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    Which E2 test is more reliable (Sensitive or Roche)?

    Thanks Gene. I'm very lean - an urologist I saw a while ago for a different issue told me that I was very unlikely to have to worry about my estradiol as long as I stayed lean. Is this generally true? If so - it sure is a motivation to stay the course as far as exercise and diet.
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    Which E2 test is more reliable (Sensitive or Roche)?

    Thanks Nelson. I purchased your book a while back and keep it handy at all times, and while it does state that the range should be 20-30 pg/mL I did not see any clarification as to which test was appropriate for that range. Maybe the next edition??
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    Which E2 test is more reliable (Sensitive or Roche)?

    My last test showed my total T at 758. The E2 sensitive assay was 19 pg/mL (3-79 reference range), while the Roche ECLIA was 41.9 pg mL (7.6 - 42.6) reference range. Compared to a test performed 2 months ago, the sensitive was 14, while the Roche was 23.2 where the total T was 560. I...
  4. C

    Arimidex and how I should take it

    I wondered - over the long-term - is it inevitable that all men will eventually need to take anastrozole? What if you are extremely lean and maintain that low amount of body fat?
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    Test Results Analysis

    Thanks Keith - definitely will show my endo. He does seem open-minded to tests that I suggest.
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    Test Results Analysis

    They did not perform any labs prior to starting TRT - they basically said - "Whoa dude - your overall is only 137" and started Androgel right away. I had no idea that my issues could be to low T - and I was such a trainwreck at that time - I just went along with their recommendations - I was...
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    Test Results Analysis

    A kind of query here - would going to injections be possibly a recommended alternative? I know everyone is different - but my understanding is that injections do not drive DHT up as much as gels do.
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    Test Results Analysis

    Thanks for the replies. First - the endo did perform tests and could not find any markers pointing to secondary, so he implied it was primary. As for applying the gel - I apply on my shoulders, down the back a little, to my upper arms. I'm also a very lean guy, with a BMI of 21 - if...
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    Test Results Analysis

    Hi - These results are after starting 4 pumps of Androgel in July 2013. My initial overall T was 137. While I feel much better now than I did before - I still have my doubts as to using Androgel over the long-term. I have an upcoming physical with a new PCP - and I plan to take Dr...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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