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  1. H

    How can I raise my E2 level?

    Interesting. I figured that weekly injections would leave me with lower E2 levels by the end of the week. Either way, weekly T injections only got me up to a 9. Thanks Nelson, I'll talk to my doctor about raising the dose for one or both of my meds. At this point it's still early in my...
  2. H

    How can I raise my E2 level?

    Correct, I'm not taking an AI. I dose my T once weekly. Wouldn't splitting the dose keep my E2 at a more consistent level? By injecting once per week I should get a spike after injection and then wouldn't it fall much lower by the end of the week? I haven't been working out much lately due...
  3. H

    How can I raise my E2 level?

    Total was 700 (348-1197)
  4. H

    How can I raise my E2 level?

    Recent bloodwork showed that my sensitive E2 level is at a 9 (3-70). Labs were drawn 5 days after my T injection. I was definitely taken aback by this, as most guys have the opposite problem while on TRT. My protocol: -100mg test cyp EW -250iu hCG 2x/wk I feel terrible. My T levels are...
  5. H

    acne increase on T

    Have you had your estradiol levels checked recently? Elevated E2 usually seems to be the cause of acne while on TRT.
  6. H

    Mixed Pregnyl (HCG)

    Thanks Nelson! Have you noticed any increase in your E2 on this protocol?
  7. H

    Mixed Pregnyl (HCG)

    What is the consensus on when to inject hCG while on TRT? Some say on days 5 and 6 before the weekly test injection. Others seem to prefer that the doses are spaced out a bit more between injections. Which have you found to be more effective?
  8. H

    Needle phobe, questions about giving HCG injections - I know, I sound like a big baby!

    Yes, just clean the site and you're good to go. When you switched brands of hCG, are you sure that it was the same concentration of the medication? Seems odd that you'd have such a drastic change from subQ to IM.
  9. H

    Needle phobe, questions about giving HCG injections - I know, I sound like a big baby!

    Once the needle goes in, aspirate (pull back on the plunger a little bit) to see if you're in a vein. If there is significant blood in the syringe you may be in a vein. Withdraw the needle and try again.
  10. H

    New Guy Here. TRT has been prescribed--but does my bloodwork warrant it?

    If you're going to start out on 150mg/wk, talk to your doctor about splitting the injections into 75mg/E3.5D to ensure that your E2 stays in check. If you can avoid having to take an AI, that would be ideal.
  11. H

    Are 1" needles ok to use for glute injections?

    I did some Googling and found conflicting opinions about this. Some say that a 1" needle isn't long enough to get deep into the muscle tissue and that some of medication will be poorly absorbed because of this. Others say that there is no issue using a 1" needle if you're a reasonably thin...
  12. H

    Mixed Pregnyl (HCG)

    Thanks Nelson. Lesson learned here, I'll definitely be asking for powdered hCG for my next refill. My my protocol calls for 500iu of hCG on day 5 and 6 after my T injection but I will speak to my doctor about possibly increasing the dose during the first week. I also may ask about splitting...
  13. H

    Mixed Pregnyl (HCG)

    I'll talk to the pharmacy about sending me powdered hCG in the future. Should I assume that my current medication is no good now?
  14. H

    Mixed Pregnyl (HCG)

    I just received my package of medication to find that the hCG has already been mixed. Not a big deal, just wasn't expecting that. Perhaps I'm worrying a bit too much, but should I be concerned that the premixed medication probably sat in a hot warehouse or in the back of a truck for 4 days...
  15. H

    Injection Protocol

    100mg of test cyp every week 500iu of hCG twice per week My doctor wants me to start with weekly injections, but said that I can split the dose and inject twice per week if the need arises.
  16. H

    Mixed Pregnyl (HCG)

    Great, thanks for the reply.
  17. H

    Mixed Pregnyl (HCG)

    Does the powdered hCG need to be kept cold prior to reconstitution? Or is it only a concern once it's been mixed with the bac water? If the powder needs to be kept cold, how do compounding pharmacies achieve this during shipping? I'm guessing some type of cold pack might be used, but that...
  18. H

    Mixed Pregnyl (HCG)

    That's exactly what I was looking for. Thank you!
  19. H

    Mixed Pregnyl (HCG)

    Thanks! I edited my post above to include a couple of questions. I'd love to hear your opinion if you've got one. I'll probably wait to post my bloodwork until my 2 month follow up labs. I'm past the point of trying to figure out why my testosterone levels are low. I've had 4 or 5 sets of...
  20. H

    Mixed Pregnyl (HCG)

    I found this post via Google search and made an account just to thank you for putting all of this together. This post answers just about every question I had about hCG. I will be starting TRT soon and will certainly be using this website as a resource. Thanks again! Edit: One question I...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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