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Defy Medical TRT clinic doctor
  1. W

    TRT Dose question

    I remember envying your success on 1x weekly 60mg. Loved the simplicity of it. Since you seem to do well on it other than first 1-2 days, I would agree with some of the other posters to a modest dose reduction with moving to 2x weekly to blunt that peak.
  2. W

    Still trying to figure this out - 120mg to 100mg to now 80mg - what a rough week

    If it were me, I would ditch DHEA until you dial in your dose. Many TRTers including yours truly feel shitty on DHEA supplements.
  3. W

    I’ve gave in and started a cycle after lots of TRT frustration. Can I PCT off altogether or back on TRT

    You've already identified a potential culprit other than TRT that could be contributing to your issues. Overtraining can hit you hard - shitty sleep, general malaise, wired but exhausted feeling, etc. I have been guilty of this many times. As you get older, its very easy to overdo it...
  4. W

    First set of Follow Up Labs since Starting TRT. Looking for Feedback

    Case in point - my last blood panel on 7.5 mg daily = TT 755 / FT Verm 15.6. There is a 100+ thread on another forum about guys on TC/TE 10mg daily (70mg per week). The majority of them are top end of physiologic range or over. And these are bodybuilder types...
  5. W

    Building a TRT protocol around hCG

    Are we talking about Pregnyl pharma brand name HCG or compounded HCG? From the threads I've read here, it sounds like most are having more success with Pregnyl
  6. W

    Any Testosterone Propionate Compounding Pharmacies left?

    Yes even 3.5 days too much fluctuation for me. But if you feel relatively smooth on 3.5, then low dose daily TNE or TS might be a nice kicker in the morning. Let us know if you try it out
  7. W

    starting injections soon a little nervous

    For intramuscular injections into delts, you want 1/2 or 5/8 as @FunkOdyssey mentioned. I use 30 gauge 1/2" ones while other use 27 or 29 gauge. For subq in belly fat area, you want to use 31 gauge 5/16 needles. You can't even feel it. I recommend these ones...
  8. W

    Does anyone else have zero libido without HCG?

    Can you provide details on your TRT and HCG doses and frequency? How long before libido showed up on HCG?
  9. W

    Any Testosterone Propionate Compounding Pharmacies left?

    I recall several posts of guys feeling better on 1x weekly injections. I have tried every injection frequency under the sun, and always revert to daily injections. I found 1x weekly or even 2x weekly too much of a boom-bust cycle. Just shows yet again that doses, frequencies and esters are...
  10. W

    Kyzatrex - sudden emptiness feeling in head

    How about using Kyzatrex 1x daily to create a morning spike while maintaining a base with daily injections of TC or TE? I am experimenting with something similar using TE + TNE for the morning spike.
  11. W

    Any Testosterone Propionate Compounding Pharmacies left?

    In theory yes and it sure felt that way for me. I am currently experimenting with using daily Enanthate injection as a steady-state base followed by separate TNE injection to create a morning spike - similar to the TE/TP blend that our own @Cataceous pioneered. So far the TE/TNE feels very...
  12. W

    Any Testosterone Propionate Compounding Pharmacies left?

    There is much debate about that, but based on my experience TS is faster hitting than TNE. In fact, I am subjectively feeling even small doses of TNE 2mg peaking at 2-3 hours with effects well into 6-7 hours post-injection. Not ideal for maintaining HPTA, but good for creating daily spike.
  13. W

    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    Fascinating! I wondered whether this possible. You are truly a mad scientist. On a related point, why don't pharma companies use smaller crystals for Suspension? If they could, would it help dissolve the testosterone in water? Or is that why there is TNE oil-base as alternative? I would...
  14. W

    Any Testosterone Propionate Compounding Pharmacies left?

