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Defy Medical TRT clinic doctor
  1. S

    Optimizing Oral Testosterone Undecanoate (Kyzatrex) TRT: All You Need to Know

    Ok, I did 400 mg kyzatrex at 8 am, pulled labs at 12:30pm: what’s going on!?!?
  2. S

    Kyzatrex or Jatenzo

    Dirx was a horrible experience, I had to submit the info 3 times, they cancelled it each time, never gave an explanation. I would never use them again, I use revive now, much better
  3. S

    Optimizing Oral Testosterone Undecanoate (Kyzatrex) TRT: All You Need to Know

    If 50 mg test a week is making you feel horrible, why continue? Bump up to 100 or so and just donate blood every 2 months.
  4. S

    Rises in Hematocrit is Associated with An Increased Risk of Cardiac Events in Men Starting Testosterone Therapy

    My HCT was 47.5 in my 20s, now at 46 and on trt for 6 years my HCT is 50.3 despite blood donation last month. I figure I’ll do another donation in 2 weeks. Then, I should take iron cause my ferritin is low, which seems counterproductive
  5. S

    Optimizing Oral Testosterone Undecanoate (Kyzatrex) TRT: All You Need to Know

    What do you mean by your last statement? If you look at a few studies, 50 mg testosterone per week only lowered LH by 35%. My thought is having a baseline test say at 350-400ng/dL (from the 50 mg testosterone cypionate), then augmenting with kyzatrex at 7 am and 1 pm, while taking enclomiphene...
  6. S

    Optimizing Oral Testosterone Undecanoate (Kyzatrex) TRT: All You Need to Know

    So I’m going this now, I’ll repeat back with labs in about a month..
  7. S

    Any us pharmacy has HMG or FSH?

    Are those peptide sites legit for it?
  8. S

    Any us pharmacy has HMG or FSH?

    Anyone have any luck getting either? Revive had fsh but can’t ship to me since it’s now considered a “biologic.”
  9. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    Well said. That’s why I switching to kyzatrex, my free T was well over the limit on 100 mg cyp per week. The doc told me to go up to 140 since my “dose was so low.” I’m now focused on longevity and seems healthier to have more natural peaks and troughs and normal free T levels
  10. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    Yes. Thank you for that. My point though was if those guys had sub 800 levels, I’d hate to do half the dose, as I already feel tired and brain fog on the 400 bid regimen. I’m going to give it 2 more weeks then check labs. I’ll check right before my afternoon dose around 1pm, sound reasonable?
  11. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    Agree. Also I was basing my numbers off the article below where men taking 400 bid has TT of just under 800: https://www.urologytimes.com/view/higher-initial-dose-of-oral-testosterone-undecanoate-appears-safe-efficacious
  12. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    My thought process was LH I believe was 1.9 on the guys taking 400 bid so if I had the dosing spaced together during the day I would feel better then allow the enclomiphene to work better at night when I was lower. Ie I feel like there isn’t a great reason for me to take my kyzatrex at night...
  13. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    So I should do 400 mg at 7 am and 1pm? That way I have low troughs overnight to allow the enclomiphene to work better?
  14. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    My levels at 29 were around 300. But I’m not aiming for that anytime soon
  15. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    You feel ok with TT of 1400 in terms of health and longevity?
  16. S

    Oral testosterone. Who's on it?

    I’m on kyzatrex, I take 200 mg at 7 am, 9 am, noon and 2 pm. My goal is to have stable levels through the day, then low levels while I sleep. I take 12.5 mg enclomiphene at 7 pm , so my goal is to increase my LH on this regimen …
  17. S

    Kyzatrex - sudden emptiness feeling in head

    Any updates? Blood levels on 400 bid, still on kyzatrex?
  18. S

    Adding Kyzatrex (Oral Testosterone) to Clomiphene (Clomid) Improved Symptoms in Non-Responder Men

    I’m doing 400 mg kyzatrex at 7 am, 200 mg at noon and 200 mg at 1 pm (to lessen the peaks), 12.5 enclomiphene at 7 pm… if you plot out TT, it’ll be 7-800 until around 5pm then drops to around 300 at night which should allow the enclomiphene to work:
  19. S

    Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

    Right. I injected 11mg at 7 am and at 3 pm my TT was 954. I switched to kyzatrex 400 bid but i definitely feel tired abd brain fog, but I’m giving it longer to see if my body has to adjust. 9 days in so far?
  20. S

    My results on daily prop 11mg SQ

    Thanks, crazy how we don’t know much about prostate cancer. Time to up the dose, lol (joking)
  21. S

    My results on daily prop 11mg SQ

    I wonder if estrogen is the cause? Not sure. One thing I find with prostate cancer is most of the people I know who have prostate cancer have 2 things in common, huge guts and jobs that required a lot of sitting…. Maybe that causes the inflammation that triggers the cancer
  22. S

    My results on daily prop 11mg SQ

    https://www.ndph.ox.ac.uk/news/high-levels-of-two-hormones-in-the-blood-raise-prostate-cancer-risk#:~:text=In%2520the%2520population%2520as%2520a,strategies%2520for%2520preventing%2520the%2520disease.%E2%80%9D...
  23. S

    My results on daily prop 11mg SQ

    What about the increase in prostate cancer with higher free T? Also, isn’t dose irrelevant, the labs (ie total T etc) are more of a guide for trt? I did a single shot of 200 mg test cyp and 5 days after inject my total testosterone was 2100!
  24. S

    My results on daily prop 11mg SQ

    It’s test prop, so yea I think 7 am injection it was a good idea to check at 3pm, as I inject daily. And yes I think lowering my free testosterone to normal ranges is healthier, what am I missing here?
  25. S

    My results on daily prop 11mg SQ

    No libido issues. But if I lower dose I think estrogen will decrease. I’ll drop to 8 mg and recheck
  26. S

    My results on daily prop 11mg SQ

    Just to be healthier, scared about prostate cancer, long term supraphysiologic levels etc
  27. S

    My results on daily prop 11mg SQ

    So I’m doing only 11mg test prop QAM, and my results are below. I’m guessing decrease dose to 8 mg daily… Thoughts, advice?
  28. S

    Solvent-free propionate: finally a successful protocol for me!

    Post labs when you get them
  29. S

    Optimizing Oral Testosterone Undecanoate (Kyzatrex) TRT: All You Need to Know

    I was thinking the same thing, like 25 mg test cup SQ twice a week and only using 400 mg kyzatrx in am
  30. S

    Adding Kyzatrex (Oral Testosterone) to Clomiphene (Clomid) Improved Symptoms in Non-Responder Men

    Wonder if I can do 600 mg in am, and clomid at night, I don’t see any pharmokinetics on 400 bid or 600 once a day…
  31. S

    Adding Kyzatrex (Oral Testosterone) to Clomiphene (Clomid) Improved Symptoms in Non-Responder Men

    Crazy thing to me is that 400 mg in am plus 25 mg clomid at night increased TT more (around 1000 ng/dL) than the 400 BID dosing (looks like TT was around 7-800 in this group). Am I wrong?
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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