric Oxide production, so things like Beet Root powder, Nitric Oxide tablets, sunshine and HIIT would be good to try. Bi-mix or Tri-mix would be another option...