    I have tried 2x day prop. Was better than 1x day prop, but not huge difference. If you are willing to inject 2x per day with fast acting T, I have been experimenting with TNE 2x day. Much more noticeable spike (in a good way) than prop and deeper trough at night. The tricky part is that TNE...
  15. W

    Building a TRT protocol around hCG

    When you experience this libido from HCG, it is steady? Or a spike x hours after injection? Also, are the results sustainable when taking EOD HCG for 6+ consecutive months? Or will you have to cycle on and off? The reason I ask is because protocol change has been the only thing that ever...
  16. W

    Pharmacokinetic Profile of Testosterone Suspension: A Case Study

    Thanks Cat for the attempt to isolate the effects of Suspension. What are your next steps? Would be interesting to see the TT/FT/HPTA blood results when available I continue to dabble with TNE oil-base which subjectively speaking seems to stick around longer than water-based Suspension
  17. W

    Kyzatrex - sudden emptiness feeling in head

    What was your dose and blood test on Kyzatrex?
  18. W

    Anxiety from Kyzatrex?

    Any updates?
  19. W

    Still trying to figure this out - 120mg to 100mg to now 80mg - what a rough week

    Don't worry you are doing everything right. You just need to ride out this rough patch. I have had same experience over the years with major headaches and joint aches when dropping 20% dose (or going cold turkey). Its a big change for the body to adapt to. Find a dose where you have a good...
  20. W

    Advice on next steps - mid-low free T

    Running is notorious for over-training depending on how hard you are pushing it. If you really wanted to rule it out, you could take it easy for 1-2 weeks then test again. Of course, if you have the itch to try TRT, nobody is going to stop you. I would just forewarn that TRT is not a...
  21. W

    Advice on next steps - mid-low free T

    How was FT measured? Did your run it through calculator below? https://www.issam.ch/freetesto.htm 30 years old is so young for TRT. It's a lifetime commitment. While there is no harm in trying it, you can piss away a lot of time, energy and money trying to dial in your protocol (don't ask...
  22. W

    Starting TRT Soon

    Don't fall for TRT myth that 100mg weekly is a low dose. It took me several years to learn that guys respond differently to dose levels. Some handle 200mg no problem, while other such as myself are in 50-60mg range. If you feel over-medicated, you probably are. In my experience, shitty...
  23. W

    Advice on next steps - mid-low free T

    Funk - does this mean you have switched your protocol from propionate to oral?
  24. W

    Advice on next steps - mid-low free T

    Doc - my educated guess it that exogenous T is not the answer to your problems especially considering many of us would kill your natural blood test numbers. Your symptoms are more in line with overtraining.
  25. W

    Testosterone dropped after a few months on the same dose

    Do you feel any different now versus period of first test (not including the initial honeymoon period)?
  26. W

    Xyosted Prefilled Autoinjector for Subcutaneous Testosterone Administration

    I actually tried it at one point because I had read Xyosted contained no preservatives. I had given myself hundreds of subq inejctions before Xyosted and damned if I couldn't get that auto-injector to work. I just don't have enough belly fat. It was comical. I later thought about filling...
  27. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Apologies for getting off thread topic, but can you provide more details on wife's protocol? Sounds like 2-2.5 mg E3.5 days shallow IM, correct? What ester is she using?
  28. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    So I take it your sleep eventually normalized at the higher doses?
  29. W

    Madmans pick BD 28G LDS insulin syringe/permanently attached Micro-Fine™ IV Lo-Dose™ thin-wall needle - Delivers 27G Flow Rate

    And don't forget BD's 31 gauge ! https://www.excelmale.com/threads/daily-subqers-5-stars-for-bd-ultra-fine-insulin-syringe-31g-3-10cc-5-16.24643/
  30. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    Interesting. Admittedly, I have not tried to power through that feeling because the heart palpitations freak me out. But its something for me to keep in mind. Have you found the side effects eventually dissipate with such a large dose? I recall you quitting TRT early on because you felt...
  31. W

    Why do some men need supraphysiological doses of testosterone to achieve normal levels

    What fascinates me is how some guys are able to tolerate large daily doses and still function normally at supraphysiologic levels. For example, a mere 10mg of daily prop felt like speed to me. Difficult to concentrate; too wired to sleep; heart palpitations, etc. And yet some guys can take...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic doctor
Defy Medical TRT clinic

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