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  1. W

    Major Reduction of T after Cream

    Doc said once in AM.
  2. W

    Major Reduction of T after Cream

    Actually, I feel good, but am concerned about numbers, meaning T levels 35%-45% lower than pre-treatment and DHT is 2.5X higher, while Estradiol and SHBG are very similar. The conversion to DHT is irreversible. Do DHT levels vary throughout the day like T, which people here are saying I captured...
  3. W

    Successful Story with Testosterone Cream Protocol

    DHT went from 36 to 95 over same period. Does cream have trough issue if it had been nearly 24 hours since prior application when measuring T (but trough doesn’t apply to DHT levels, or estradiol or SHBG, only T)?
  4. W

    Major Reduction of T after Cream

    Update on Labs: DHT before T cream: 36 DHT after, lab at same time T measured: 95 So if the issue is trough was measured for Testosterone, is it not same for DHT?1 Or, am I over converting T too much to DHT, which is irreversible?
  5. W

    Major Reduction of T after Cream

    Excellent question, and I had thought about trough but didn’t think it was parcel to cream application….it had been close to 22 hrs since prior AM application (meaning I applied the prior AM, then had an AM draw the next morning). TY.
  6. W

    Major Reduction of T after Cream

    Just started TRT, 200mg cream in AM to scrotum 6 weeks ago with 50mg DHEA and 100mg Pregnenolone. At start my labs were, and frankly felt very “good” generally, mild libido issues, wanting to merely optimize overall health and vitality (active 55 YO), all other labs normal/optimal incl Thyroid...
  7. W

    Successful Story with Testosterone Cream Protocol

    Been on 200mg cream for 6 weeks, 50mg DHEA and 100mg Preg. T has gone from 502 to 187, and Free has dropped commensurately. Estradiol and SHBG stayed same, while my LH has hit the floor. DHT was low normal before and while I’m waiting for that lab to come back I’ll assume it’s high, although I...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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