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Defy Medical TRT clinic doctor
  1. W

    Advice on next steps - mid-low free T

    Doc - my educated guess it that exogenous T is not the answer to your problems especially considering many of us would kill your natural blood test numbers. Your symptoms are more in line with overtraining.
  2. W

    Testosterone dropped after a few months on the same dose

    Do you feel any different now versus period of first test (not including the initial honeymoon period)?
  3. W

    Xyosted Prefilled Autoinjector for Subcutaneous Testosterone Administration

    I actually tried it at one point because I had read Xyosted contained no preservatives. I had given myself hundreds of subq inejctions before Xyosted and damned if I couldn't get that auto-injector to work. I just don't have enough belly fat. It was comical. I later thought about filling...
  4. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Apologies for getting off thread topic, but can you provide more details on wife's protocol? Sounds like 2-2.5 mg E3.5 days shallow IM, correct? What ester is she using?
  5. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    So I take it your sleep eventually normalized at the higher doses?
  6. W

    Madmans pick BD 28G LDS insulin syringe/permanently attached Micro-Fine™ IV Lo-Dose™ thin-wall needle - Delivers 27G Flow Rate

    And don't forget BD's 31 gauge ! https://www.excelmale.com/threads/daily-subqers-5-stars-for-bd-ultra-fine-insulin-syringe-31g-3-10cc-5-16.24643/
  7. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Interesting. Admittedly, I have not tried to power through that feeling because the heart palpitations freak me out. But its something for me to keep in mind. Have you found the side effects eventually dissipate with such a large dose? I recall you quitting TRT early on because you felt...
  8. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    What fascinates me is how some guys are able to tolerate large daily doses and still function normally at supraphysiologic levels. For example, a mere 10mg of daily prop felt like speed to me. Difficult to concentrate; too wired to sleep; heart palpitations, etc. And yet some guys can take...
  9. W

    About to Start a New Protocol

    and should be a lot cheaper.
  10. W

    About to Start a New Protocol

    I didn't realize your recent test numbers were on Xyosted 75m 1x weekly. That is impressive how little TT dropped from mid-week to trough. Why didn't you stay on the 50mg Xyosted? Total-T: 1129 (250-1100) tested at mid-point Total-T: 1102 (250 - 1100) tested at trough
  11. W

    About to Start a New Protocol

    When in doubt, minimize the variables. May want to take a break from Tadalifil while you adjust to new dosing schedule. I have had similar low E2 issues, but never done anything about it. I've read some accounts of guys trying to microdose estradiol cream.
  12. W

    Shallow Testosterone IM versus SubQ Injections - Lab Results

    Where are injecting subq other then belly area?
  13. W

    Shallow Testosterone IM versus SubQ Injections - Lab Results

    Thanks for clarifying madman. Maybe that is why no one talks about it lol. I was thinking about role of lymphatic system after several very strange subq experiences with Test Suspension where I felt physically sick, but did not experience that same side effect with IM. But as you know...
  14. W

    Shallow Testosterone IM versus SubQ Injections - Lab Results

    Its also about convenience. Guys who are injecting small amounts daily often choose subq because its so easy - 5/16 into belly fat you don't even feel it. That's important is you are doing hundreds of injections every year (and thousands over a lifetime). One thing that get little attention...
  15. W

    About to Start a New Protocol

    Keep it simple. Split your current weekly dose in two. Your levels are plenty high enough already. Don't mess with HCG until you iron out your new E3.5 days protocol
  16. W

    Dhea and pregnelone

    FYI, Pure Encapsulations makes a 5mg DHEA capsule that allows for lower dosing
  17. W

    Updated Labs - Help Please

    For EOD, you may want to keep it simple and just double to dose. If it were me, I would lower the dose regardless of frequency, but then again I don't do well at top of TT range.
  18. W

    Updated Labs - Help Please

    If you feel better on shallow IM, why not try injecting EOD instead of daily to make it more doable? Some guys seem to like EOD. Also, you may want to reduce HCG. Many including myself feel like garbage on it. Keep on experimenting! (although most would say give it 8 weeks between...
  19. W

    Coming off after 10 years non stop self administered "trt" MISSION IMPOSSIBLE RECOVERY

    Why not work your way down gradually before going cold turkey? You are in for a rough ride (but you know that already)
  20. W

    22 yr Old Low E2, 0 Libido

    Normal range E2 / TT ratio is around 0.3-0.6%. Even with TRT (low dose), I tend to hover around 0.25 - 0.30% so on low side. My TRT clinic was reluctant to suggest using estradiol product because its apparently easy to overdo it. As alternative, they suggested supplementing with DHEA to...
  21. W

    Starting TRT Soon

    Has your A-fib gone away since reducing dose? Early on in my TRT journey, I experienced a bounding heart for several days while I was at high end TT on trough day. It spooked me so I reduced dose and sure enough the problem went away thankfully. Not the same as A-fib, but just another...
  22. W

    Glucosamine - my devastating side effects.

    Glad to hear you are feeling better, but 5 days is not much time. It would be good to see update in 1-2 months
  23. W

    10 Years on TRT and Only Recent Libido Issues

    The libido issues started on your old protocol? Increasing the dose to supraphysiologic levels never seems to work and can even make it worse.
  24. W

    Starting TRT Soon

    The beauty of self-administering your injections is that you ultimately control the dose. I am also low dose guy (7-8 mg per day) and have so much leftover T in my vials its kind of ridiculous. You won't need the AI if you start at reasonable dose.
  25. W

    Compounding Pharmacies and Test Raws and Tariffs

    What is the UGL situation you refer to with the Chinese production facilities for the raw powder? I would not expect any interruption in supply to last long. There is so much $$ involved driven by worldwide demand
  26. W

    Injection frequency & effects on other issues

    When you are only drawing 7-8mg TE daily, its nothing.
  27. W

    Injection frequency & effects on other issues

    Most daily guys inject Subq with small 5/16" 31 gauge needles. You don't even feel it. Are you currently injecting IM? Reducing dose usually helps with sleep. Although my sleep sucks even on low dose and I've been on daily TRT for years lol. What is your weekly dose?
  28. W

    Testosterone Side Effects after one year.

    I am same way - even 8mg of TE results in early AM awakenings. Just a wired feeling with steady state. Regarding the blend, here is long thread. I no longer blend and instead do two separate injections - one TE and the other TP. Same idea. No big deal with 31 gauge 5/16 insulin syringes for...
  29. W

    My optimal protocol is daily injections of Estrogen and just 24.5mg Test per week

    Are still injecting estradiol? If yes, what is your latest protocol?
  30. W

    Difference between daily IM vs daily SubQ?

    Some guys seem to do well on the higher ED doses, but I am definitely not one of them. From the many accounts I've read, even 10mg of TE/TC will put most guys at top of TT range. There is a very long thread on another forum by a bodybuilder talking about the potency of 10mg per day. If you...
  31. W

    My new blood test on test phenylpropionate

    Did you feel any difference when you switched from phenylpropionate to TE/TC?
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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