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Check out the lifting dermatologist on YouTube.

“I swear, honey - it tastes like cotton candy…”

I forgot to ask - is all being applied on the scrotum?

@FunkOdyssey, I was thinking about you recently, so this is good timing. Glad to hear it. Scroll up and you'll see my labs, which look nearly identical to yours. I felt pretty bad at those levels. I have since modified the protocol and currently also feel pretty good on cream. The reason I was...

I love it. I take it like i’m being nudged by a brother! Sorry to hear you’re dealing with mood issues. Jury is still out for me. I am battling fatigue. In the process of dropping dose to see if it gets better. After doing some reading, it looks like I got put on a high dose pretty damn quickly...

I actually have stuck with various protocols for extended periods of time. Just in the last 2 years, I’ve struggled. I am currently on cream. been on it pretty much for the last 3 to 4 weeks.

Wait - @Charliebizz, didn’t I specifically ask that you not jump on me?!? ;)

Getting to the root cause is critical. I definitely agree with you on that. I’ve taken to a lot of contemplative leaning teachings, which has been helpful.

Appreciate the thoughts. My bad - I wasn’t clear. I am tapering the SSRI, not TRT! The gut is and diet are definitely important!

@readalot and I have been discussing SSRI's in another thread, so I thought I'd move it over here. I started sertraline 50mg for four days followed by 100mg for the last few weeks. So far, the biggest challenge has been crushing fatigue in the middle of the day. It starts around 11 AM and...

I do feel less anxious (I am also tightly wound). But, the fatigue is unacceptable for me. Maybe with time it will subside? For now, I am actually titrating down - primarily to troubleshoot the cause of the fatigue with the idea that I can always go back up and/or restart. Some say the combo of...

I'll dig in. Thanks. Mood was one of the many symptoms I have been trying to "treat" with TRT. As is well documented, I have had a hard time nailing down a tolerable TRT protocol (@Charliebizz, hold your fire, my brother ;)). So, I decided that maybe I should be attempting to attack mood from...

I actually may consider this, too. Any idea why Lexapro would be useful for this as opposed to any other SSRI? Any unpleasant side effects from it (I know it can be associated with emotional blunting, libido, drop, etc.)?

Nebivolol is supposed to have less sedating and libido affects. It might be a good option if you have those side effects. Reasonable to ask your prescribing physician, particularly since you are on an ARB.

I think this is more common than we think. I have experienced it as well. The few things that were helpful: Using Natesto or using a beta blocker with your current protocol. Beta blockers are great drugs, but for some, they can come with unacceptable side effects (lethargy, depression, libido...

It’s theoretically possible that the preservatives are causing a problem, but unlikely. One way to test the theory would be to Xyosted. It does not have preservatives. It would be an expensive experiment if it’s not covered by insurance.

Yes. Cream and I have a bit of a love-hate relationship. It can be a wild pony to tame, but for many, it’s an excellent treatment option. If you’re not careful, you can skyrocket your testosterone and DHT level with cream. But, it still may be worth trying. If you can get a compounded cream...

This should definitely be taken seriously. Get a high-quality cuff for home. Measure it a few different times during the day and do that consistently and record the values. If you are seeing it that high on a consistent basis, you should press your primary care doctor to address it.

I experience similar sensations, depending on what form of TRT I am using. You might consider trying a different form or changing up the dosing and/or frequency like others suggested. This tends not to be an issue for me with things like Natesto. It’s worth trying something else such as a...

That’s a hotly debated topic.

Are you having high estradiol symptoms? If so, what are they?

So, to be clear, you are or are not using cream?

I’ve used it on and off for years. I can bore you to death with details. Bottom line is I think for it to work, you have to give it time and be patient. It’s the least likely to cause side effects, which is great.

Not really. If I apply it to my arms in the morning, I get dressed, go to work and I'm covered. My understanding is that transference is unlikely beyond several hours. Edit: sorry - I just saw this question was not for me!

Interesting. Same DHT levels? What were they?

Those that switch from cream to injections seem to be guys that don't absorb cream well. It appears that you absorb it well. So do I. In fact, I am trying cream again right now. My issue is figuring out a way to not absorb too much. There are various reasons why a guy may switch from injections...

@Cataceous, I read either in this thread or another one that you tried transdermal and had disproportionate conversion to DHT. Were are you applying to scrotum or extremities? Also, do you have any way to make an educated guess as to how long it might take DHT to normalize if you were using a...

What dose and where were you applying? How many times a day? I recently posted my labs on a somewhat modest dose on the scrotum. Labs were crazy out of whack. Lots of people have gone from cream to injections and vice versa.

The IM arm of the study is a pretty archaic protocol. That said, this is an important find. I‘d love to see more guys try Natesto - in particular guys who can’t dial in on anything else.

My intention in posting my original labs was not to blame E2, but just to provide information and feedback to the community at large. I do think elevated E2 gives me problems. I’ve experienced it before. That said, I believe the substantial elevation of testosterone, and all the associated...

My free T was double the high end of normal. Maybe some can tolerate that, but I definitely cannot.