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Defy Medical TRT clinic doctor
  1. G

    Vitamin D May Slow Cellular Aging

    IMO, Vitamin D plus k2 is worthwhile just for the benefits to the innate immune system alone. Everything else is a nice bonus. Above 50 is apparently the sweet spot. Pneumonia is a fairly big risk for may of us.
  2. G

    HCT and blood donation

    Bloodletting tends to correlate with longer life and there are some fairly exotic theories as to why. One of the simpler benefits is that it reduces the chances of Iron overload which is something you certainly don't want.
  3. G

    Can blood work be incorrect?? Really confused

    Regarding the breathing issues, something you may want to look into is nebulizing hydrogen peroxide. You need to dilute it with saline, but I saw it have incredible affects during Coivd, restoring people's breathing to normal within a matter of minutes. Do your own due diligence but it seems...
  4. G

    Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

    The boswellia definitely seems to help me with my hip, leg and knees. I had not heard of black seed oil for inflammation but have some so I'll give it a try. For joint pain, the Gunthers methol rub and diclofenac gel both seem to help a lot, as well as BPC 157.
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    Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

    The Vitamin E gurus emphasize that a full-spectrum Vitamin E should be used that includes all Tocopherols and tocotrienols. Chris Masterjohn recommends the Tocosorb brand. Also, I have noticed benefit from Boswellia, something that gets very little publicity. Curcumin can help too and has...
  6. G

    Can blood work be incorrect?? Really confused

    It sounds to me like the root of your issues is not hormonal, but hopefully Defy can still help with that. There is a lot of info in TRTGUY9's thread about chronic fatigue and brain fog. Ideally you can find a good holistic/integrative doc but there are not too many out there. You may want to...
  7. G

    Can blood work be incorrect?? Really confused

    Is there a dosage/protocol where you consistently feel/perform well? My two cents is that when all else fails, get into a state where you look/feel/perform well and if numbers like HC aren't optimal, manage it as best you can but give them a year or so of monitoring and see how they vary over...
  8. G

    7.5mgs daily labs

    Also, depending on what dimension you need/want further improvement on, there may be approaches other than more T to achieve what you need.
  9. G

    New to TRT. Received first labs. Concerned and need help.

    Yes, donating blood will briefly lower HCT, however there are other benefits, the primary one being prevention of iron overload. The is some mechanism by which long runs apparently lower iron, however other than that, bleeding of some form and chelation, there is no way to get rid of iron, and...
  10. G

    Can blood work be incorrect?? Really confused

    As someone who's had some unexplained variation in test numbers myself, there's something to be said for staying on a protocol for while that in theory should work, and then seeing how your numbers align over a few measurements. My HCT was elevated and then dropped right back down after a while...
  11. G

    New to TRT. Received first labs. Concerned and need help.

    Three more random thoughts that occurred to me... - You might want to have one of the hair analysis tests done that measure mineral status. They're fairly cheap and might give you hint at an issue - If you have access to a sauna at your gym it is worth trying since sweating is one of the body's...
  12. G

    Hello from NC

    Something else you might try is just to stop altogether for about 10-15 days. If things dramatically improve at some point during that time, that would be a clue that your sweet spot is somewhere lower and you can restart at a lower dose. In my early days of TRT I used to come off for a couple...
  13. G

    Updated Labs - Help Please

    IMO, if you are in a generally good place, I would stay where you are for a while and see if your e2 improves over time. It's hard enough to get symptoms sorted out, let alone trying to optimize numbers as well. It's impossible for me to tell if the brief supplemental e2 possibly reset my...
  14. G

    Updated Labs - Help Please

    I've had issues with unexplainably low E2 as well but it seemed to resolve after a while and rose to more normal levels (a while being a year or so). A lot of things I wouldn't have expected can interfere with the aromatase enzyme, such as zinc, so you might want to review you supplements and...
  15. G

    New to TRT. Received first labs. Concerned and need help.

    How about starting a thread dedicated to whatever it is you're arguing about and leave this and other threads to the specifics of the OP's topic. This has become like bar fight that spills out of one bar and goes up and down the street into other bars. My contribution to that thread would be...
  16. G

    New to TRT. Received first labs. Concerned and need help.

