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Defy Medical TRT clinic doctor
  1. F

    An Unusual Source of Anxiety

    Now that I pay attention to this phenomenon, Natesto is one of the culprits. I think (but am not sure) that it's less severe with Natesto. Maybe the overall levels aren't very high and thus the drop is less severe? In the past, I have been on Natesto continuously for up to six months at a...
  2. F

    Trans scrotal testosterone cream application is a game changer

    I hear you. That said, there are tons of threads about sleep. I have had some insomnia issues that, at the time, I felt confident were related to TRT. That said, I am generally under treated these days, so sleep is decent.
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    Trans scrotal testosterone cream application is a game changer

    Also, I’m curious, how are you decided to do the evening dose? Were you doing that from the outset because you thought you should, or were you doing it because you were crashing and/or feeling bottomed out in the afternoon and use that to alleviate those symptoms?
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    Trans scrotal testosterone cream application is a game changer

    Yes, I think these are great points. I have actually in the recent past wondered if I made the same assumption that you mentioned. I think being supraphysiologic and being under treated can both feel bad, and it can be hard sometimes to decipher what’s going on without labs. In another post, I...
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    Trans scrotal testosterone cream application is a game changer

    What time is your PM click? Any trouble with sleep?
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    Trans scrotal testosterone cream application is a game changer

    Oddly, that is very funny to hear. I am very similar. PTSD from all the bad experiences. One would think that just quitting altogether would be the answer, but that might feel even worse. Glad you are doing well. I might give it some thought.
  7. F

    Trans scrotal testosterone cream application is a game changer

    Is this 20% strength? I assume you’re putting all three clicks on in the morning currently and on the body, not the scrotum? Thanks.
  8. F

    Trans scrotal testosterone cream application is a game changer

    I echo @Gman86. As a fellow struggler, I am also genuinely happy for you. I get what you are saying when it comes to injections. I, too feel like something is just “wrong“ when I inject. I feel less so with Xyosted, but still not perfect. I have tried and tried to make creams work, with fleeting...
  9. F

    Nandrolone Experiences

    Curious to see if Anavar hits your lipids.
  10. F

    TRIGGER FINGER is OUT OF HAND (no pun intended)

    Sorry - I can't answer for Nelson. I'd recommend a standard, open release, which means stitches. The incisions are tiny and it's the safest way to avoid neurovascular structures. High success rate and fairly quick recovery.
  11. F

    An Unusual Source of Anxiety

    I started this thread a while ago and feel obligated to update it. As you'll see above, I pegged CoQ10 as the culprit in bouts of anxiety I was having a year ago. I have since determined CoQ10 was not the villain. I now take CoQ10 without any obvious anxiety patterns. On the other hand, I have...
  12. F

    I've been very depressed. I don't know what to do.

    From what I can see from your labs, TRT looks appropriate. Glad you are feeling better!
  13. F

    TRIGGER FINGER is OUT OF HAND (no pun intended)

    On occasion, an injection can totally resolve your symptoms. If not, trigger finger release is a quick recovery and will solve the problem.
  14. F

    I've been very depressed. I don't know what to do.

    Ah - good call.
  15. F

    I've been very depressed. I don't know what to do.

    @Nelson Vergel, is Sustanon available in the US? I have been curious about it.
  16. F

    Oxandrolone Treatment

    I’ve tried lots of different things. Don’t wanna bore you with the details. Willing to give Sustanon a try, but also worry a little bit about some of the longer acting esters. In any case, I don’t think you can get it in the United States, legally, can you?
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    I've been very depressed. I don't know what to do.

    Listen, brother, this forum is full of dudes whose testes are as good as not having any! You are not alone and you are not an imposter any more than a diabetic who requires insulin is an imposter. TRT is a piece of your picture, but I think you should simultaneously consider counseling. As you...
  18. F

    Oxandrolone Treatment

    Most veterans around here have heard me profess that I struggle with TRT. Very narrow therapeutic window. I recently asked Defy if there was something I could add to low dose TRT (ie, Natesto) other than testosterone that may help address some of my symptoms. I did not like nandrolone. They...
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    PATIENT SATISFACTION WITH ORAL TESTOSTERONE UNDECANOATE IN TESTOSTERONE-DEFICIENT MEN WITH PREVIOUS TESTOSTERONE THERAPY

    In fairness, I can’t say definitively if it was the Jatenzo, but I did strongly suspect it.
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    PATIENT SATISFACTION WITH ORAL TESTOSTERONE UNDECANOATE IN TESTOSTERONE-DEFICIENT MEN WITH PREVIOUS TESTOSTERONE THERAPY

    I have tried Jatenzo a few times. My input may be somewhat meaningless, but I thought I'd provide it. I have had a few trials that have lasted about a week or so. It seemed like early in the week, I'd really feel hypogonadal for several hours in the morning until the AM dose started to push t...
  21. F

    Natesto + Clomid

    @BigBeard411, I don't want to hijack your thread, but it's a good opportunity to compare notes. The last time I checked T levels on Natesto, I drew labs 45 minutes after my AM dose. Total T was 497 (not terrible) and free T was 67.5 (46-224). BUT, I was also only two weeks out of using a 50mg...
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    Terrible anxiety and constantly at a heightened state on 100mg a week

    12.5 mg per day may be a lot. I’ve read about people getting their levels above 1000 on 10 mg a day. Also, if you are on 12.5 mg per day, but started that immediately after being supraphysiologic already, it may take time for you to find a new balance.
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    Terrible anxiety and constantly at a heightened state on 100mg a week

    Excellent post.
  24. F

    Might quit 7 weeks in? Need help.

    Few ways to do it. You can do as you said, and stop for a few days and restart. Or, drop your dose to 8 to 10 mg a day and just ride it out. That way you’ll have some background replacement while the other stuff is metabolized and excreted out of your system. Over time, hopefully you’ll end up...
  25. F

    Might quit 7 weeks in? Need help.

    12.5 mg per day may still be a lot. You also may have to allow your system to “wash out“ some of your existing testosterone before a daily dose will be tolerable.
  26. F

    Might quit 7 weeks in? Need help.

    Sorry to hear about your struggle, brother. I think what you are going through is actually fairly common on TRT. I have personally experienced a little bit of what you described in bits and pieces. I think the advice to go on a low-dose, daily injection is sound. When you’re doing more frequent...
  27. F

    Testosterone mixed with MCT oil

    Gents, can anyone chime in on a good pharmacy that will provide legitimately compounded testosterone in MCT with an Rx? Strive only ships to a few states and South Lake does not appear to be answering phone calls or emails...
  28. F

    Feverfew Experience

    Great advice. Where do you get your ginger? Is there a brand you like?
  29. F

    Natesto + Clomid

    Sorry, forgot to answer your other question. I was on Pregnyl, which I got from a local, small pharmacy. No problems filling it with a prescription from my local doctor. It is kind of expensive. I want to say around $120-150 for a 10cc vial. That said, you can use that vial until it is no longer...
  30. F

    Feverfew Experience

    I have some riboflavin on hand. Have tried it here and there. Probably need to stick to it. I have never tried ginger powder. Do you have experience with it? Seems like a reasonable thing to try.
  31. F

    Natesto + Clomid

    I actually did not go off of hCG for anxiety. I went off of it because I got tired of the daily injections, and now that I try to go back on it, it produces anxiety. When I was taking it out on 100 IU per day.
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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