    It's way more nuanced. Some compounds, specifically Anadrol, are well-known to make people look red. There are plenty of people who likely have high-blood pressure. The "dry" look of thin subQ fat layer can make some people look red. Boldenone can raise HCT. and increase vascularity. But the...
  17. G

    Can blood work be incorrect?? Really confused

    There are other options. What issues are you looking for the TRT to resolve?
  18. G

    Can blood work be incorrect?? Really confused

    For results that extreme, my approach is to immediately test again if possible and assuming no symptoms. I had elevated HCT for a while and I can say that it is essential that you be fully hydrated to get an accurate test. I would schedule your tests late morning and drink at least half a gallon...
  19. G

    Advice and next steps. 38 years old with 305 total t

    First, IMO, there are many things you need to explore before going on external T. It is nowhere near as simple as many make it out to be. Since your sexual function is still fairly good, I would be doubly cautious because, as many men have reported, TRT can mess that up and not have it resolve...
  20. G

    New to TRT. Received first labs. Concerned and need help.

    Sparky's comments remind me that intestinal permeability (leaky gut) could be at play here too. There are tests for that (LPS?) but it seems better to just follow a protocol that would cure/prevent the leaky gut, such as Dr. Gundry's Gut Check protocol.
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    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    In general, poor health is accompanied by a decline in Nitric Oxide production. The Viagra class of drugs blocks an enzyme that breaks down nitric oxide so it indirectly increases Nitric Oxide if someone is producing good amounts in the first place. Dr. Kendrick points out that these drugs far...
  22. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    I do too many things to list but I made a very quick starter list below. While the book has as section on specific recommendations which, for example, caused me to start niacin again and measure LP(a) and homocysteine, the bigger impact for me was that by better understanding mechanisms of harm...
  23. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    Taking magnesium, K2 and vitamins A, K and E (full spectrum) may help absorption, but that sounds strange. Some infections "hijack" vitamin D, but I really just don't know. You might look into Chris Masterjohn's writing on the topic particularly around interaction with the parathyroid hormone.
  24. G

    New to TRT. Received first labs. Concerned and need help.

    Some comments in no particular order. - Your Vitamin D reminds me that there are apparently some infections that use the Vitamin D receptor as an entryway into cells, and for those infections Vitamin D can make actually make things worse. Dr. Michael Ruscio (who you should also look into) did a...
  25. G

    New to TRT. Received first labs. Concerned and need help.

    I agree with everything Funk said. Regarding mold, which I forgot to mention. I think what you want is a test that determines if you have been exposed and have some sort of damage from it. You could have been exposed elsewhere. A doc who specializes in that type of thing would be good to...
  26. G

    DHT Cream Plus Testosterone Propionate = Major Libido Boost

    I really admire the creativity here, but I'm puzzled by using crushed tadalafil. Since you're basically (potentially, dependent on absorption) injecting the fillerr and binders, I would think there could be a risk there if those are things that are not absorbed in the digestive tract when taken...
  27. G

    New to TRT. Received first labs. Concerned and need help.

    Your symptoms scream chronic fatigue syndrome and hopefully someone here with experience on that topic will chime in (possibly @FunkOdyssey ?) which if IIRC can be from chronic infections and/or micronutrient deficiencies. From what I've heard, mainstream doctors are fairly awful at resolving...
  28. G

    Experiences and Questions: Personal Experiments with Oral Native Testosterone Base & Enclomiphene (TRT+), Testosterone Propionate, HCG and more

    This is another reason I am not a fan of ChatGPT. First, the point of the book is to propose a model of heart disease which actually fits the data we have about CVD. While there are a number of recommendations in the book. the bigger picture is that there are literally hundreds of risk...
  29. G

    Factors Involved in Immune Resilience and Longevity

    It's puzzling that, at least based on the notes, he doesn't say anything about strengthening the innate immune system, specifically with Vitamins and minerals like D, C, and Zinc. Supplements like Beta Glucans apparently help as well.
  30. G

    Alcohol Consumption and TRT/HCG

    DHM (dihydromyricetin) is an amazing compound and among other things aids in metabolizing alcohol.
  31. G

    Alcohol Consumption and TRT/HCG

    While I would never recommend drinking in large amounts, or in any amount for someone who does not have a good relationship with alcohol, there are three big problems with the anti-alcohol push. First, the observational studies have grouped heavy drinkers in with light social drinkers. I have...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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